Gene Information

Name : lysS (jk1200)
Accession : YP_250982.1
Strain : Corynebacterium jeikeium K411
Genome accession: NC_007164
Putative virulence/resistance : Unknown
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 1407855 - 1411103 bp
Length : 3249 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
GTGAAAGCTGAACCCAGAAGCACTCCAGGCCCGCTAGCAGGATCACGTGGATTCTTTCCTCGCTTCATCGGAACCATCCT
CTGCGCCTATGCGCTAATGGCGCTAGTGCTGAGTATCTCCACCGCAGCGCGCGTGCATGTTCGCCAGTTGCTGGTGGTGA
TGGATAATGTCTTCCTGCCCGTCCCCGTGCCCTCCGTCGCGTGGTCCGCCGCGCTGTTGGTGCTGGGCATAGGTCTCTAC
CAGGCCAAACGTGCCGCCTGGGTGGTAGCCGTGGCCGCGCTGCTGATCCTTAACTGCAGCAACCTGCTACTGCTTTTGCT
ACCTCAATACTTCGACGTTGGCCCTGAGTGGGCGCACTCGCTTTTCATAGCGGGAATGGTCGTACAGTTCTTTTTGCTGC
TCCTGATGATCTGGCGACGTAGAGACTTCTACACGCACACAGTCAAAGGCGCGATCCTGGCTGCCTTCCTGCTCTGGCTG
GGCGGCAGTGTTGCCGTGTTCCTGATTGCTTTGGTGCTGGTGCATTTCTTCCATGGCAACCTGGCGCCGGAATGGCGGGC
GCTGTGGGCGCTGAACCACTCTGCTGGATTCTCCCTCTTCAACCACGTACATACGGGCGGCCACCCGCCGAAGCTTATCT
CCTTCCTGGTCTCCGCCCTGTCTGCGATGGTGTTGCTGGCAGCCGGATTGATGTTGCTGCGCTCCCATCGGGACCAATTC
GGCATCACAGCTGAGGACGAATCTGCTCTGCGAGCCCTCATCCGACGTTTCAACAGCAATGACTCGCTGGCCTACTTTGC
CACCCGGCGGGATAAGTCCGTGGTCTACGAACCTAAGGGCCGCGCGGCAGTGACCTACCGAATTGAGGCCGGTGTGTGTT
TGGCGTCCGCCGACCCCATTGGCGATCCACGGTTCTGGGATCAGGCAGTCGCGGCTTGGCTGGACCGAGCACGAGCCTTT
GGGTGGGTGCCGGCGGTCATGGGGGCGTCCGAACAGGGAACAAGAGCCTACGAGAAGCAGGGGCTAAGCTCCATCCACTT
GGGCGACGAAGCTGTGATCGATACGCAGAACTTCCACCTTTCCGAGTTACGGGAAGTGCGTCAGGCGCGCGCCCATGCGC
AAAAGGCCGGCGTGCGGGTGCGTATCCGGCGCCACGGCGAACTCAATGCCCAAGAGATGCAGCGCGTAGACGACCTGGCT
GAAAAGTGGCGGGATACAACCGACGAACGTGGCTTCTCCATGGCGCTCGGAAGGCTCGGCGATCCACAAGACAAGGACTG
TCTCTTGGCAGAGGCCCTGGTGGGGGACGAGACAGTAGCAGTGCTGTCGTTTATCCCCTGGGGCCTAAATGGCGCCTCGT
TGGACCTTATGCGTCGCAGCCCGGAAGCGCCCAACGGCACGGTCGAAGCGATGATCGTGGCCCTGTGCACCGAAGCGAAC
CTGCACAAGCTCTCTCTGAACTTCGCAGTTTTCCGCGAACTGTTCGCCAGCGAGGATGCCGTGGCCGTGGGGCCTATTCG
CAGGCAAGCGCGCCGGGTGCTGACATATCTGTCGAAGTGGTGGCAGATGGAGACGCTCTATCGCTCCAACCAGAAGTACA
AGCCAGTGTGGATCCCGCGGTATGTCTGTTACCCGGATTCCTTGTCGATGGCGCGCGTGGGCATTGCATCTGGCATTGCG
GAGGGCTTCGTACCCACTTTCGGCAGCGCGTTCGGTAGTTTGTTTGGGCGGGGAACCGAGGAGCATCGTGAATACGCCAC
CAGCGGGCAGCCCGAAGCAGCACAGGCGCTGAACTACGTTGAACAGCTAACGGATGCCCACAAGAAAACCGCCAGCGAGC
AGACCGCCGTGCGAATCAAAAAGGCACTGGCATTGCGCGAAGCTGGGGTGGAGCCGTGGCCGGTCGCGGCGCGTGGTGCC
GGAGAACGCTCGGACGTTGCTGTGGTGCAGTGTGTTGAGATTGCCGAAGGTAGTGACGCCACCACTTCCGGCCCGCTGCG
CGTTTCAGGTCGCATCGTGGCCAAGCGCGAGTTCGGGGCAGTGTCCTTTATCGACCTGCGGGATGCCTCCGGCAAATGCC
AAGTTCTGGTCGAAGCACCGAAGGAAGAACTTGCCTCGAGACTGCGTGCCCTGGATCTGGGCGACCTGATTGCAGTGGTA
GGAACGCGCGGGCATTCGCGGACTGGCGAGCCTTCTCTGCTGGCAGAGGCCATCGAATTGGAGGCGAAGGATCTGCACCC
