Gene Information

Name : serS (NTHI0200)
Accession : YP_247837.1
Strain : Haemophilus influenzae 86-028NP
Genome accession: NC_007146
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 183462 - 184751 bp
Length : 1290 bp
Strand : +
Note : Serine--tRNA ligase; SerRS; catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGATCGATCCAAATTTACTCCGTAATAATTTAGCAGAAGTCGCAGAAAAATTAAAAGTAAAACGCAACTTTATGCTTGA
TACGGAAAAACTCACCGCGTTAGAAGATCAGCGCAAAAACTTACAAGTCACTACCGAAAACTTACAAGCGGAACGTAATG
CTCGTTCCAAAGCCATTGGTGCTGCTAAAGTGCGTGGTGAAGATATCGCACCATTATTGGCAGAAATGGATGATATGGGC
AATCAATTGACTGAAGCAAAAGCACAATTAGATGCGGTACTTGCAGAAATCAATCAAATTGCATTAAGTATTCCAAATCT
ACCCGCAGACGAAGTGCCATTAGGCAAAGATGACACAGAAAATAAAGAAATCTTACGTTGGGGTACACCGCATACATTTG
ATTTTGAAGTGAAAGATCATATCACTTTGGGTGAAGAAGCAAATGGCTTAGATTTTGCTGCTGGGGCTAAATTAGCTGGT
GCGCGTTTTGCCGTAATGAAAGGTCAAATCGCTAAAATGCACCGCGCATTGGCACAATTCATGTTAGATCTTCATACTGA
ACAACACGGCTATTTAGAAACCTATGTGCCTTATTTAGTAAATCACGCAACACTTTATGGTACAGGGCAATTACCAAAAT
TCGGGGAAGATTTATTCCATACTTTAGCCTTAGAAGGCGAACAACCTTACGCATTAATTCCAACCGCAGAAGTGCCCGTC
ACTAATTTAGTGCGTGATGTAATTATTGATGAAGCAGAATTACCAATAAAAATGACCGCACATACGCCATGTTTCCGTTC
TGAAGCTGGCTCTTACGGTCGTGATACTCGTGGTTTAATTCGTATGCACCAATTTGATAAAGTAGAAATGGTACAAATCG
TTGATCCAGATAAATCAATGGAAGCACTTGAAGAATTAACAGGTCATGCGGAAAAAGTATTGCAATTATTAAATTTACCA
TACCGTAAAGTTTTACTTTGCACAGGCGATATGGGCTTTGGTTCTTGCAAAACTTACGATTTAGAAGTTTGGCTGCCTGC
ACAAAATACTTATCGAGAAATTTCTTCTTGCTCAAATATGTGGGATTTCCAAGCTCGCCGTATGCAAGCTCGCTGTAAAG
CAAAAGGCGATAAGAAAACTCGCTTAGTGCACACATTAAATGGTTCAGGCTTAGCGGTTGGTCGTACTTTAGTGGCTGTA
CTTGAAAACTATCAAAATGCCGATGGTTCAATTACCGTGCCAGAAGAGCTACGTCCATATATGGGCGGATTAGACGTTAT
CGGAAAATAA

Protein sequence :
MIDPNLLRNNLAEVAEKLKVKRNFMLDTEKLTALEDQRKNLQVTTENLQAERNARSKAIGAAKVRGEDIAPLLAEMDDMG
NQLTEAKAQLDAVLAEINQIALSIPNLPADEVPLGKDDTENKEILRWGTPHTFDFEVKDHITLGEEANGLDFAAGAKLAG
ARFAVMKGQIAKMHRALAQFMLDLHTEQHGYLETYVPYLVNHATLYGTGQLPKFGEDLFHTLALEGEQPYALIPTAEVPV
TNLVRDVIIDEAELPIKMTAHTPCFRSEAGSYGRDTRGLIRMHQFDKVEMVQIVDPDKSMEALEELTGHAEKVLQLLNLP
YRKVLLCTGDMGFGSCKTYDLEVWLPAQNTYREISSCSNMWDFQARRMQARCKAKGDKKTRLVHTLNGSGLAVGRTLVAV
LENYQNADGSITVPEELRPYMGGLDVIGK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 5e-97 53