Gene Information

Name : leuS (cg3346)
Accession : YP_227268.1
Strain : Corynebacterium glutamicum ATCC 13032
Genome accession: NC_006958
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 3193083 - 3195977 bp
Length : 2895 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGAGATGTCCCGTGTACCTACTACACTGTTTAACCATGACTAACCCGAGCGAAGGCACCACTCCCCTGGCGTTCCGTTA
TACCCCGGAACTCGCCAACAAGATCGAAGGTGAGTGGCAGAATTACTGGACTGACAACGGCACATTCAACGCACCCAACC
CAGTGGGTGATTTAGCGCCTGCGGACGGTAAAGCACTTCCTGAGGACAAGCTCTTTGTCCAGGATATGTTCCCGTACCCA
TCCGGAGCTGGCCTGCACGTAGGCCACCCACTCGGTTACATCGCAACGGATGTTTTCGCCCGCTACAACCGCATGCTGGG
CAAGAACGTTCTGCACACCTTGGGCTATGACGCCTTCGGACTGCCAGCAGAGCAGTACGCGATCCAAACCGGTACACACC
CACGCACCACCACCATGGCCAACATTGAGAACATGAAGCGCCAGCTCGGTGCGCTGGGTCTTGGCCATGATTCCCGTCGT
GCGGTGGCCACCACGGATCCTGAGTTCTACAAGTGGACTCAGTGGATCTTCCTGCAGATTTTCAATTCGTGGTTCGATGC
AGAGCAGCAGAAGGCACGTCCCATCAGTGAGCTGATTCCGTTGCTGGAGTCCGGCGAGCTGAAGACTAAGGACGGGGCGG
ATTACAACGCGCTGGGAGACGTCGAAAAGCAAAAAGCGGTGGATGACTACCGCCTTGTTTATCGCTCGAACTCCACCGTG
AACTGGTGCCCAGGCTTGGGCACCGTGTTGGCAAACGAGGAAGTGACCGCGGACGGCCGTTCCGAGCGTGGCAATTTCCC
TGTTTTCCGTAAGAATTTGTCCCAGTGGATGATGCGCATTACCGCGTACTCGGATCGTCTGATCGATGATCTGGAGCTGC
TCGATTGGACTGAGAAGGTCAAGTCCATGCAGCGTAACTGGATTGGCCGTTCCCGCGGCGCTGAAGTTGATTTCAGTGCA
GAGGGCGAAACCGTCACCGTGTTTACCACCCGCCCAGATACTCTGTTCGGCGCGACCTACATGGTTCTTGCACCTGAGCA
TGAGCTGGTCGACGTGCTGCTGGAGAAGGCTGGTTCCTACGAGGGCGTTGATGCCCGTTGGACCAATGGCCAGGCGAGCC
CTGCGGAAGCTGTCGCTGCATACCGCGCCTCCATCGCCGCGAAGTCCGACCTGGAGCGTCAGGAAAACAAGGAAAAGACC
GGCGTCTTCCTGGGCGTTTACGCGACCAACCCAGTCAACGGCGATCAGATCACAGTGTTCATCGCTGACTACGTTCTGAC
CGGCTACGGCACCGGCGCCATCATGGCGGTTCCTGCTCACGACGAGCGCGACTACGAATTCGCCACCGTTTTGGGTCTGC
CTATCAAGGAAGTTGTCGCAGGTGGCAACATCGAAGAGGCTGCTTTCACCGAATCTGGCGAAGCAGTCAACTCTGCGAAC
GACAACGGCCTGGATATCAACGGCCTTGCCAAGGATGAGGCTATTGCCAAGACCATCGAATGGTTGGAAGAAAAGGAACT
TGGCCGCGGCACCATCCAGTACAAGCTGCGCGACTGGCTGTTCGCTCGCCAGCGTTACTGGGGCGAGCCTTTCCCAATCG
TCTACGACGAAAACGGCCAAGCACATGCTCTGCCAGACTCCATGCTTCCAGTCGAGCTGCCAGAGGTAGAGGACTACAAG
CCTGTCTCCTTCGACCCTGAAGACGCAGACTCCGAGCCTTCCCCACCACTGGCTAAGGCCCGCGAATGGGTTGAGGTGGA
ACTCGATCTCGGCGATGGCAAGAAGAAGTACACCCGCGACACCAACGTCATGCCACAGTGGGCAGGTTCCTCCTGGTACC
