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Name : hsdR3 (NTHI1843) Accession : YP_249269.1 Strain : Haemophilus influenzae 86-028NP Genome accession: NC_007146 Putative virulence/resistance : Unknown Product : type I restriction enzyme HindVIIP R protein Function : - COG functional category : V : Defense mechanisms COG ID : COG0610 EC number : 3.1.21.3 Position : 1694179 - 1697346 bp Length : 3168 bp Strand : + Note : Similar to: HI1285, T1RH_HAEIN DNA sequence : ATGCTCAACGAAAACGACATCGAACAACTCACCCTTCAACGCCTGCAATCCCTCGGTTGGGAATATCGCTATGGTAAAGA TTTGCCTGTTCATGAGGGCGAATTTTCCCGTGGCAATTTGAGCGGTGTAGTTTTTATTGAGCAACTGCGTGAGGCGGTGC GTAAACTTAATCCGCAGCTGCCTGAAAGTGCGGTTGATTCTGTGGTGAAATCCGCGACAAAAAGCGATATTGGCGACTTG GTTGTGCGTAATCAGACGTTTTATAAATTGTTGCGTGATGGTGTACGGGTAGAATATCAAGATGATGGTGAGCAGAAAAT CGAGATGGCGCGTTTGGTGGATTTTGAGCATGGGGAAAACAACCGCTTTGTCGCCGTCAATCAGCTGGAAATCCGCAGCC GTAAAGGAGGTAAACGGATTCCCGATATTATCGGCTTTGTAAATGGGCTGCCTTTGGTGGTATTTGAGCTCAAAAATCCG CTGCGTGAATCGGCGGATTTATTGCAGGCGTTTAATCAGTTTGAAACCTATAAAGATGAAATTGCCGAGCTGTTTGTTTA CAACCAAGCCCTGATTATTTCAGACGGCATTGCCGCCCGTTTGGGTTCGCTTTCGGCAGATTTTCAACGCTTTACGCCGT GGAAAGTGGTCGATGAAAAAAATAAAAGCGTGCGGTTATATTTTGACGATGAGTTGCAAAGCCTGCTCAATGGCTTAATG CAGCCTGAGGATTTATTGGACTATATCCGCTATTTCGTCTTGTTTGAACGGGATTCCGTTGGCAAAACCATTAAAAAAAT CGCGGCATACCATCAATATTACGGCGTAAATGAAGCAGTAGAATCCACGATTTTTGCCACAAGCGAGCAAGGCGATAAAC GCATCGGTGTGATGTGGCACACGCAGGGTTCGGGTAAGTCGATTTCGATGCTGTTTTATGCAGGCAAACTGCTTGCACAG CCTGAATTGAAAAATCCTACCATTGTAGTGGTTACCGACCGCAACGATTTAGATGGTCAGCTTTTCCAAACTTTTTCTTC AGGCAAAGATTTAATCAAACAAACACCGCAGCAAGTAGAAGACCGTGATCAACTGCGCCAACTGCTCGCACAAAATGAAG TCGGCGGCGTGTTTTTTACTACGATTCAGAAATTCGCCCTAAATGAGGAAGAAAGCCGCTTCCCTATTTTAAATGAGCGC AACAATATTATTGTGATCAGCGATGAGGCTCACCGCAGCCAATATGGCTTTACGCAAAAGCTGCATAACGGCAAGTTTCA GACAGGTTATGCTCGCCATTTGCGTGATGCTTTACCTAATGCCTCGTTTATTGGTTTTACAGGTACGCCAATTAGCCTTG AAGATAAGGACACGCAAGATGTGTTCGGTCGTTATGTGTCCATTTATGACTTGCAAGATGCGGTGGAAGATGGCGCAACC GTGCCGATTGTGTATGAAGCACGCCAAATCAAGCTAGCGGAGAATGCTAATCACGATGAATTATTTGCAGAAATTGATGA ACTGCTGGAAGGCGAAGAAAACCCGAAATTACGCTTGCGAGAAAAATTGCTCGGCTCAGAAGCTCGATTGCATGATTTAG CGATCGATTTTGTGCAACATTTTGCAAAACGCAATGAAGTGGTGGACAGCAAAGCGATGATGGTGGTTTCCAGCCGTCAG ATTTGCGTGGATTTGTATAATCAGATCATCGCTCTGCACCCTGAATGGCATTCGGACAATATTAACGAAGGGGCGATTAA AATTGTGATGACAGGTTCTGCTTCCGATGCGTCTGAAATGCAGAAACACGTTTACAGTAAACAGGAAAAGCAAACGTTAG AACGTCGTTTTAAAGACCCGAACGATCCGCTGAAAGTGGTGATTGTGCGTGATATGTGGCTGACAGGCTTTGATGCACCG TGCTGTAACACTATGTATCTTGATAAGCCAATGAAAGGGCATAACCTAATGCAAGCCATCGCACGAGTAAACCGTGTATT CCGCAATAAAAGCCGAGAAAATGGCGGCTTGATTGTGGATTATGTAGGCATTGCTGACGAGCTCGAAAAAGCCACTCGGC AATATACAAACTCACAAGGCAAGGGCAAACTGGCTGATAGCGTGATTGATGTATTCTTTAAAATGAAAGAGCATTTAGAA