Gene Information

Name : nanE (NTHI0231)
Accession : YP_247865.1
Strain : Haemophilus influenzae 86-028NP
Genome accession: NC_007146
Putative virulence/resistance : Virulence
Product : N-acetylmannosamine-6-phosphate 2-epimerase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG3010
EC number : 5.1.3.9
Position : 222671 - 223357 bp
Length : 687 bp
Strand : -
Note : ManNAc-6-P epimerase; Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate

DNA sequence : 
ATGTCTAAATTATCTTATCAAGAAGTACTTTCTCAAATTCAATATGGTCTCATTTCTTCTTGCCAACCTGTCGATGATGG
CCCAATGGATAAACCTGAAATCGTTTCTGCTATGGCTCAGGCTTCAGTTATGGGCGGCGCTTCTGGCTTACGTATTGAGG
GTGTTGATAACCTTAAAGCAACCCGTCCTTTTGTGAATGTTCCGATTATCGGAATTGTAAAACGTGATTTGCCTGATAGT
CCCGTGCGTATTACGCCGTTTTTACAAGATATTGAAGATCTAGCCAATGCAGGTGCGGATATTATTGCAGTAGATGGCAC
GAGCCGCCCACGTCCTGTGGATATTGAAAGTGCGGTGAAAAAAATCCACGAAATGGGCTGTTTGGCAATGGCAGATTGTT
CTAATTTAGAAGAAGGCTTGTATTGTAAAGCGCTTGGTTTTGATATTGTCGGCAGTACGATGTCGGGTTATACAGGTGGC
GCAGTGCCAGAAGAACCAGATTATCAATTAGTGAAAGATTTAAAATCAGCGGGTTGTTTTGTGATGGCTGAGGGGCGTTA
TAACACACCAGAATTGGCAAAAGTGGCAATTGAAATTGGTGCAGATTGCGTGACTGTAGGTTCAGCCTTAACTCGTCTTG
AACATATTGTGAGTTGGTTTGCTAATTCAGTGAAATCTGCAAGATAG

Protein sequence : 
MSKLSYQEVLSQIQYGLISSCQPVDDGPMDKPEIVSAMAQASVMGGASGLRIEGVDNLKATRPFVNVPIIGIVKRDLPDS
PVRITPFLQDIEDLANAGADIIAVDGTSRPRPVDIESAVKKIHEMGCLAMADCSNLEEGLYCKALGFDIVGSTMSGYTGG
AVPEEPDYQLVKDLKSAGCFVMAEGRYNTPELAKVAIEIGADCVTVGSALTRLEHIVSWFANSVKSAR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0395_A1378 YP_001217321.1 N-acetylmannosamine-6-phosphate 2-epimerase Not tested VPI-2 Protein 1e-52 58
VC1781 NP_231416.1 N-acetylmannosamine-6-phosphate 2-epimerase Not tested VPI-2 Protein 6e-53 58
nanE ACA01846.1 N-acetylmannosamine-6-phosphate epimerase Not tested VPI-2 Protein 9e-53 58

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
nanE YP_247865.1 N-acetylmannosamine-6-phosphate 2-epimerase VFG1114 Protein 2e-53 58