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Name : leuS (NTHI1090) Accession : YP_248619.1 Strain : Haemophilus influenzae 86-028NP Genome accession: NC_007146 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0495 EC number : 6.1.1.4 Position : 1036447 - 1039032 bp Length : 2586 bp Strand : + Note : leucine--tRNA ligase; LeuRS; leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRN DNA sequence : ATGCAAGAACAATATCGCCCCGATATGATCGAACCAAAGGTTCAACAATATTGGGCAGAAAATAAAGTTTTCAAAGCAAT CAAAGACGAATCTAAAGAAAAATATTACTGTCTTTCTATGTTCCCATATCCTTCTGGTCGCCTGCATATGGGGCACGTGC GTAACTACACTATTGGTGATGTCATTTCTCGTTATCAACGCATGCTAGGCAAAAACGTATTGCAACCATTTGGTTGGGAT GCTTTCGGCTTACCTGCGGAAGGGGCAGCAATTAAAAATAAAACCGCACCAGCAAAATGGACTTACGAAAATATCGCCTA CATGAAGAAACAACTTCAACTTTTAGGCTTTGGTTTTGACTGGGATCGTGAAATCGCAACCTGTAAACCAGAATACTACA AATGGGAACAATGGTTCTTCACTGAGCTTTACAAAAAAGGCTTAGTGTACAAAAAAACCTCAACCGTAAACTGGTGTCCG AATGATGAAACAGTACTCGCAAACGAGCAAGTACACGAAGGTTGTTGCTGGCGTTGTGATACACCAGTGGAACAAAAAGA AATCCCACAATGGTTTATCAAAATTACTGACTATGCCGAGCAATTATTAGGTGGTTTAGATGCCCTTCCACAATGGCCTG ACATGGTAAAAACCATGCAACGTAACTGGATTGGTCGCTCTGAAGGGGTAGAAATTACCTTTGATGTTGCAAATACCAAC GAAAAAGTAGCAGTTTACACCACGCGTCCAGATACCTTTTACGGCGTGAGTTATTTAGGCATTGCAGCGGCACATCCATT AGCAAGTTTAGCAGCTCAAAACAATTCCGAATTAGCCGCCTTTATCCAAGAAGCGAAAAACGCCAAAGTGGCAGAAGCTG ATCTTGCGACAATGGAGAAAAAAGGAATGGCAACGGGCTTATTTGCTATTCATCCATTGACGGGCGAAAAATTACCGATT TGGGTCGCTAATTTCGTGTTAATGCACTACGGTACTGGCGCAGTAATGGCAGTTCCTGCTCACGACCAACGTGACTTTGA ATTTGCTCAAAAATACAGTTTACAAATCAAGCAAGTTATTGAACCCATTGCAGATGAAGAAATTGATTTAACTAAACAAG CTTTCGTTGAGCACGGTAAATTAGTGAACTCAGCTGAATTTGATGGTAAAGACTTTGATGGTGCATTCAACGGTATCGCG GATAAATTAGAAAAATTAGGTGTTGGAAAACGTCAAGTTAATTACCGTTTACGTGACTGGGGCGTTTCTCGCCAACGTTA TTGGGGTGCGCCAATTCCGATGCTAACCCTTGAAAATGGCGATGTAGTACCTGCACCAATGGAAGATTTACCTATTATTC TGCCTGAAGATGTGGTAATGGATGGCGTAAAAAACCCAATTAAAGCAGATCCTAACTGGGCAAAAACAACCCTTAACGGC GCACCAGCGTTAAAAGAAACGGATACCTTTGATACCTTTATGGAATCCTCTTGGTATTACGCGCGCTACACTTGTCCACA ATATCAAAATGGCATGCTTGATGCGGAAGAAGCAAACTATTGGTTACCAGTGGATCAATATATCGGTGGTATTGAACACG