Gene Information

Name : siaB (NTHI1891)
Accession : YP_249309.1
Strain : Haemophilus influenzae 86-028NP
Genome accession: NC_007146
Putative virulence/resistance : Virulence
Product : acylneuraminate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1083
EC number : 2.7.7.43
Position : 1728850 - 1729524 bp
Length : 675 bp
Strand : -
Note : CMP-N-acetylneuraminic acid synthetase; CMP-NeuNAc synthetase; CMP-sialic acid synthetase; Similar to: HI1279, NEUA_HAEIN

DNA sequence :
ATGACAAGAATTGCAATTATTCCTGCGAGAGCGGGTTCTAAAGGAATTAAAGACAAAAATTTACAGCTTGTGGGTGGTGT
TTCTTTGGTGGGGCGTGCGATTTTGGCAGCGCAAGAATCGGGTATGTTTGATCAAATTGTGGTGACATCAGACGGTGAAA
ATATTTTAAAAGAAGCCACAAAATACGGCGCAAAACCAGTGGCACGCCCTGAAAGTTTGGCGCAAAGTGATACACGCACC
ATTGATGCAATTTTGCATTGCTTAGAAACACTTAATATTTCACAAGGCACCGCTGCACTTTTGCAACCAACCAGCCCATT
GCGTAATGCTTTAGATATTCGTAATGCAATGGAAATTTTCCTTGGCGGCAAATATAAGTCAGTGGTTTCCGCTTGCGAAT
GTGAGCATCATCCTTATAAATCCTTCACTTTAGAAGGTACCGAAGTTCAGCCTATTCACGAATTAACGGATTTTGAAGCC
CCTCGTCAAAAATTACCCAAATCTTATCGTGCAAATGGCGCAATTTATATTAATGACATCGAAAGTCTCTTTGAAGAAAA
ACGCTTTTTTATTGCGCCAATGCGTTTTTATTTAATGCCAACTTATCGTTCCATTGATATTGACTCCACACTTGATTTGC
AATTAGCCGAAAGTTTAATTTCAAAAGAATTCTAA

Protein sequence :
MTRIAIIPARAGSKGIKDKNLQLVGGVSLVGRAILAAQESGMFDQIVVTSDGENILKEATKYGAKPVARPESLAQSDTRT
IDAILHCLETLNISQGTAALLQPTSPLRNALDIRNAMEIFLGGKYKSVVSACECEHHPYKSFTLEGTEVQPIHELTDFEA
PRQKLPKSYRANGAIYINDIESLFEEKRFFIAPMRFYLMPTYRSIDIDSTLDLQLAESLISKEF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
siaB NP_273133.1 polysialic acid capsule biosynthesis protein SiaB Not tested IHT-A Protein 3e-42 49

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
siaB YP_249309.1 acylneuraminate cytidylyltransferase VFG0253 Protein 1e-42 49