Gene Information

Name : hemC (RF_0817)
Accession : YP_246833.1
Strain : Rickettsia felis URRWXCal2
Genome accession: NC_007109
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 866335 - 867240 bp
Length : 906 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGACAAATTCTATCAGAATAGGTACAAGAAAAAGTCCGCTTGCTTTAATACAAACTAATTTAGTTATTCAACAAATCAA
ACAATTTTTTCCTGATATTAATTGTGAAATAGTACCCATTATTACTAGCGGTGATTTAATCCAAAATAAACCATTATACG
ATATAGGAGGTAAAGCTTTATTTTTAAAGGAAATAGAGCAAGCTTTACTTGATAAAAAAATTGACTTAGCGGTTCATTCT
TTAAAAGACGTACCTGGTAGAATACCCGAAGAGCTAGTAATAGCTGCTATTTTAGAGCGTGAAGACCCTAGAGACGTGTT
TGTTTGTTTAAATTATAAATCCATAGAAGAGCTACCGCAAAATGCCGTAATAGGTAGCTCGGCAGTACGAAGAAAAGCAT
TTATCCAAAAAATAAGATCGGATTTAAAGGTAACGGTTTTTAGGGGGAATATTGATTCAAGAATAAAAAAGTTAATGACC
GCCGAAGTTGACGCAACGATTTTAGCATATGCAGGGCTGAAAAGGCTCAGGGCGTTTAATCCGGAATATTGCCATTTGAT
AGAGTATTCGCAGATGTTGCCGTGTATAGGGCAGGGAGTCATTGCAGTTGAAATACGACAAGACGATAATGCTATGCTTG
AGATATGTAACCAAATTAATCATCTTCCTACCTTTGAGCTAATAAAGCCAGAAAGAGCTTTTTTAGAATATCTAGACGCT
AATTGTCGTACGCCAATTGCCGCTTACTCTAAATATTTAGATGCGGATAATATACAAACCGATTTCATGCTCGGCAACCT
CGATTGCAGTAAAATAATCTTCCACACCGAAGTCACCGATATAAATACCTCAAAAGAAGCAGGCATAAAAGCCGCTAAGA
TGATGTTAAATCAACTGGATAAATAG

Protein sequence :
MTNSIRIGTRKSPLALIQTNLVIQQIKQFFPDINCEIVPIITSGDLIQNKPLYDIGGKALFLKEIEQALLDKKIDLAVHS
LKDVPGRIPEELVIAAILEREDPRDVFVCLNYKSIEELPQNAVIGSSAVRRKAFIQKIRSDLKVTVFRGNIDSRIKKLMT
AEVDATILAYAGLKRLRAFNPEYCHLIEYSQMLPCIGQGVIAVEIRQDDNAMLEICNQINHLPTFELIKPERAFLEYLDA
NCRTPIAAYSKYLDADNIQTDFMLGNLDCSKIIFHTEVTDINTSKEAGIKAAKMMLNQLDK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 8e-49 42
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 8e-49 42