CAACAATGCACTTACTCTACTTCCGCTTCTTCCACAAATTATTGCGTGATGCAGGATTTGTAACCAGTGACGAACCAGCC GATAAATTATTATGTCAAGGTATGGTGCTTGCAGATGCCTTCTACTACACAAGTCCAACCAATGAGCGTATTTGGGTAAG TCCAACACTGGTGACTCTTGAACGTGATGAAAAAGGCAGAATTATTAAAGCCACCGATCCTGAAGGGCGTGAATTAGTCC ACAGTGGCATGACCAAAATGTCGAAATCCAAAAATAACGGTATTGACCCACAAGAAATGGTAGAAAAATATGGTGCCGAT ACTGTTCGCCTCTTTATGATGTTTGCCTCTCCAGCAGAAATGACCTTGGAATGGCAAGAATCTGGCGTAGAAGGGGCGAA ACGTTTCTTAGGGCGTGTTTGGAATTTGGTATATCAATATCAACAAAATCCAGCAAAAACTAGCCTAGATATCACCGCAC TTTCCGCAGAACAAAAAGTGCTTCGTCGTGAAGTTCATAAAACCATTGCGAAAGTGAGCGATGATATTGGTCGTCGTCAA ACATTTAATACTGCGATTGCTGCAGTGATGGAATTGATGAATAAACTGACTAAGGCATCGCTTGATAGCGAGCAAGATCG TGCAGTTATGGCGGAGGCATTAAGTGCAGTTGTTCGTATGCTTTATCCAATTACGCCACATATCTGTTTTGAATTATGGC AAGCTCTTGGCAATGAAAGTGCTATTGATACTGCAGAATGGGTAAAAGCCGATGAAGCCGCAATGGTAGAAGATGAAAAA CTGATTGTTGTGCAAGTAAATGGCAAGGTTCGTGGCAAAGTTACTGTTGCGGCAGATGCAGATGAAGACACAGTCAAAAC GATTGCTTTTGCGGATGAAAATGTGAAGAAATTTATTGATAATCAACACATTGTCAAAGTGATTTATGTCGTAGGTAAAT TATTAAACGTGGTAGTGAAACCATAA Protein sequence : MQEQYRPDMIEPKVQQYWAENKVFKAIKDESKEKYYCLSMFPYPSGRLHMGHVRNYTIGDVISRYQRMLGKNVLQPFGWD AFGLPAEGAAIKNKTAPAKWTYENIAYMKKQLQLLGFGFDWDREIATCKPEYYKWEQWFFTELYKKGLVYKKTSTVNWCP NDETVLANEQVHEGCCWRCDTPVEQKEIPQWFIKITDYAEQLLGGLDALPQWPDMVKTMQRNWIGRSEGVEITFDVANTN EKVAVYTTRPDTFYGVSYLGIAAAHPLASLAAQNNSELAAFIQEAKNAKVAEADLATMEKKGMATGLFAIHPLTGEKLPI WVANFVLMHYGTGAVMAVPAHDQRDFEFAQKYSLQIKQVIEPIADEEIDLTKQAFVEHGKLVNSAEFDGKDFDGAFNGIA DKLEKLGVGKRQVNYRLRDWGVSRQRYWGAPIPMLTLENGDVVPAPMEDLPIILPEDVVMDGVKNPIKADPNWAKTTLNG APALKETDTFDTFMESSWYYARYTCPQYQNGMLDAEEANYWLPVDQYIGGIEHATMHLLYFRFFHKLLRDAGFVTSDEPA DKLLCQGMVLADAFYYTSPTNERIWVSPTLVTLERDEKGRIIKATDPEGRELVHSGMTKMSKSKNNGIDPQEMVEKYGAD TVRLFMMFASPAEMTLEWQESGVEGAKRFLGRVWNLVYQYQQNPAKTSLDITALSAEQKVLRREVHKTIAKVSDDIGRRQ TFNTAIAAVMELMNKLTKASLDSEQDRAVMAEALSAVVRMLYPITPHICFELWQALGNESAIDTAEWVKADEAAMVEDEK LIVVQVNGKVRGKVTVAADADEDTVKTIAFADENVKKFIDNQHIVKVIYVVGKLLNVVVKP |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 3e-153 | 42 |
