Gene Information

Name : hfeA (NTHI0481)
Accession : YP_248077.1
Strain : Haemophilus influenzae 86-028NP
Genome accession: NC_007146
Putative virulence/resistance : Virulence
Product : periplasmic chelated iron binding protein
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG0803
EC number : -
Position : 454749 - 455630 bp
Length : 882 bp
Strand : -
Note : Similar to: HI0362, Y362_HAEIN

DNA sequence : 
ATGCGAAATTCATTCAAAATTATGACCGCACTTGCACTTGGTTTATTTGCAATGCAAGCTAACGCAAAATTTAAAGTCGT
AACCACTTTTACCGTGATTCAAGATATTGCGCAAAATGTGGCAGGCAATGCAGCAACAGTGGAATCTATTACCAAACCAG
GTGCTGAAATTCACGAATATGAACCAACGCCAAAAGACATTGTAAAAGCACAATCTGCCGATTTAATTTTATGGAACGGC
TTAAATTTGGAACGTTGGTTTGAGCGTTTCTTCCAAAATGTTAAAGATAAACCTGCTGTGGTAGTAACAGAAGGTATTCA
ACCATTATCTATTTATGAAGGCCCGTATAAAGATGCGCCTAATCCACACGCTTGGATGTCGCCATCTAATGCTTTAATTT
ATATTGAAAATATTAAGAATGCGTTAGTGAAATACGATCCACAAAATGCAGCTGTGTATGAAAAAAATGCCGCTGACTAT
GCTCAAAAAATTAAACAACTTGATGAACCGCTTCGTGCAAAATTAGCACAAATTCCAGAAGCGCAACGCTGGCTTGTAAC
AAGTGAAGGTGCTTTCAGTTATTTGGCGAAAGATTACAACTTAAAAGAAGGTTATTTATGGCCAATCAATGCAGAACAAC
AAGGCACACCACAACAAGTGCGTAAAGTGATTGATTTAGTTCGTAAAAACAATATTCCAGTTGTGTTTAGTGAAAGTACA
ATTTCAGCGAAACCTGCACAACAAGTAGCTAAAGAAAGTGGTGCAAAATACGGTGGCGTATTGTACGTTGATTCACTTTC
TGCGAAAAACGGCCCTGTGCCAACTTATATTGATTTGCTTAACGTCACTGTATCAACCATTGTTAAAGGATTCGGAAAAT
AA

Protein sequence : 
MRNSFKIMTALALGLFAMQANAKFKVVTTFTVIQDIAQNVAGNAATVESITKPGAEIHEYEPTPKDIVKAQSADLILWNG
LNLERWFERFFQNVKDKPAVVVTEGIQPLSIYEGPYKDAPNPHAWMSPSNALIYIENIKNALVKYDPQNAAVYEKNAADY
AQKIKQLDEPLRAKLAQIPEAQRWLVTSEGAFSYLAKDYNLKEGYLWPINAEQQGTPQQVRKVIDLVRKNNIPVVFSEST
ISAKPAQQVAKESGAKYGGVLYVDSLSAKNGPVPTYIDLLNVTVSTIVKGFGK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
sitA NP_806464.1 iron transporter periplasmic-binding protein Virulence SPI-1 Protein 2e-94 68
sitA NP_461782.1 periplasmic binding protein Virulence SPI-1 Protein 2e-94 68
sitA AAD41065.1 SitA Virulence centisome 63 pathogenicity island Protein 2e-94 68
sitA YP_217781.1 iron transporter: fur regulated Virulence SPI-1 Protein 2e-94 68
sitA NP_457255.1 Iron transport protein, periplasmic-binding protein Virulence SPI-1 Protein 2e-94 68

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
hfeA YP_248077.1 periplasmic chelated iron binding protein BAC0439 Protein 2e-102 74
hfeA YP_248077.1 periplasmic chelated iron binding protein BAC0349 Protein 1e-94 68

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
hfeA YP_248077.1 periplasmic chelated iron binding protein VFG0525 Protein 1e-94 68