Gene Information

Name : tkt (jk0992)
Accession : YP_250774.1
Strain : Corynebacterium jeikeium K411
Genome accession: NC_007164
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 1172229 - 1174319 bp
Length : 2091 bp
Strand : +
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
GTGACTCTCTCCCCAGAACAGCAGGCACTCACCGTGCGCAACTACCCAGCGGACTGGACGGAGACCGACACGCGCGCGGT
CGACCTTGCCCGTGTGCTGGCCGCAGACGCAGTGGAAAACTGCGGCTCGGGCCACCCCGGCACGGCGATGAGCCTGGCGC
CGCTGGCCTACACGCTGTACCAGCGCGTACTTCGCCACGATCCGCAGGACGTGCACTGGGTCGGTAGGGATCGCTTCGTA
TTGTCTGCGGGCCACTCGTCTCTGACCCAGTACATCCAGCTGTACCTGGGTGGCTTCGGCTTGGAGCTGGAGGATCTTCA
GGCCCTGCGCACCTGGGGGTCCAAGACCCCGGGCCACCCCGAGGTGCACCACACCGATGGCGTGGAGATCACCACCGGCC
CGCTGGGCCAGGGACTGGCATCCGCGGTGGGTATGGCGATGGCCTCCCGCCGCGAGCGCGCATTGTTCGACCCTGAGGCT
CCGGCCGGAGAGTCCCCATTCGACCACTTCATCTACGTCATCGCTTCCGACGGCGACGTCCAGGAGGGCGTGACTTCCGA
GGCTTCCTCCCTGGCGGGTACCCAACAGCTGGGTAACCTCATTGTCTTCTGGGACGATAACGGCATCTCCATCGAGGACC
AGACCGAGATTGCCTTTAACGAGGACGTCTCTGCTCGCTACGCCGCCTACGGCTGGCAGACCCTGGAGGTCACCGGTGAG
GATGTCGAGGGAATCCTGGACGCGGTCGAGCGCGCCAAGGCAGAGACCTCCCGCCCAACCTTCATTCGCCTCCGTAGCGT
CATTGCCTACCCAGCCCCGACGAAGATGGATACCGGTGCCTCCCACGGTGCGGCCCTCGGCGCGGAAGAGATCAAGGGCA
TTAAGCAGGCCCTGGACTTCCCCGATGAGCCGTTCCCGGTGGAGGACAACGTAATCACCCACACCCGCGGTCTGATCGAT
CGTGCCGCGGAGGCGCACAAGCAGTGGCAGGTTCTTTTTGACGCTTGGGCGGAGAACAACCCGGAGAACAAGGCTCTGTT
CGACCGTCTGTACTCCCGCGAACTTCCGGAGGGCTTCGACGCCGAGGTTCCCAGCTGGGAGGCCGGGGAGTCCCTGGCCA
CCCGCAAGGCTTCGGAGGCTACCCTGCAGGCTCTGGGGAAGACTTTGCCGGAGCTGTGGGGTGGTTCCGCTGACTTGGCT
GGCTCCACCAACACCATCATTAAGGGCTCCCCGAGTTTCGGCCCGGAGGCCATCAGCACTCGCAATTTCACTGCGGAGCC
GGGTGGCCGCAACCTGCACTTCGGTATCCGCGAGCACGGCATGGTCGCCATCCTGAACGGCATCGCCCTGCACGGCCCGA
CTCGCCCTTACGGTGCGACGTTCCTGCAGTTCTCCGACTACGCACGCGGCGCGGTGCGCCTGGGCGCCCTGATGAAGTCG
GATGTTTACCACGTGTGGACGCACGACTCCATTGGCCTGGGCGAGGACGGCCCCACCCACCAGCCAGTCGAGCACCTGGC
ATCCCTGCGTGCAATCCCCCACCTGGCGGTTATCCGCCCGGCGGACGCTAACGAGACCGCTGCGGGCTGGGTGGCTGCCC
TGCAGGCTGAGGAGTCCCCGAAGGCTCTGATCTTGACCCGCCAGAACGTCCCCGTGCTGGAGGGAACTCAACAGAAGGCT
GCAGAGGGCGTGGCCCGCGGCGCGTACGTGTTGGTCGAGGAGTCGACGGACACTCCGGAGGTCATCCTGCTGGCCACCGG
CTCCGAGGTGCAGCTGGCCGTGGAGGCCGCCAAGGAACTGGAGAGCCAGGGCGTGGGCACCCGCGTGGTCTCCATGCCGG
TCATGGAGTGGTTCCTTGAGCAGGATGCCGAGTACCAAGAGCAGGTTCTGCCGAGCAACGTGACGGCTCGCGTGTCCGTG
GAGGCCGGAATCGCCATGCCGTGGCACCGCTTTGTTGGCCTGAACGGCCGGACTATCTCTCTGGAGCACTACGGCGCTTC
GGCCGACTACCAGACGCTCTACCGCGAGTTCGGCATCACTTCCGAGGCAGTCGTCGCTGCCGCGCACGACTCCATCGCGG
CGAACAAGTAA

Protein sequence :
MTLSPEQQALTVRNYPADWTETDTRAVDLARVLAADAVENCGSGHPGTAMSLAPLAYTLYQRVLRHDPQDVHWVGRDRFV
LSAGHSSLTQYIQLYLGGFGLELEDLQALRTWGSKTPGHPEVHHTDGVEITTGPLGQGLASAVGMAMASRRERALFDPEA
PAGESPFDHFIYVIASDGDVQEGVTSEASSLAGTQQLGNLIVFWDDNGISIEDQTEIAFNEDVSARYAAYGWQTLEVTGE
DVEGILDAVERAKAETSRPTFIRLRSVIAYPAPTKMDTGASHGAALGAEEIKGIKQALDFPDEPFPVEDNVITHTRGLID
RAAEAHKQWQVLFDAWAENNPENKALFDRLYSRELPEGFDAEVPSWEAGESLATRKASEATLQALGKTLPELWGGSADLA
GSTNTIIKGSPSFGPEAISTRNFTAEPGGRNLHFGIREHGMVAILNGIALHGPTRPYGATFLQFSDYARGAVRLGALMKS
DVYHVWTHDSIGLGEDGPTHQPVEHLASLRAIPHLAVIRPADANETAAGWVAALQAEESPKALILTRQNVPVLEGTQQKA
AEGVARGAYVLVEESTDTPEVILLATGSEVQLAVEAAKELESQGVGTRVVSMPVMEWFLEQDAEYQEQVLPSNVTARVSV
EAGIAMPWHRFVGLNGRTISLEHYGASADYQTLYREFGITSEAVVAAAHDSIAANK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 2e-118 45
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 1e-119 44