Gene Information

Name : murD (NTHI1303)
Accession : YP_248797.1
Strain : Haemophilus influenzae 86-028NP
Genome accession: NC_007146
Putative virulence/resistance : Unknown
Product : UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0771
EC number : 6.3.2.9
Position : 1237571 - 1238884 bp
Length : 1314 bp
Strand : +
Note : UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; D-glutamic acid adding enzyme; UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-

DNA sequence :
ATGAATGCCTATCAAAACAAAAATATTACGATCATTGGGCTTGGCAAAACAGGTCTTTCTTGTGTGGATTATCTCTTATC
CCAACAGGCTAATATTCGTGTGATTGATACCCGAAAAAAGCCTACTGGTATTGATAAACTTCCTCAAAATATCCCTCTTC
ATACTGGTAGTTTAAATCAGGAATGGTTACTTGAAAGCGATATGATTGTTATTAGCCCAGGGCTTGCGGTAAAAACACCA
GAAATTCAAACCGCACTTAAAGCGGGAGTGGAAGTAATCGGCGATATTGAATTATTCTGCCGCGCAGCGACAAAGCCAAT
TGTGGGGATTACAGGTTCAAATGGAAAAAGTACTGTTACTACTTTAGTTTATGAAATGGCGAAAGCTGCTGGCGTGAAAG
TTGGTATGGGCGGAAATATTGGGATTCCCGCTTTGTCATTGTTGAATGAAGATTGTGAACTTTATGTACTAGAGCTTTCT
AGTTTTCAGCTTGAGACAACTTATAGCTTAAAAGCTGCGGCTGCGACTGTTTTGAACGTGACTGAAGATCATATGGATCG
CTATATGGATTTAGAAGATTATCGCCAAGCAAAATTACGCATTTATCATAATGCTGAGGTCGGAGTTTTGAATAATGAGG
ATAAGCTGACTTTTGGTGAAGGTGAAAATCAAGCGAGACAAACCGTTTCTTTTGCGGAAAATAGTGCGGATTATTGGCTA
AAAACTGAAAATGGCAAGCAATACTTAATGGTAAAAGATGAAGTAATTTTGCCTTGTGAAGAAGTAACATTAGTCGGTCG
CCATAATTATATGAACATTTTGGCAGCAACAGCATTGGCACAAGCTGTCGGTATTAATTTAGATTCAATTCGTACCGCAC
TTCGTCATTTCAAAGGGTTAGATCATCGTTTTCAATTAGTGCATCAAGCTAATGGTATTCGTTGGATTAATGACTCTAAA
GCAACAAATGTGGGGAGTACAGTTGCTGCATTAGCTGGGCTTTATATTGAGGGTAAATTGCATTTGTTGCTAGGCGGAGA
CGGAAAAGGGGCTGATTTTTCAGAATTAGCTGAATTAATTAATCAACCACACATTATTTGTTATTGTTTTGGTCGAGATG
GTGTGCAGCTTGCAAAATTTTCATCACAAAGCTATTTGTTTGAAACAATGGAACAAGCGATAGAATTTTTACGCCCAACA
TTGCAAAGCGGAGATATGGTATTATTGTCGCCTGCTTGTGCAAGTCTCGATCAGTTTGCTTCTTTTGAAAAGCGCGGCGA
AGAATTTACGCATTTAGCGCAATATTCAGCCTAA

Protein sequence :
MNAYQNKNITIIGLGKTGLSCVDYLLSQQANIRVIDTRKKPTGIDKLPQNIPLHTGSLNQEWLLESDMIVISPGLAVKTP
EIQTALKAGVEVIGDIELFCRAATKPIVGITGSNGKSTVTTLVYEMAKAAGVKVGMGGNIGIPALSLLNEDCELYVLELS
SFQLETTYSLKAAAATVLNVTEDHMDRYMDLEDYRQAKLRIYHNAEVGVLNNEDKLTFGEGENQARQTVSFAENSADYWL
KTENGKQYLMVKDEVILPCEEVTLVGRHNYMNILAATALAQAVGINLDSIRTALRHFKGLDHRFQLVHQANGIRWINDSK
ATNVGSTVAALAGLYIEGKLHLLLGGDGKGADFSELAELINQPHIICYCFGRDGVQLAKFSSQSYLFETMEQAIEFLRPT
LQSGDMVLLSPACASLDQFASFEKRGEEFTHLAQYSA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00311 YP_008207776.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR25 Protein 1e-54 41
BJAB0868_00315 YP_008211641.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR26 Protein 1e-54 41