Gene Information

Name : tktA (NTHI1189)
Accession : YP_248708.1
Strain : Haemophilus influenzae 86-028NP
Genome accession: NC_007146
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 1136210 - 1138207 bp
Length : 1998 bp
Strand : -
Note : TK; catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during

DNA sequence :
ATGGCAACTCGTAGACAATTAGCCAATGCAATTCGTGTCTTAGCAATGGATTCTGTACAAAAAGCGAAATCTGGTCACCC
TGGTGCACCAATGGGGATGGCGGATATTGCTGAAGTATTATGGCGCGACTTTTTAAAACACAATCCAACCAATCCTAAAT
GGGCTGATCGTGACCGTTTTGTGCTTTCAAATGGACACGGTTCTATGTTGATTTATAGTCTTTTACATTTAACTGGCTAT
GATCTTTCTATCGAAGATTTAAAACAATTCCGTCAATTACATTCTAAAACCCCAGGTCACCCAGAATATGGTTATGCACC
TGGTGTTGAAACCACGACTGGCCCGTTAGGTCAAGGTATCACTAATGCGGTGGGTATGGCAATTGCTGAGAAAACCTTAG
CTGGACAATTTAACCGTGAAGGCCATGAAATTGTCGATCACCACACTTATGTGTTCTTAGGCGATGGCTGTTTAATGGAA
GGGATTTCTCACGAGGCTTGCTCTTTAGCAGGAACATTAGGTCTGGGTAAACTAATCGCATTCTACGATGACAACAATAT
TTCCATTGATGGTCATGTTGATGGCTGGTTCAGTGATGACACCGCCGAGCGTTTTGAAGCTTATGGCTGGCAAGTAATCC
GTAATGTAAATGGTCACAATGCAGAGCAAATTCGCGCTGCTGCCGTTCTTGCTCAAGCAGAAAAAGAAAAACCAACGTTA
ATTATTTGTAAAACCATCATTGGTTTTGGTTCTCCAAATAAATCAGGTTCTCATGATTGCCACGGTGCGCCATTAGGCGA
TGAAGAAATCGCTTTAACCCGCAAAGCACTTGGTTGGGAATATGCGCCATTTGAAATTCCAGCTGAATACTATGCTGAAT
GGTCGGCAAAAGAGAAAGGTGCTGCAGCAGAAAAATCTTGGGAAGAAAAATTTGCCGCTTATGCAAAAGCCTATCCTGAA
TTGGCAGCAGAATTTAAACGTCGTGTTTCTGGCGAATTACCAACAAACTGGGCGGCAGAATCTAAAGCGTTCATCGAAAA
ATTACAAGCAAATCCAGCGAGTATTGCAAGCCGTAAAGCATCACAAAATGCCATTGAAGCCTATGCACACCTATTGCCAG
AATTTTTAGGTGGTTCTGCAGACTTAGCAAGCTCCAACTTAACCTTATGGAGTGGTTCAAAACCGATTCGTGCCCACGAA
AACGTAAGTGGTAACTACATTAACTACGGTGTTCGTGAATTTGGTATGTCTGCCATTATGAACGGCATTGCCTTACACGG
CGGTTTCATTCCTTACGGCGCAACCTTCTTAATGTTCTACGAGTATGCTCACAACGCAGTACGTATGGCAGCATTAATGA
AACAACGCACATTATTCGTTTATACCCACGATTCCATCGGTTTAGGCGAAGATGGACCTACACACCAACCAGTAGAACAA
ACGGCTTCACTACGCTTAATTCCAAACCTTGAAACATGGCGTCCATGTGACCAAGTTGAATCAGCCATCGCATGGCAACA
AGCGGTTGAACGTCAAGATGGCCCAAGTGCGTTAATTTTCACTCGTCAAAATCTTGCTCAAATGAACCGCACTTCTGCAC
AATTAGATGCGGTTAAACGTGGTGCTTATGTATTAAAAGACTGTGATGGCACACCTGAGTTAATTTTCATTGCGACAGGT
TCTGAAGTGGAATTAGCAGTGCAAGCAGCCGAAGCATTAAGTGCTGAAGGTAAAAAAGTACGCGTTGTTTCTATGCCAAG
TACTAACCGTTTCGATAAACAAGACGAAGCATACCGTGAAAGTGTATTACCTGCAGCGGTAACCAAACGTGTTGCGATTG
AAGCGGGTATTGCTGACTTCTGGTATAAATACGTTGGATTCAATGGTCGTGTTGTCGGTATGAATAGCTTTGGCGAATCC
GCACCAGCAGATCAATTATTTAAACTCTTTGGTTTCACTGTTGAAAACGTGGTAGCAAAAGCGAAAGAAATTCTTTAA

Protein sequence :
MATRRQLANAIRVLAMDSVQKAKSGHPGAPMGMADIAEVLWRDFLKHNPTNPKWADRDRFVLSNGHGSMLIYSLLHLTGY
DLSIEDLKQFRQLHSKTPGHPEYGYAPGVETTTGPLGQGITNAVGMAIAEKTLAGQFNREGHEIVDHHTYVFLGDGCLME
GISHEACSLAGTLGLGKLIAFYDDNNISIDGHVDGWFSDDTAERFEAYGWQVIRNVNGHNAEQIRAAAVLAQAEKEKPTL
IICKTIIGFGSPNKSGSHDCHGAPLGDEEIALTRKALGWEYAPFEIPAEYYAEWSAKEKGAAAEKSWEEKFAAYAKAYPE
LAAEFKRRVSGELPTNWAAESKAFIEKLQANPASIASRKASQNAIEAYAHLLPEFLGGSADLASSNLTLWSGSKPIRAHE
NVSGNYINYGVREFGMSAIMNGIALHGGFIPYGATFLMFYEYAHNAVRMAALMKQRTLFVYTHDSIGLGEDGPTHQPVEQ
TASLRLIPNLETWRPCDQVESAIAWQQAVERQDGPSALIFTRQNLAQMNRTSAQLDAVKRGAYVLKDCDGTPELIFIATG
SEVELAVQAAEALSAEGKKVRVVSMPSTNRFDKQDEAYRESVLPAAVTKRVAIEAGIADFWYKYVGFNGRVVGMNSFGES
APADQLFKLFGFTVENVVAKAKEIL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 0.0 77
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 0.0 68