Gene Information

Name : pepA (NTHI2013)
Accession : YP_249420.1
Strain : Haemophilus influenzae 86-028NP
Genome accession: NC_007146
Putative virulence/resistance : Unknown
Product : leucyl aminopeptidase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0260
EC number : 3.4.11.1
Position : 1866632 - 1868107 bp
Length : 1476 bp
Strand : +
Note : aminopeptidase A; leucine aminopeptidase; LAP; Leucyl aminopeptidase; catalyzes the removal of N-terminal amino acids preferably leucine from various peptides

DNA sequence :
ATGAAATATCAAGCAAAAAATACCGCACTTTCTCAAGCCACTGATTGCATTGTTTTAGGCATCTATGAAAATAATAAATT
TTCAAAAAGTTTTAATGAAATCGATCAATTAACCCAAGGTTATTTAAACGATTTAGTGAAATCAGGTGAGCTCACTGGCA
AATTAGCCCAAACCATTTTACTTCGTGATCTTCAAGGTTTATCTGCTAAACGCCTATTAATCGTTGGCTGTGGCAAAAAA
GGAGAACTCACAGAGCGTCAATATAAACAAATCATCCAAGCTGTATTAAAGACACTAAAAGAAACCAACACGCGTGAAGT
CATTTCTTATTTAACTGAAATTGAATTAAAAGATCGCGATCTTTATTGGAATATCCGCTTTGCCATTGAAACGATTGAAC
ACACCAATTATCAATTTGATCATTTCAAATCTCAAAAAGCAGAAACCTCTGTTTTAGAATCTTTCATCTTTAATACGGAT
TGTAATCAAGCACAACAAGCTATTTCTCACGCCAATGCCATTAGCTCAGGCATAAAAGCAGCACGTGACATCGCAAATAT
GCCACCAAATATTTGTAATCCAGCTTATCTTGCTGAGCAAGCAAAAAATTTAGCAGAAAATTCTACCGCACTTTCATTGA
AAGTTGTGGATGAAGAAGAAATGGCTAAACTTGGAATGAACGCTTATCTTGCCGTCTCAAAAGGCTCTGAAAACCGTGCT
TATATGTCTGTTTTAACATTCAATAATGCGCCAGATAAAAACGCCAAACCCATTGTACTTGTAGGCAAAGGATTAACCTT
TGATGCTGGCGGTATTTCACTTAAACCCGCCGCAGATATGGATGAAATGAAATATGATATGTGCGGTGCAGCCTCTGTCT
TCGGCACAATGAAAGCCATTGCACAGTTGAACTTACCATTAAACGTTATTGGTGTTTTAGCAGGTTGTGAAAATCTGCCA
GATGGCAATGCTTATCGCCCAGGCGATATTCTTACCACTATGAATGGTTTAACTGTAGAAGTTCTTAATACTGATGCAGA
AGGTCGATTAGTGCTTTGTGATGCACTTACTTATGTTGAGCGTTTTGAACCTGAGCTTGTTATTGATGTTGCAACCTTGA
CTGGTGCTTGTGTGGTTGCACTAGGGCAACACAATAGCGGCTTAGTTTCTACAGATAACAATCTTGCCAATGCACTACTC
CAAGCCGCAACAGAAACCACTGACAAAGCGTGGCGTTTACCATTAAGCGAAGAATATCAAGAGCAACTTAAATCGCCTTT
CGCCGACCTTGCCAACATTGGTGGTCGCTGGGGTGGCGCAATTACAGCGGGTGCATTTTTGTCTAACTTCACGAAAAAAT
ATCGCTGGGCACATTTAGACATCGCAGGCACTGCTTGGTTACAAGGCGCAAATAAAGGTGCAACAGGTCGCCCTGTTTCG
CTATTAACCCAATTTTTGATTAATCAAGTTAAATAA

Protein sequence :
MKYQAKNTALSQATDCIVLGIYENNKFSKSFNEIDQLTQGYLNDLVKSGELTGKLAQTILLRDLQGLSAKRLLIVGCGKK
GELTERQYKQIIQAVLKTLKETNTREVISYLTEIELKDRDLYWNIRFAIETIEHTNYQFDHFKSQKAETSVLESFIFNTD
CNQAQQAISHANAISSGIKAARDIANMPPNICNPAYLAEQAKNLAENSTALSLKVVDEEEMAKLGMNAYLAVSKGSENRA
YMSVLTFNNAPDKNAKPIVLVGKGLTFDAGGISLKPAADMDEMKYDMCGAASVFGTMKAIAQLNLPLNVIGVLAGCENLP
DGNAYRPGDILTTMNGLTVEVLNTDAEGRLVLCDALTYVERFEPELVIDVATLTGACVVALGQHNSGLVSTDNNLANALL
QAATETTDKAWRLPLSEEYQEQLKSPFADLANIGGRWGGAITAGAFLSNFTKKYRWAHLDIAGTAWLQGANKGATGRPVS
LLTQFLINQVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00295 YP_008207760.1 Leucyl aminopeptidase Not tested AbaR25 Protein 1e-90 49
BJAB0868_00299 YP_008211625.1 Leucyl aminopeptidase Not tested AbaR26 Protein 1e-90 49