GTTATCCGCAGCCTGTTTGCAACGCCAGTTGAGGGGAAAACCTTTGATGTTCAGGCTGCCTTAGAAAAAGATAATCCGAA TGATCTTTTGATGGCGATTCGTTTTGCCGCCAACCATATTTTAAGCCTTGATCAATTATCGTTTGATGGCAAAGCGCACG AGCAGCATTGGTTTAATAAAAAAGAAACCGAGCCACGCAAAAAAGCCTTTTTGAAAACGGCAGGCTTGGTAAAAAAAGGC TATATGCTGTGCGGCACATTGGCTGAAGTTGAGCCGTATAACCAAGAAATCGCCTTTTATGATGCCGTACGGGCAATTTT AACTAAACGTGAACAAAAAGGCACAGGCACAAATGAAAGACAGATTTTATTGAAAAAATTGGTCAATCAAACTGTGTATT CTGAAGGCGTGATTGATTTATTCGATCTGCTAGAAAAACCACAACCACAAATCAGTTTGCTTTCCGAGGAATTTTTACAA ACTGTAAAAAATAGCCCAACTAAAAATTTATGGGTTAGCGCGATGGAGCGTTATTTGGCAAGTGAAATTAAAGTTAAATC AGGCACAAACTTAACCTTGCAAAAAGATTTTGAACGGCGTTTGAAGGAAGCATTGAATCAATACCACAATCACAATTTGA CTGTGGTAGAGATTTTGGACGAACTCTTTAAAATGAGCCAAGATTTCCAAGAACGTTTAGCATTAGGGAAAAAACTAGGA TTAACCAAGGAAGAACTAGCCTTCTATGAAGCTCTATCTCAAAATCAAAGTGCAAAAGATTTGATGGGTGATGAAGTGCT TTCTAAACTGGCGAAAGAAATCACGGAAACACTTAGAAAATCGGTCACAATCGACTGGCAGTACAAAGAAGCGGTGCGGG CAAGAATTAGATTACTCGTTCGACGTGCCTTACAAAAATATAAATACCCGCCTGATAAACAGGAAGAAGCGGTAACTTAT GTGATTAAACAAGCTGAAGAAATTGCTGAGGATTTAACTGGTTTATAA Protein sequence : MLNENDIEQLTLQRLQSLGWEYRYGKDLPVHEGEFSRGNLSGVVFIEQLREAVRKLNPQLPESAVDSVVKSATKSDIGDL VVRNQTFYKLLRDGVRVEYQDDGEQKIEMARLVDFEHGENNRFVAVNQLEIRSRKGGKRIPDIIGFVNGLPLVVFELKNP LRESADLLQAFNQFETYKDEIAELFVYNQALIISDGIAARLGSLSADFQRFTPWKVVDEKNKSVRLYFDDELQSLLNGLM QPEDLLDYIRYFVLFERDSVGKTIKKIAAYHQYYGVNEAVESTIFATSEQGDKRIGVMWHTQGSGKSISMLFYAGKLLAQ PELKNPTIVVVTDRNDLDGQLFQTFSSGKDLIKQTPQQVEDRDQLRQLLAQNEVGGVFFTTIQKFALNEEESRFPILNER NNIIVISDEAHRSQYGFTQKLHNGKFQTGYARHLRDALPNASFIGFTGTPISLEDKDTQDVFGRYVSIYDLQDAVEDGAT VPIVYEARQIKLAENANHDELFAEIDELLEGEENPKLRLREKLLGSEARLHDLAIDFVQHFAKRNEVVDSKAMMVVSSRQ ICVDLYNQIIALHPEWHSDNINEGAIKIVMTGSASDASEMQKHVYSKQEKQTLERRFKDPNDPLKVVIVRDMWLTGFDAP CCNTMYLDKPMKGHNLMQAIARVNRVFRNKSRENGGLIVDYVGIADELEKATRQYTNSQGKGKLADSVIDVFFKMKEHLE VIRSLFATPVEGKTFDVQAALEKDNPNDLLMAIRFAANHILSLDQLSFDGKAHEQHWFNKKETEPRKKAFLKTAGLVKKG YMLCGTLAEVEPYNQEIAFYDAVRAILTKREQKGTGTNERQILLKKLVNQTVYSEGVIDLFDLLEKPQPQISLLSEEFLQ TVKNSPTKNLWVSAMERYLASEIKVKSGTNLTLQKDFERRLKEALNQYHNHNLTVVEILDELFKMSQDFQERLALGKKLG LTKEELAFYEALSQNQSAKDLMGDEVLSKLAKEITETLRKSVTIDWQYKEAVRARIRLLVRRALQKYKYPPDKQEEAVTY VIKQAEEIAEDLTGL |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| api52 | CAF28526.1 | hsdr-like Type I restriction enzyme | Not tested | YAPI | Protein | 0.0 | 49 |
| hsdR | YP_251977.1 | type I restriction-modification system restriction subunit | Not tested | SCCmec | Protein | 0.0 | 42 |
| hsdR | BAH57699.1 | type I restriction-modification system endonuclease homologue | Not tested | Type-VII SCCmec | Protein | 0.0 | 42 |
| hsdR | BAD24840.1 | type I restriction-modification system endonuclease homologue | Not tested | Type-V SCCmec | Protein | 0.0 | 42 |
