Gene Information

Name : ureA (NTHI0667)
Accession : YP_248250.1
Strain : Haemophilus influenzae 86-028NP
Genome accession: NC_007146
Putative virulence/resistance : Virulence
Product : urease subunit gamma
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0831
EC number : 3.5.1.5
Position : 632419 - 632721 bp
Length : 303 bp
Strand : -
Note : Urea amidohydrolase gamma subunit; UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter

DNA sequence :
ATGCACTTAACTTCCAGAGAACAAGAAAAACTGATGCTTTTCCTCGCGGGCGAACTTGCGGCAAAACGCAAAGCACGCGG
CGTTAAATTAAATTATCCAGAAACCATTGCTTATATTGCGAGCCATTTACAAGAGGCTGCAAGAGACGGAATGAGTGTAG
CGGAAGTGATGCAATATGGCGCAACACTTTTAACTGTTGATGATGTCATGGAAGGTGTGGCAGAAATGGTTCATGAAGTC
CAGATTGAAGCTACTTTCCCCGATGGCACGAAACTTGTTACCGTGCATAATCCAATCAGATAA

Protein sequence :
MHLTSREQEKLMLFLAGELAAKRKARGVKLNYPETIAYIASHLQEAARDGMSVAEVMQYGATLLTVDDVMEGVAEMVHEV
QIEATFPDGTKLVTVHNPIR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureA YP_005686360.1 urease subunit gamma Not tested PiCp 7 Protein 2e-29 64
ureA YP_005682176.1 urease subunit gamma Not tested PiCp 7 Protein 2e-29 64
ureA YP_005684268.1 urease subunit gamma Not tested PiCp 7 Protein 2e-29 64
ureA YP_003784327.1 urease subunit gamma Not tested PiCp 7 Protein 2e-29 64
ureA NP_286678.1 urease subunit gamma Virulence TAI Protein 3e-21 59
ureA NP_287086.1 urease subunit gamma Not tested TAI Protein 3e-21 59