CCTGACGCGCCGTGGCGCGGGGATCGGGGAGGTCAACGCCCGACTGCGTGCCAGGTCGGTGGTGAACGCCGCGATCCGCC
GCACGCTGGGAGACTTGGGATTCATGGAGGTGGAAACCCCGATTCTGCAGCGTGTTCACGGTGGTGCGAATGCGCGCCCA
TTTAAGACGCGGAGTAACGCTGCGAATCAGGACCTCTACCTGCGCATCGCCCCGGAGCTGTACCTGAAACGCCTGCTGAC
CCAAGGGGCCGAGAAGGTCTACGAGCTGGGACGAGTGTTCCGTAACGAGGGTGTGGACGCTACCCACAACCCGGAATTTA
CAACTGTGGAAGCCTACGAAGCGCACGGCGACTACGAGTCGATGCGCTGGGTAGCTCAGCGGATCATTCAGGCGGCCGCC
ACTGCTTACCACGGGGAGCCGCTGGTGCTGGACCCGGAAGGCAACCTGGTGAGCATCGCCGAGAACTTCCCGGTGAAGAC
CGTGTACGGGGCCATCAGTGAGAAGGTGGGGCAATCGATTACCCCGGAGACGAATTTCGAGACGCTGCTAGAGCTGTGTG
CTGTCCATGGGATAGCTACCCAGCCAGGGTGGGATTCCGGTGAGGTAGTGCAGGAAATGTACGAGGCTCTGGTCGAATGC
ACCACCACTATGCCGACGTTCTACACGGACTTTCCCACTAGTGTCTCGCCGCTGACCCGCCAGCACCGAAGCCAGCCGGG
CGTGGCCGAGCGCTGGGACCTCGTTGCCTGGGGAGTAGAGCTCGGAACAGCGTATTCGGAGCTTACCGACCCTCTGGAAC
AACGTGACCGCCTGGAGGCGCAGTCGCTGAAGGCAGCGGGTGGCGACCCGGAAGCGATGGAGGTTGATGAGGCGTTTCTG
CGTGCCTTGGAAGACGGCATGCCGCCGACTGGCGGGTTGGGGCTTGGCGTTGACCGCCTCATCATGCTGCTCACGGGGCG
TTCAATCCGGGAGGTCCTCAGTTTCCCAGCCCACCCCGGCGGGCAATAA

Protein sequence :
MKAEPRSTPGPLAGSRGFFPRFIGTILCAYALMALVLSISTAARVHVRQLLVVMDNVFLPVPVPSVAWSAALLVLGIGLY
QAKRAAWVVAVAALLILNCSNLLLLLLPQYFDVGPEWAHSLFIAGMVVQFFLLLLMIWRRRDFYTHTVKGAILAAFLLWL
GGSVAVFLIALVLVHFFHGNLAPEWRALWALNHSAGFSLFNHVHTGGHPPKLISFLVSALSAMVLLAAGLMLLRSHRDQF
GITAEDESALRALIRRFNSNDSLAYFATRRDKSVVYEPKGRAAVTYRIEAGVCLASADPIGDPRFWDQAVAAWLDRARAF
GWVPAVMGASEQGTRAYEKQGLSSIHLGDEAVIDTQNFHLSELREVRQARAHAQKAGVRVRIRRHGELNAQEMQRVDDLA
EKWRDTTDERGFSMALGRLGDPQDKDCLLAEALVGDETVAVLSFIPWGLNGASLDLMRRSPEAPNGTVEAMIVALCTEAN
LHKLSLNFAVFRELFASEDAVAVGPIRRQARRVLTYLSKWWQMETLYRSNQKYKPVWIPRYVCYPDSLSMARVGIASGIA
EGFVPTFGSAFGSLFGRGTEEHREYATSGQPEAAQALNYVEQLTDAHKKTASEQTAVRIKKALALREAGVEPWPVAARGA
GERSDVAVVQCVEIAEGSDATTSGPLRVSGRIVAKREFGAVSFIDLRDASGKCQVLVEAPKEELASRLRALDLGDLIAVV
GTRGHSRTGEPSLLAEAIELEAKDLHPLTRRGAGIGEVNARLRARSVVNAAIRRTLGDLGFMEVETPILQRVHGGANARP
FKTRSNAANQDLYLRIAPELYLKRLLTQGAEKVYELGRVFRNEGVDATHNPEFTTVEAYEAHGDYESMRWVAQRIIQAAA
TAYHGEPLVLDPEGNLVSIAENFPVKTVYGAISEKVGQSITPETNFETLLELCAVHGIATQPGWDSGEVVQEMYEALVEC
TTTMPTFYTDFPTSVSPLTRQHRSQPGVAERWDLVAWGVELGTAYSELTDPLEQRDRLEAQSLKAAGGDPEAMEVDEAFL
RALEDGMPPTGGLGLGVDRLIMLLTGRSIREVLSFPAHPGGQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lysS1 YP_005682181.1 lysyl-tRNA synthetase Not tested PiCp 7 Protein 2e-155 43
lysS1 YP_005684273.1 lysyl-tRNA synthetase Not tested PiCp 7 Protein 4e-156 43
lysX YP_003784331.1 lysyl-tRNA synthetase Not tested PiCp 7 Protein 4e-156 43
lysS1 YP_005686365.1 lysyl-tRNA synthetase Not tested PiCp 7 Protein 4e-156 43