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Name : pykA (NTHI1479) Accession : YP_248953.1 Strain : Haemophilus influenzae 86-028NP Genome accession: NC_007146 Putative virulence/resistance : Virulence Product : pyruvate kinase Function : - COG functional category : G : Carbohydrate transport and metabolism COG ID : COG0469 EC number : 2.7.1.40 Position : 1406521 - 1407957 bp Length : 1437 bp Strand : - Note : PK; catalyzes the formation of phosphoenolpyruvate from pyruvate DNA sequence : ATGTCTAGAAGACTAAGAAGAACGAAGATTGTATGTACTATGGGCCCATCAACTGACCGTGATAACAATCTTGAAAAAAT TATCGCAGCGGGCGCAAACGTAGTTCGTATGAACTTCTCTCACGGTACACCTGATGACCATATCGGACGTGCTGAACGTG TACGTTCTATTGCGAAAAAATTAGGTAAAACCGTGGCAATCTTAGGTGATTTACAAGGTCCTAAAATTCGTGTTTCTACT TTTAAAGACGGTAAAATTTTCTTAAACGTTGGCGATAAATTCATTCTTGATGCAGAATTACCAAAAGGCGAAGGCACTCA AGAATCCGTTGGTTTAGACTATAAAACGCTTCCTCAAGATGTTGTGCCGGGCGATATTCTTTTATTAGATGATGGCCGTG TTCAATTAAAAGTATTATCAACTGATGGTGCAAAAGTTTTCACTGAAGTTACTGTTGGTGGTCCATTATCAAATAATAAA GGTATCAATAAATTAGGTGGCGGTTTATCTGCGGATGCCCTAACAGAAAAAGATAAAGCCGACATTATTACCGCTGCACG CATTGGTGTTGATTTCTTAGCCGTTTCTTTCCCTCGTTCAAGTGCAGATTTAAATTATGCACGTGAACTTGCTCAACAAG CAGGTTTAAATGCAAAAATCGTTGCTAAAGTTGAACGTGCAGAAACCGTTGCTAATGATGAAGCCATGGACGATATTATT TTAGCATCTGATGTAATTATGGTTGCTCGTGGTGACTTAGGCGTAGAAATCGGCGATCCTGAATTAGTCGGTGTACAGAA AAAATTAATTCGTCGTTCACGTCAATTAAATCGTGCTGTAATTACAGCGACTCAAATGATGGAATCAATGATTAGTAACC CAATGCCAACGCGTGCTGAAGTAATGGACGTTGCAAACGCAGTATTAGATGGAACTGATGCAGTTATGCTTTCTGCAGAA ACAGCAGCAGGTCAATATCCTTCTGAAACAGTGGCAGCAATGGCTAGCGTATGTTTAGGTGCAGAAAAAATGCCAAGCAT TAACGTTTCTCGTCACCGTATGGATAAAGAATTTGAAACCATTGAAGAATCTGTTGCGATGTCTGCAATGTATGCAGCAA ACCACATGAAAGGTGTAGCGGCAATCGTCACTTTAACTAGCACAGGCCGTACTCCATTATTAATGTCACGCATTAGCTCT GGCTTACCAATCTTTGCTTTATCTCGTAATCAAGAAACCCTAAACCTTTGTGCACTATACCGCGGTGTAACACCAATTTA TCACGGTGAAGAAAGTCGTACAGAAGCAGGTGCAAAAGCAGCACTTCAATCATTAAAAGAAAAAGGTTATTTATCTACTG GCGATTTAGTACTGGTAACCCAAGGTGGTCAAGGTGCGACACAAACTAACGTATGTCGTACATTAATTGTTGAATAA Protein sequence : MSRRLRRTKIVCTMGPSTDRDNNLEKIIAAGANVVRMNFSHGTPDDHIGRAERVRSIAKKLGKTVAILGDLQGPKIRVST FKDGKIFLNVGDKFILDAELPKGEGTQESVGLDYKTLPQDVVPGDILLLDDGRVQLKVLSTDGAKVFTEVTVGGPLSNNK GINKLGGGLSADALTEKDKADIITAARIGVDFLAVSFPRSSADLNYARELAQQAGLNAKIVAKVERAETVANDEAMDDII LASDVIMVARGDLGVEIGDPELVGVQKKLIRRSRQLNRAVITATQMMESMISNPMPTRAEVMDVANAVLDGTDAVMLSAE TAAGQYPSETVAAMASVCLGAEKMPSINVSRHRMDKEFETIEESVAMSAMYAANHMKGVAAIVTLTSTGRTPLLMSRISS GLPIFALSRNQETLNLCALYRGVTPIYHGEESRTEAGAKAALQSLKEKGYLSTGDLVLVTQGGQGATQTNVCRTLIVE |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| pykA | NP_273151.1 | pyruvate kinase | Not tested | IHT-A | Protein | 9e-78 | 49 |
| pykF | YP_216386.1 | pyruvate kinase | Not tested | SPI-2 | Protein | 3e-55 | 41 |
| pykF | NP_805051.1 | pyruvate kinase | Not tested | SPI-2 | Protein | 3e-55 | 41 |
| STY1744 | NP_456147.1 | pyruvate kinase | Not tested | SPI-2 | Protein | 7e-56 | 41 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| pykA | YP_248953.1 | pyruvate kinase | VFG0479 | Protein | 1e-55 | 41 |
