Gene Information

Name : BruAb2_0066 (BruAb2_0066)
Accession : YP_222878.1
Strain :
Genome accession: NC_006933
Putative virulence/resistance : Virulence
Product : type IV secretion system protein VirB4
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG3451
EC number : -
Position : 62703 - 65198 bp
Length : 2496 bp
Strand : -
Note : similar to BRA0066, type IV secretion system protein VirB4

DNA sequence :
ATGGGCGCTCAATCCAAATACGCGCAACAGCTCAATAATGAACGGTCACTTGCACCGTTCATTCCCTTCAGGAGCCAGGT
TGGCCCGACCACCGTGATAACGCGTGACGGTGATTTCGTGCGCACATGGCGCATCGCGGGCCTGGCTTTCGAGACGCAGG
ACAAGGAGAAACTGTTGATCCGCAAGGACCAGCTTAACACCTTGTTCCGTGCCATCGCCTCAAACAATGTGGCGCTGTGG
TCCCACAACGTACGGCGCAGAACCTGGGATCACTTGAAATCCTTCTTTTCCAATCCGTTCTGCGACGCTCTCGACAAGAA
GTATTACGGATCGTTTTCCGGCTACCGAATGATGTCAAACGAACTGTATCTGACGGTTATTTACCGGCCAGTGCCGGCGA
AGATCAGCAGGTTGTTCAACGTGGCCGTTCATCGTTCGCATGCGGAAATCTTACAGGAGCAGCAGCTTGCCATCCGCAAG
CTGGACGAAATCGGCAATCAAATTGAAACCAGCTTGCGTCGCTACGGTGGCGATGACGGGCGTGGCATCGAAGTGCTGAG
CACCTATGAGGACAAACACGGCGCACTGTGCTCACAGCAGCTTGAATTTTATAACTTCCTTCTCTCAGGCGAATGGCAGA
AGGTGCGCGTGCCATCCTGCCCACTGGATGAATATCTGGGCACCGGGTGGGTGTATGCTGGCACTGAAACCATCGAGATA
CGCACCGCGAACGCGACGCGCTATGCGCGTGGCATCGATTTCAAGGACTATGCGAACCACACCGAGCCGGGCATTTTGAA
CGGCCTGATGTATAGCGATTACGAGTACGTCATCACACAATCCTTCAGCTTCATGACAAAGCGGGATGGCAAGGAGTTCC
TGACACGGCAAAAGCAGCGGCTCCAAAATACCGAAGACGGCAGCGCATCCCAGATCATGGAAATGGACATTGCCATCGAC
CAGCTCGGCCGGGGCGATTTCGTCATGGGTGAATATCATTATTCGCTGCTGGTATTTGCCGAAGACATGGAGACGGTGCG
CCACAACACATCACATGCGATGAACATCCTGCAAGACAATGGTTTTCTGGCGACGGTGATCGCCACGGCCACGGATGCGG
CGTTCTATGCACAACTGCCATGTAACTGGCGGTATCGGCCGCGCGTGGCGGGCCTGACCTCGCTCAACTTCGCCGGTCTG
TCATGTTTCCATAATTTCCGCGCAGGCAAGCGGGATGGCAACCCCTGGGGGCAGGCATTGACGCTGCTCAAAACCCCTTC
CGGACAGCCCGCCTACCTGAACTTCCACTATTCAAAAGGCGACGAAGACAACTTCGACAAGAAGCTTCTGGGCAATACCC
GCATCATCGGCCAGTCCGGCGCTGGTAAAACTGTCCTGATGAACTTCTGCCTCGCGCAAGCGCAGAAGTATTTGCACAAT
GCTCCGATGGGTATGTGCAACGTCTTTTTCGACAAGGATCAAGGCGCGAAAGGGACTATTCTTGCCATTGGCGGCAAATA
CCTTGCCATCAGGAACGGCGAACCCACCGGGTTCAACCCATTCCAGATGGAGCCAACAGCGGGGAACATCCTGTTCCTTG
AAAAACTCGTACAGGTACTGGTATCGCGTGATGGCCAGCACGTGACCACAACGGACGAAAGCCGGATCAGTCATGCCATA
CGTACGGTCATGCGCATGCGCCCGGAGCTGCGGCGTCTGTCGACGGTGCTGCAAAACGTTACCGAAGGCAGCGACCGCCA
AGATCGTGAAAACAGCGTGGCGAAGCGGCTCGCGAAGTGGTGTTTTGATGACGGCACCGGCAAGCGGGGCACATTCTGGT
GGGTGCTGGATTGCCCGCAAGACCAGATCGACTTCAACACGCATAGCAATTACGGTTTCGATGGCACCGACTTCCTCGAC
AACGCCGACGTGCGTACGCCGATTTCCATGTACCTGCTGCATCGTATGGAATTGGCTATCGACGGGCGTCGTTTCATCTA
CTGGATGGACGAGGCGTGGAAGTGGGTAGACGACGAAGCATTCAGCGAGTTCGCCAATAACAAGCAGCTTACCATCCGCA
AGCAAAACGGCCTGGGCGTGTTTGCCACGCAAATGCCCTCCAGCCTGCTCAACTCCAAAGTCGCGTCGGCCCTGGTGCAA
CAGGTGGCGACGGAAATCTATCTGCCGAATCCGAAAGCCGATTATCACGAGTACACGGACGGCTTCAAGGTGACGAACGA
GGAGTTCGACATCATCCGCAGTATGAGCGAGGAAAGCCGCATGTTCCTGGTCAAGCAGGGGCATCATTCGATGATTTGCC
GCCTGGAGCTTAATGGCTTTGATGACGAACTGGCGATCCTCTCAGGCAGCTCGGACAACAACGAGTTGCTGGACCAGGTC
ATTGCCGAAGTCGGGGACGACCCTTCGGTATGGCTTCCGGTGTTCCAGGAGCGCCGGAAAGCACGCATTGCGTCGTCCAA
ATCAACAGGAAGGTGA

