Gene Information

Name : serS (RF_1249)
Accession : YP_247265.1
Strain : Rickettsia felis URRWXCal2
Genome accession: NC_007109
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 1320553 - 1321830 bp
Length : 1278 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGTTAAATATCAAATGGATTAGAGAAAATCAAGAATTATTCGATGAAAAGCTTAGCCAAAGATTTATTGAACCTATGTC
TAGTAAAATTGCTATGCTCGACGGAGAGAAAAGAAAAATTACGTGTTTAATTCAAGAATTTCAGCATGCACGCAAGGTAA
AATCAAAGATTTTAGGTAATATGGCCTCTAAAAGCGGCGAAGAGTTTGAAGGGCTACAAAGAGATGTCAAACATATAAAT
GAGAAGTTGGAAGAACTTGAACAGGATCTAAATAATAATAACGAATTAAATGAACTATTAAATATGCTTCCTAATATTCC
GGACGAAGAAGTACCTTACGGAATGGATGAAAGTATGAATAAATTAGTTCGTACTTACGGAGAGACAAATCCAAATGCTT
TGAATAAACAGCATTTTGAACTAGGTACAAAATTAAATTTAATGGATTTTGAACAAACTGCTAAAATTTCTGGAGCTAGA
TTTGTAACGTTAAAAGGTGATTTAGCAAAGCTAGAACGTGCTTTAATTAACTTTATGATTGATGTCCATACTAAAGAGTT
TGACTTCTTTGAGATATCACCTCCGGTACTAGTTCGAGATAATGCTATGTATAATGCAGGACAACTACCTAAATTTGCCG
AAGAGTCTTTCGCAACAACAAATGGTTATAGACTAATTCCAACCGCAGAAGTATCTTTAGTAAATATAGTTGCCGATACT
ATTATACCAAGAGAAAAATTACCGATGCGTTATGTTGCTTACACCCCGTGCTTTAGATCAGAAGCAGGTAGTAGCGGTAG
AGATACAAGAGGTATGATTAGATTACATCAATTCGGTAAAGTTGAGCTAGTATCTATTACTACCACTGAAGAATCAAAAA
ATGAGCATGAATATATAACTAATGCTTCAGAGACTATTTTACAAAAACTGAATCTTCCTTATCGTGTTATGTTACTTTGC
ACCGGAGATATGGGATTTGCGGCAAAAAAAACCTATGATATAGAAGTATGGCTTCCGGGACAAAAGCAATATCGCGAAAT
TGCTAGCTGTTCTAATTGTGGAGATTTTCAAGCACGTAGAATGAAAGCAAGATATAAGGAATTCGGCAGTAACGAAACTA
CCTTAGTTCATACTTTAAATGCTTCAGGATTACCTATCGGAAGAACTATGGTTGCAATACTTGAAAATTATCAGAATGAA
GATGGATCAATAACTATACCTGATGTCTTGATAAATTACATGGGAGGGTTACAAAAAATCACTACATATAGTGAATAA

Protein sequence :
MLNIKWIRENQELFDEKLSQRFIEPMSSKIAMLDGEKRKITCLIQEFQHARKVKSKILGNMASKSGEEFEGLQRDVKHIN
EKLEELEQDLNNNNELNELLNMLPNIPDEEVPYGMDESMNKLVRTYGETNPNALNKQHFELGTKLNLMDFEQTAKISGAR
FVTLKGDLAKLERALINFMIDVHTKEFDFFEISPPVLVRDNAMYNAGQLPKFAEESFATTNGYRLIPTAEVSLVNIVADT
IIPREKLPMRYVAYTPCFRSEAGSSGRDTRGMIRLHQFGKVELVSITTTEESKNEHEYITNASETILQKLNLPYRVMLLC
TGDMGFAAKKTYDIEVWLPGQKQYREIASCSNCGDFQARRMKARYKEFGSNETTLVHTLNASGLPIGRTMVAILENYQNE
DGSITIPDVLINYMGGLQKITTYSE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 1e-78 46