Gene Information

Name : hfeB (NTHI0479)
Accession : YP_248076.1
Strain : Haemophilus influenzae 86-028NP
Genome accession: NC_007146
Putative virulence/resistance : Virulence
Product : ABC-type chelated iron transport system, ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG1121
EC number : -
Position : 453829 - 454749 bp
Length : 921 bp
Strand : -
Note : Similar to: HI0361, Y361_HAEIN

DNA sequence : 
ATGGACTCTTTCTCGACATCAATTTGGGTTAATGATGTAACTGTTCGTTACAACAATGGTCATACTGCTATTCACAATAT
GACGTTCTCACTCAATAGTGGAACTATTTGTGCGTTAGTTGGCGTGAATGGAAGTGGCAAGTCCACATTATTTAAAAGCA
TAATGGGGCTTGTAAAGCCACAACAAGGCGAAATTAAACTTTGTGATTTGCCAATTTCCCAAGCACTGAAACGTAATTTG
GTTGCTTATGTACCACAATCAGAAGAAGTGGACTGGCAATTTCCAGTATCAGTGTATGATGTCGTGATGATGGGACGTTA
TGGGTATATGAATTTTCTTCGTATCCCCAAAGCGATTGATAAACAAAAAGTTCAAGAGGCGATGCAGCGAGTAAATATTG
AACATCTTGCGCATCGTCAAATTGGCGAGTTATCTGGCGGGCAGAAAAAACGCGTGTTTTTAGCCCGCGCTTTAGCACAA
CAAAGTCCCATTATTTTATTAGATGAACCTTTTACTGGCGTTGATGTGAAAACTGAAAATGCCATTGTTGATCTTCTTCA
ACAGCTTCGAGAAGAAGGTCATCTTATTCTTGTTTCAACCCATAACTTAGGTTCTGTTCCTGATTTTTGTGATCAAGTGG
TAATGATTAATCGCACAGTTATCGCCGCAGGAAAAACAGAAAACACCTTTAACCAACATAATTTGGAAATTGTATTTGGT
GGGGTATTACGTCATATTAAATTATTGGGCGAAAATTTACATAATGATGAAGATAAACGTTCTGTTACTGTCTTAACAGA
TGATGAAAAAGCCGTTGTATTCTATGGCGAAACTAAGCAAGATCCACCTGCGCCAACAACACAAAATTGTCATTTTGAAG
ATTGTCCTTATAAAAGTGCGGTTAAAAATAAGAGGGATTAG

Protein sequence : 
MDSFSTSIWVNDVTVRYNNGHTAIHNMTFSLNSGTICALVGVNGSGKSTLFKSIMGLVKPQQGEIKLCDLPISQALKRNL
VAYVPQSEEVDWQFPVSVYDVVMMGRYGYMNFLRIPKAIDKQKVQEAMQRVNIEHLAHRQIGELSGGQKKRVFLARALAQ
QSPIILLDEPFTGVDVKTENAIVDLLQQLREEGHLILVSTHNLGSVPDFCDQVVMINRTVIAAGKTENTFNQHNLEIVFG
GVLRHIKLLGENLHNDEDKRSVTVLTDDEKAVVFYGETKQDPPAPTTQNCHFEDCPYKSAVKNKRD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
sitB NP_461783.1 ATP-binding protein Virulence SPI-1 Protein 6e-73 63
sitB NP_457256.1 Iron transport protein, ATP-binding component Virulence SPI-1 Protein 2e-73 63
sitB NP_806465.1 iron ABC transporter ATP-binding protein Virulence SPI-1 Protein 2e-73 63
sitB AAD41066.1 SitB Virulence centisome 63 pathogenicity island Protein 4e-73 63
sitB YP_217782.1 iron transporter: fur regulated Virulence SPI-1 Protein 1e-72 62

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
hfeB YP_248076.1 ABC-type chelated iron transport system, ATPase BAC0440 Protein 1e-98 72
hfeB YP_248076.1 ABC-type chelated iron transport system, ATPase BAC0350 Protein 3e-73 63
hfeB YP_248076.1 ABC-type chelated iron transport system, ATPase BAC0400 Protein 4e-44 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
hfeB YP_248076.1 ABC-type chelated iron transport system, ATPase VFG0526 Protein 2e-73 63