Protein sequence :
MGAQSKYAQQLNNERSLAPFIPFRSQVGPTTVITRDGDFVRTWRIAGLAFETQDKEKLLIRKDQLNTLFRAIASNNVALW
SHNVRRRTWDHLKSFFSNPFCDALDKKYYGSFSGYRMMSNELYLTVIYRPVPAKISRLFNVAVHRSHAEILQEQQLAIRK
LDEIGNQIETSLRRYGGDDGRGIEVLSTYEDKHGALCSQQLEFYNFLLSGEWQKVRVPSCPLDEYLGTGWVYAGTETIEI
RTANATRYARGIDFKDYANHTEPGILNGLMYSDYEYVITQSFSFMTKRDGKEFLTRQKQRLQNTEDGSASQIMEMDIAID
QLGRGDFVMGEYHYSLLVFAEDMETVRHNTSHAMNILQDNGFLATVIATATDAAFYAQLPCNWRYRPRVAGLTSLNFAGL
SCFHNFRAGKRDGNPWGQALTLLKTPSGQPAYLNFHYSKGDEDNFDKKLLGNTRIIGQSGAGKTVLMNFCLAQAQKYLHN
APMGMCNVFFDKDQGAKGTILAIGGKYLAIRNGEPTGFNPFQMEPTAGNILFLEKLVQVLVSRDGQHVTTTDESRISHAI
RTVMRMRPELRRLSTVLQNVTEGSDRQDRENSVAKRLAKWCFDDGTGKRGTFWWVLDCPQDQIDFNTHSNYGFDGTDFLD
NADVRTPISMYLLHRMELAIDGRRFIYWMDEAWKWVDDEAFSEFANNKQLTIRKQNGLGVFATQMPSSLLNSKVASALVQ
QVATEIYLPNPKADYHEYTDGFKVTNEEFDIIRSMSEESRMFLVKQGHHSMICRLELNGFDDELAILSGSSDNNELLDQV
IAEVGDDPSVWLPVFQERRKARIASSKSTGR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
trwK YP_001610476.1 TrwK protein Virulence Not named Protein 1e-159 42
trwK CAD42844.1 TrwK protein Not tested trw-PAI Protein 9e-160 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
BruAb2_0066 YP_222878.1 type IV secretion system protein VirB4 VFG2211 Protein 0.0 99
BruAb2_0066 YP_222878.1 type IV secretion system protein VirB4 VFG0018 Protein 0.0 53
BruAb2_0066 YP_222878.1 type IV secretion system protein VirB4 VFG2259 Protein 1e-160 42