Gene Information

Name : lspA (NTHI1181)
Accession : YP_248701.1
Strain : Haemophilus influenzae 86-028NP
Genome accession: NC_007146
Putative virulence/resistance : Unknown
Product : lipoprotein signal peptidase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0597
EC number : 3.4.23.36
Position : 1129502 - 1130017 bp
Length : 516 bp
Strand : +
Note : prolipoprotein signal peptidase; signal peptidase II; SPase II; lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis

DNA sequence :
ATGTCCAAAAAATCAGGGCTTTCATTTTTATGGTTAAGTGCGGTCGCTTTCGTGGTTGATTTGCTTACAAAATACATTGT
GGTACAAAAATTTGATTTGTATGAAAGTGTTAATGTGCTGCCTGTTTTTAACCTGACTTATGTTCGAAATTATGGCGCAG
CATTTAGTTTCTTAGCGGATCATAGTGGTTGGCAACAATATTTCTTTATTTTGTTGGCATTGGCTATTTCAGGAATGTTG
GTCTATTTTTTAGCAAAAAATAATGCCGAACAAAAAATCCAAAATTCTGCTTATGCACTGATTATTGGTGGGGCGTTAGC
GAATATGGTAGATCGCACTTACAATGGTTTCGTCGTGGATTTCTTTGATTTCTATTGGGATATTTACCATTATCCAGTAT
TTAATATCGCCGATATTGCCATTTGTATTGGCGCAGGGTTATTAGCATTAGATGCGTTTAAGAGCGAAAAGAAAAAAGTA
CAAGATAAACAAGTAGAAAAGTGCGGTCAAAAATGA

Protein sequence :
MSKKSGLSFLWLSAVAFVVDLLTKYIVVQKFDLYESVNVLPVFNLTYVRNYGAAFSFLADHSGWQQYFFILLALAISGML
VYFLAKNNAEQKIQNSAYALIIGGALANMVDRTYNGFVVDFFDFYWDIYHYPVFNIADIAICIGAGLLALDAFKSEKKKV
QDKQVEKCGQK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lspA CAJ77096.1 Lipoprotein signal poeptidase Not tested AbaR1 Protein 1e-20 48
lspA ADZ05771.1 lipoprotein signal peptidase Not tested AbaR11 Protein 1e-20 48
lspA AGK36655.1 lipoprotein signal peptidase Not tested AbaR26 Protein 1e-20 48
ACICU_00236 YP_001844895.1 lipoprotein signal peptidase Not tested AbaR20 Protein 1e-20 48
lspA ACN81031.1 lipoprotein signal peptidase Not tested AbaR5 Protein 1e-20 48
lspA ADI24143.1 lipoprotein signal peptidase Not tested AbaR1 Protein 2e-20 47
lspA CAJ77023.1 lipoprotein signal peptidase Not tested AbaR1 Protein 3e-20 47
lspA ACS32043.1 lipoprotein signal peptidase Not tested AbaR5 Protein 4e-20 47
lspA AAN62189.1 putative lipoprotein signal peptidase LspA Not tested PAGI-2(C) Protein 3e-16 43