Gene Information

Name : hsdM2 (NTHI0314)
Accession : YP_247933.1
Strain : Haemophilus influenzae 86-028NP
Genome accession: NC_007146
Putative virulence/resistance : Unknown
Product : type I restriction-modification system methyltransferase subunit
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0286
EC number : -
Position : 293988 - 295532 bp
Length : 1545 bp
Strand : +
Note : M protein; Similar to: HI1287, T1MP_ECOLI

DNA sequence :
ATGGCTGCTGCAATTCAACAACGTGCCGAACTTCAACGTCGTATTTGGCAAATTGCTAATGATGTGCGAGGCTCAGTCGA
TGGCTGGGATTTCAAACAATATGTACTTGGCACACTTTTTTACCGTTTTATTAGCGAAAATTTTGCCAATTACATTGAAG
CAGGCGATGAAAGCGTAAATTATGCCCAATTACCTGATGAAATCATTACCCCAGACATTAAAACAGATGCCATTAAAACG
AAAGGCTACTTTATTTACCCAAGCCAATTATTTAAGAATGTTGCGGCTAATGCTGGCAACAATCCTAATTTGAATACTGA
TTTAAAACAGATTTTTACTGATATTGAAAACTCAGCGACGGGCTTTCCGTCTGAACAAGATATTAAAGGCTTATTTGCCG
ATTTTGATACCACCAGCAATCGCTTAGGCAATACCGTAAAAGATAAAAACGACCGCTTAACGGCTGTTTTGAAAGGCGTG
GCTGAACTTGATTTTGGCAAATTTGAAGATAACCACATTGATTTATTTGGCGATGCATACGAATATCTTATTTCTAACTA
TGCTGCCAATGCAGGCAAATCTGGTGGTGAATTTTTTACCCCACAAAGTGTTTCCAAACTCATTGCTCAAATTGCAATGC
ACGGGCAAACCTCGGTCAATAAAATTTATGATCCCGCAGCAGGTTCTGGCTCACTTTTGCTTCAAGCCAAAAAACAATTT
GATGAACATATTATTGAAGAAGGCTTTTTCGGGCAGGAAATTAACCATACCACATATAACCTTGCCCGTATGAATATGTT
TTTGCATAACATCAACTACGACAAATTTGATATTGCTTTAGGCAACACCTTAATGGAACCACAATTTGGCGATGATAAAC
CTTTCGATGCCATCGTTTCTAACCCACCTTACTCCGTGAAATGGGCTGGCTCCGACAATCCAACACTGATTAACGATGAA
CGATTTGCCCCCGCAGGCGTGCTTGCACCAAAATCCAAAGCGGATTTTGCCTTTATTTTACACGCATTAAGCTATCTTTC
AGGCAAAGGCAGGGCGGCGATTGTCTCCTTCCCAGGCATTTTTTATCGTGGCGGTGCGGAGCAAAAAATTCGTCAATATT
TGGTGGATAATAATTTTGTGGAAACCGTGATTGCCCTTGCACCTAATCTATTCTACGGCACCAGTATTGCCGTAAATATT
TTGGTTTTGTCCAAGCACAAACCAAATACCCAAACTCAATTTATCGATGCCAGCGGTTTATTTAAATCTGCCACCAATAA
CAACATTTTAGAAGAGGAACATATTGAGCAAATTCTCAAACTGTTTGCCAATAAAGAAGATGTGCCGCATTTGGCAAAAT
CCGTATCCTTTGAAGAAATCGCCCAAAATGACCACAACCTTGCAGTAAGTTCGTATGTGGAACAAAAAGATACCCGAGAA
GTAATTAATATTGATGAACTCAATGCTCAAATTCGTGAAACTGTTACCAATATTGACCGCTTGCGTGCCGAGATTGATAA
GATTGTTGCAGAAATTGAGGGGTAA

