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Name : leuS (RF_0651) Accession : YP_246667.1 Strain : Rickettsia felis URRWXCal2 Genome accession: NC_007109 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0495 EC number : 6.1.1.4 Position : 698909 - 701416 bp Length : 2508 bp Strand : + Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl DNA sequence : ATGAATCAAATAGAACAAAAATGGCAACAAATTTGGTATGATGAGAAAGCTTTTGAGGTATCAAACGAGAGTAGCAAGCC AAAATATTACGTACTTGAAATGTTGCCTTATCCTTCCGGTAAAATCCATGTAGGTCATGTACGCAACTATTCTATAGGTG ATGTTATTGCAAGGTTTATGACTATGCAAGGTTTTAACGTGCTTCATCCGATGGGCTGGGATGCTTTTGGGCTACCTGCC GAAAATGCCGCAATAAAAAATAATTCTCATCCGAAAGATTGGACTTATTCTAATATCGAGAATATGAAAAAGCAGCTAAA ATCTATGGGCTTTTCTTATGATTGGTCTAGAGAGATAAATAGTTGTGATCCGCAGTATTATAAACATGAGCAGAAATTCT TTTTAGAGCTTTATGAGAGAAATCTTGCTTATCAAAAAGAATCGCTTGTTAACTGGGATCCGGTTGATAATACCGTTCTT GCAAATGAGCAAGTTGTAGACGGGCGTGGTTGGCGTTCAGGTGCAATTGTTGAGAAGCGTTATTTAAAGCAATGGTTCTT AAAAATCACCGATTATGCTGAAGAGTTATTAAATGAAATTCAGAATTTAAAAGAATGGCCTGAAGCCGTTCGCTCTATGC AAGAGAAATGGATAGGTAAATCGATAGGTGCTAACTTTCATTTCAAAATTAAGGATAATGAAGATAATACTATAGAAGTA TTCTCAACCAAACCTGAAACTATTTTCGGCGCTGGTTTTATAGGAATTGCCTTTAATCATCCAATAATAGAGAAATTAAT TTCTAAGACACCTGAAATATTGAGTTTTATAACTAAATGTTCGCATATTACAGGAAGTAGCGAACTAGAAAAGACTGAAA AAGAGGGAGTCTTTACCGGTCTTTATGTCATTCATCCTTTCGATTCAAATATAGTTCTACCGGTTATTATTACGAATTTT GTGTTAATGGATTACGGCACTGGTGCTGTTTTCGGTTGTCCTGCTCATGACGAACGTGACCATGAATTAGCTGTTAAAAT GAATTTGCCTATTAAGCAGGTAATTGAAACGGATATTGATGTACAAAAGACCGCTTATACGGAAGATGGAATTTTGGTTA ACTCAGATTTTCTAAACGGCTTAACTAGTAATGAAGCAAAACAAAAAGTAATCGATGAATTTGAGAAACTAGGCATAGGT AAACGCAGTGTATATTATCGTCTAAAAGATTGGGGAATTTCTCGTCAACGCTTTTGGGGTTGTCCTATTCCTATGATTCA CTGTGAAGCTTGCGGCATAGTTCCCGTACCGTGCAGTGACTTACCCGTTACGTTACCTGATGATGTTAGTTTTGACGGTC ACGGTAATCCGCTTGATCATCATCCTAGTTGGAAACATGTTAATTGTCCGAAATGCGATAAGTCGGCTATTCGTGAAACC GATACTTTTGATACATTTTTCGAGTCATCTTGGTATTTTACGAGATATTGCAATAGCAATGCTACAGAGATGACCGATAA