AGCTGCGCTACGTCGATCCAAGCAACGATGAGCAGTTCTGCAACATCGAAAATGAACGCTACTGGACCGGCCCACGCCCA
GAAACCCACGGACCAAACGATCCAGGCGGCGTAGACCTCTACGTCGGTGGCGTCGAGCACGCAGTTCTCCACCTGCTCTA
CGCACGTTTCTGGCACAAGGTCCTCTTCGACCTGGGCCACGTCTCCTCCAAGGAGCCATACCGTCGCCTGTACAACCAGG
GCTACATCCAGGCCTTCGCCTACACCGATTCCCGTGGCGTCTACGTGCCTGCCGATGATGTCGAAGAGAAGGACGGAAAG
TTCTTCTACCAGGGCGAAGAAGTCAACCAGGAATACGGAAAGATGGGCAAGTCCCTGAAGAACGCCGTTGCCCCAGACGA
TATCTGCAACAACTTCGGTGCTGACACCCTGCGCGTTTACGAGATGGCCATGGGACCTTTGGACACCTCCCGTCCATGGG
CAACCAAGGACGTCGTCGGTGCGCAGCGCTTCCTCCAGCGTCTGTGGCGTCTCGTCGTCGATGAAAACACCGGCGAAGTG
CTCACTCGCGATGAAGTCCTCACCGACGATGACAACAAGCAACTGCACCGCACCATCGCAGGCGTCCGCGACGACTACAC
CAACTTGCGCGTTAACACCGTGGTTGCCAAGCTCATCGAATACGTCAACTACCTGACCAAAACATACCCAGACACCATCC
CAGCTGGCGCAGTCCTGCCACTGATCGTCATGGTCTCCCCTATCGCACCACACATCGCGGAGGAACTCTGGAAGAAGCTC
GGCCACGACGACACCGTCACCTACGAACCATTCCCCACCTTTGAGGAAAAATGGCTCACCGACGATGAAATCGAACTGCC
AGTCCAGGTCAACGGCAAGGTCCGCGGTCGCATCACCGTTGCAGCCGACGCCAGCCAGGAGCAGGTCATCGAGGCAGCGC
TTGCCGACGAGAAGGTGCAGGAGCAAATCTCCGGCAAGAACCTGATCAAGCAGATCGTTGTTCCAGGACGCATGGTTAAC
CTTGTGGTGAAGTAA

Protein sequence :
MRCPVYLLHCLTMTNPSEGTTPLAFRYTPELANKIEGEWQNYWTDNGTFNAPNPVGDLAPADGKALPEDKLFVQDMFPYP
SGAGLHVGHPLGYIATDVFARYNRMLGKNVLHTLGYDAFGLPAEQYAIQTGTHPRTTTMANIENMKRQLGALGLGHDSRR
AVATTDPEFYKWTQWIFLQIFNSWFDAEQQKARPISELIPLLESGELKTKDGADYNALGDVEKQKAVDDYRLVYRSNSTV
NWCPGLGTVLANEEVTADGRSERGNFPVFRKNLSQWMMRITAYSDRLIDDLELLDWTEKVKSMQRNWIGRSRGAEVDFSA
EGETVTVFTTRPDTLFGATYMVLAPEHELVDVLLEKAGSYEGVDARWTNGQASPAEAVAAYRASIAAKSDLERQENKEKT
GVFLGVYATNPVNGDQITVFIADYVLTGYGTGAIMAVPAHDERDYEFATVLGLPIKEVVAGGNIEEAAFTESGEAVNSAN
DNGLDINGLAKDEAIAKTIEWLEEKELGRGTIQYKLRDWLFARQRYWGEPFPIVYDENGQAHALPDSMLPVELPEVEDYK
PVSFDPEDADSEPSPPLAKAREWVEVELDLGDGKKKYTRDTNVMPQWAGSSWYQLRYVDPSNDEQFCNIENERYWTGPRP
ETHGPNDPGGVDLYVGGVEHAVLHLLYARFWHKVLFDLGHVSSKEPYRRLYNQGYIQAFAYTDSRGVYVPADDVEEKDGK
FFYQGEEVNQEYGKMGKSLKNAVAPDDICNNFGADTLRVYEMAMGPLDTSRPWATKDVVGAQRFLQRLWRLVVDENTGEV
LTRDEVLTDDDNKQLHRTIAGVRDDYTNLRVNTVVAKLIEYVNYLTKTYPDTIPAGAVLPLIVMVSPIAPHIAEELWKKL
GHDDTVTYEPFPTFEEKWLTDDEIELPVQVNGKVRGRITVAADASQEQVIEAALADEKVQEQISGKNLIKQIVVPGRMVN
LVVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 7e-158 49