Gene Information

Name : pyk (cg2291)
Accession : YP_226326.1
Strain : Corynebacterium glutamicum ATCC 13032
Genome accession: NC_006958
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 2175696 - 2177129 bp
Length : 1434 bp
Strand : -
Note : catalyzes the formation of phosphoenolpyruvate from pyruvate

DNA sequence :
ATGGGCGTGGATAGACGAACTAAGATTGTATGTACCCTAGGCCCAGCGGTGGCTAGTGCAGATGGAATTCTGCGTTTGGT
AGAAGACGGCATGGATGTTGCTCGCCTCAACTTCTCCCATGGTGACCACCCAGATCATGAGCAAAACTACAAGTGGGTCC
GCGAGGCGGCGGAGAAGACTGGCCGTGCAGTCGGTATTCTCGCAGACCTCCAAGGACCGAAGATCCGTCTTGGCCGTTTC
ACTGACGGCGCAACCGTGTGGGAAAACGGCGAGACCATTCGGATCACCGTTGACGATGTAGAGGGAACGCACGATCGTGT
GTCCACCACCTACAAGAATCTGGCAAAAGACGCGAAGCCAGGCGACCGCCTGCTCGTTGATGACGGCAAGGTTGGCCTCG
TCTGCGTTTCCGTCGAAGGTAACGACGTCATCTGTGAGGTTGTTGAGGGCGGACCAGTCTCCAACAACAAGGGTGTTTCC
CTGCCAGGTATGGATATTTCCGTACCTGCACTGTCCGAAAAGGATATCCGTGACCTGCGCTTCGCCCTGAAGCTCGGCGT
GGACTTTATTGCACTGTCCTTCGTACGTTCCCCAGCAGATGCTGAACTCGTTCACAAGATCATGGACGAAGAAGGTCGTC
GTGTTCCTGTGATCGCCAAGCTGGAAAAGCCAGAGGCTGTCACCTCCCTCGAGCCAATCGTGTTGGCATTCGACGCCGTC
ATGGTTGCTCGTGGTGACCTCGGCGTTGAGGTTCCTCTGGAGGAGGTTCCACTGGTTCAGAAGCGCGCAATCCAGATTGC
CCGTGAGAACGCAAAGCCAGTTATCGTGGCAACCCAGATGCTGGATTCCATGATTGAGAACTCCCGCCCAACCCGTGCGG
AAGCTTCTGACGTGGCAAACGCTGTGCTCGATGGCGCAGATGCTGTCATGCTTTCTGGTGAAACTTCAGTGGGCAAAGAT
CCGCACAACGTTGTGCGCACCATGTCTCGCATTGTTCGCTTCGCTGAAACCGACGGTCGCGTCCCAGACCTGACCCACAT
CCCTCGCACTAAGCGTGGCGTTATTTCCTACTCTGCACGTGATATCGCCGAGCGCCTCAACGCTCGTGCATTGGTTGCGT
TCACCACCTCTGGTGATACCGCAAAGCGTGTGGCTCGTCTGCACAGCCACCTGCCACTGCTCGTGTTCACTCCAAATGAG
GCAGTTCGCTCTGAGCTGGCGCTGACCTGGGGTGCAACCACCTTCCTGTGTCCACCTGTCAGCGATACCGATGACATGAT
GCGCGAAGTCGACCGTGCTCTTTTAGCAATGCCTGAGTACAACAAGGGTGACATGATGGTTGTTGTTGCAGGTTCCCCTC
CTGGTGTTACCGGTAACACCAACATGATTCACGTCCACCTTCTTGGTGACGACACAAGGATTGCAAAGCTCTAA

Protein sequence :
MGVDRRTKIVCTLGPAVASADGILRLVEDGMDVARLNFSHGDHPDHEQNYKWVREAAEKTGRAVGILADLQGPKIRLGRF
TDGATVWENGETIRITVDDVEGTHDRVSTTYKNLAKDAKPGDRLLVDDGKVGLVCVSVEGNDVICEVVEGGPVSNNKGVS
LPGMDISVPALSEKDIRDLRFALKLGVDFIALSFVRSPADAELVHKIMDEEGRRVPVIAKLEKPEAVTSLEPIVLAFDAV
MVARGDLGVEVPLEEVPLVQKRAIQIARENAKPVIVATQMLDSMIENSRPTRAEASDVANAVLDGADAVMLSGETSVGKD
PHNVVRTMSRIVRFAETDGRVPDLTHIPRTKRGVISYSARDIAERLNARALVAFTTSGDTAKRVARLHSHLPLLVFTPNE
AVRSELALTWGATTFLCPPVSDTDDMMREVDRALLAMPEYNKGDMMVVVAGSPPGVTGNTNMIHVHLLGDDTRIAKL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 7e-69 42
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 8e-69 42
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 7e-69 42
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 3e-68 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk YP_226326.1 pyruvate kinase VFG0479 Protein 3e-69 42