AAAAGCTTGTGATTATTGGCTACCGGTGGATAAATATATAGGCGGTATAGAACATGCAGTAATGCATCTATTATATGCAA GGTTTTTCACAAAAGTAATGAACGAACAGAATTACGTAAGCGTTCGTGAGCCTTTTAAAGGGCTATTTACTCAAGGGATG GTGCTGCATGCTACTTATAAAGATGAACATAATAATTGGTTATATCCTGAAGAAGTAGTTAAAAAAGGTAATGAATTTTT TCATAAAGAAAGCAATAATAGAGTAGTGCAGGGACGCATTGAAAAGATGAGTAAGTCTAAAAAGAATCTCATCGATCTTG TGACGATGCAAGAGCAATATGGGGCTGATGCTATTAGGCTTTTTGTACTGTCCGATAGTCCGCCTGAGAAAGATCTAGAA TGGTCGGCAAGCGGTATTGAAGGCTGCTCACGTTTTATTAATAAGCTTGAGCATATGTTTGAGGCGATAGCTTCTTTAAT AGATGATGTGAATAGTGAAATTAACAAAGAATTAAACAGATTAGTTCATTTTACCATAAAGCACGTTGCCGATGATATAA AGCATTTTGTCCTAAATAGAGCAATAGCACGTATGCGTGAGCTTTCTAATGCTATATCTGCTGAGCTTAATAAAGAAGTG GTTGATGTTAAAACCGTAAGATACGGCTTTAATGTTATAGTTCAGCTGCTAAACCCTTTTATCCCGCATATTACGGAAGA AATTTGGCAAAAGCTTGGGAATAAAGAGCGGTTATATAATTCAGCCTTTCCAGCATTTGATGAATCAATGTTAGAATTAG ATACATATGTTATGGCAGTGCAGGTTAATGGCAAACTCCGTGATACTTATGAGTTTAAAACTTCTGCAAGCGAAGATGAA ATAAAGCAAATTACCGTCAATTTGCCAAAAGTACAAAAATTCTTAGAAGGGAAAGAGCCGAAGAAGATTATTCTCGTGCC TCGTAAAATTGTGAATATTATAGTTTGA Protein sequence : MNQIEQKWQQIWYDEKAFEVSNESSKPKYYVLEMLPYPSGKIHVGHVRNYSIGDVIARFMTMQGFNVLHPMGWDAFGLPA ENAAIKNNSHPKDWTYSNIENMKKQLKSMGFSYDWSREINSCDPQYYKHEQKFFLELYERNLAYQKESLVNWDPVDNTVL ANEQVVDGRGWRSGAIVEKRYLKQWFLKITDYAEELLNEIQNLKEWPEAVRSMQEKWIGKSIGANFHFKIKDNEDNTIEV FSTKPETIFGAGFIGIAFNHPIIEKLISKTPEILSFITKCSHITGSSELEKTEKEGVFTGLYVIHPFDSNIVLPVIITNF VLMDYGTGAVFGCPAHDERDHELAVKMNLPIKQVIETDIDVQKTAYTEDGILVNSDFLNGLTSNEAKQKVIDEFEKLGIG KRSVYYRLKDWGISRQRFWGCPIPMIHCEACGIVPVPCSDLPVTLPDDVSFDGHGNPLDHHPSWKHVNCPKCDKSAIRET DTFDTFFESSWYFTRYCNSNATEMTDKKACDYWLPVDKYIGGIEHAVMHLLYARFFTKVMNEQNYVSVREPFKGLFTQGM VLHATYKDEHNNWLYPEEVVKKGNEFFHKESNNRVVQGRIEKMSKSKKNLIDLVTMQEQYGADAIRLFVLSDSPPEKDLE WSASGIEGCSRFINKLEHMFEAIASLIDDVNSEINKELNRLVHFTIKHVADDIKHFVLNRAIARMRELSNAISAELNKEV VDVKTVRYGFNVIVQLLNPFIPHITEEIWQKLGNKERLYNSAFPAFDESMLELDTYVMAVQVNGKLRDTYEFKTSASEDE IKQITVNLPKVQKFLEGKEPKKIILVPRKIVNIIV |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 1e-153 | 41 |