Protein sequence :
MAAAIQQRAELQRRIWQIANDVRGSVDGWDFKQYVLGTLFYRFISENFANYIEAGDESVNYAQLPDEIITPDIKTDAIKT
KGYFIYPSQLFKNVAANAGNNPNLNTDLKQIFTDIENSATGFPSEQDIKGLFADFDTTSNRLGNTVKDKNDRLTAVLKGV
AELDFGKFEDNHIDLFGDAYEYLISNYAANAGKSGGEFFTPQSVSKLIAQIAMHGQTSVNKIYDPAAGSGSLLLQAKKQF
DEHIIEEGFFGQEINHTTYNLARMNMFLHNINYDKFDIALGNTLMEPQFGDDKPFDAIVSNPPYSVKWAGSDNPTLINDE
RFAPAGVLAPKSKADFAFILHALSYLSGKGRAAIVSFPGIFYRGGAEQKIRQYLVDNNFVETVIALAPNLFYGTSIAVNI
LVLSKHKPNTQTQFIDASGLFKSATNNNILEEEHIEQILKLFANKEDVPHLAKSVSFEEIAQNDHNLAVSSYVEQKDTRE
VINIDELNAQIRETVTNIDRLRAEIDKIVAEIEG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hsdM YP_493119.1 type I restriction-modification system, M subunit Not tested vSa¥á Protein 8e-95 42
hsdM2 YP_186690.1 type I restriction-modification system, M subunit Not tested vSa¥â Protein 7e-95 42
hsdM NP_373642.1 type I site-specific deoxyribonuclease LldI subunit HsdM Not tested vSa¥á Protein 2e-94 42
SAMSHR1132_03780 YP_005324900.1 putative type I restriction enzyme modification protein Not tested vSa¥á Protein 4e-94 42
SAS0394 YP_042520.1 restriction enzyme modification protein Not tested vSa¥á Protein 1e-94 42
hsdM NP_370955.1 type I site-specific deoxyribonuclease LldI chain Not tested vSa¥á Protein 3e-94 42
hsdM NP_645209.1 type I site-specific deoxyribonuclease LldI chain hsdM Not tested vSa¥á Protein 1e-94 42
SAKOR_00415 YP_008490599.1 Type I restriction-modification system methylation subunit Not tested vSa¥á Protein 1e-94 42
SAR0433 YP_039884.1 type I restriction enzyme modification protein Not tested vSa¥á Protein 2e-94 42
hsdM1 YP_185366.1 type I restriction-modification system, M subunit Not tested vSa¥á Protein 8e-95 42
hsdM YP_001331432.1 type I restriction-modification system, methyltransferase subunit Not tested vSa¥á Protein 8e-95 42
SAR1899 YP_041281.1 type I restriction modification system modification protein Not tested vSa¥â Protein 2e-93 42
SSP0053 YP_300143.1 type I restriction-modification system methyltransferase subunit Not tested SCC15305cap Protein 5e-95 42
SAMSHR1132_16570 YP_005326167.1 restriction-modification system, M subunit Not tested vSa¥â Protein 3e-94 42
SAKOR_01757 YP_008491945.1 Type I restriction-modification system methylation subunit Not tested vSa¥â Protein 7e-95 42
hsdM YP_001332734.1 type I restriction-modification system, methyltransferase subunit Not tested vSa¥â Protein 5e-95 42
hsdM YP_494443.1 type I restriction-modification system, M subunit Not tested vSa¥â Protein 5e-95 42
SAV1808 NP_372332.1 type I restriction enzyme EcoR124II M protein Not tested vSa¥â Protein 2e-94 41
SA1626 NP_374915.1 hypothetical protein Not tested vSa¥â Protein 2e-94 41
ORF6 BAC22943.1 - Not tested etd PI Protein 4e-94 41
SAS1732 YP_043848.1 type I restriction enzyme modification protein Not tested vSa¥â Protein 2e-94 41
hsdM NP_646568.1 hypothetical protein Not tested vSa¥â Protein 2e-94 41