Gene Information

Name : lysS (MMOB0440)
Accession : YP_015741.1
Strain : Mycoplasma mobile 163K
Genome accession: NC_006908
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 61535 - 62998 bp
Length : 1464 bp
Strand : +
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGAACCAAAAATTAAGTGAGCAAGAACTCATTCGACGTCAAAAAATTGAAAAACTACAAAAATTAGGTGTAGAAGTTTT
TCACGAAACAGTGAAATTCGATTTAAATATTAATAAAATTATCCAAAAATATAATTCATTTTCAAAAGATGAATTAGCAA
AAGATGAATTTTCATTATCAACAACAGGAAGAATTATTACAATTAGAAGTTCCTTTTTAGTTTTAAAATCACAAGGAAGT
AAATTCCAAATTTACTTACCAATCAAAGAATTAGACAAAAAATACTTAGAATTAATTGATCTATTAGATATAGGAGATAT
TATTTTTGTTAATGGAAAGTTAATGAAAACTCAAACAGGTGAGTTAACTTTAAGAGCAAATGAATTGAAACTTTTATCAA
AATCTTTAAAAGTTTTACCTGATAAATTTCATGGCCTAAATGATATTGAAGAAAGATACCGTCATCGCTATGTTGATTTA
ATTGTAAATGATGATGTTAGAAAAACATTTTTATTAAGAAGTAGAATTATTTCTTTAATAAGAAAATATTTTGACAACCT
AGAATATTTAGAAGTTGATACTCCTGTTTTACAACCAATTTTAGGTGGTGCAAGTGCAAAGCCATTTATAACAAAATTTA
ATGCTTTAAATAGTAATTTTTATTTAAGAATTGCAACAGAACTACCACTTAAAAAATTAGTTGTAGGTGGATTTGATAGA
GTTTATGAGATTGGAAGAATTTTCAGAAATGAAGGAGTAGACACAACTCATAATCCTGAATTTACCTCAATTGAATATTA
TGAAGCATATTCTAATAATGAAGGAATGATGAATCGAACAGAAGATTTATTTAAATTTATTGCAAAAGAATTAAATTTAA
AAACAATCTTTTTCAATGGATATGAGATAGATTTAAATAAACCATTTAGAAGACTAAATATGGTGGAAGCTTTAAATGAG
AAATTGGGAATTGATTTATATAAAATTTCATTTGAAGATGCAAAAGTCCTTGCAAAAAAACATCATATAAAAGTTGAATC
ATATTTTAAAATTGGACACATTATCAATGAATTATTTGAATTATTTATAGAAAAAGATTTGATTCAACCAACTTTTGTTT
ATGGGCACCCAATTGAAATTAGTCCTTTAGCTAATAAAAACAAAAAAAATCCCAATTTTACAGATCGTGCCGAACTGTTT
ATCGGTACAAAAGAATATGCTAATATGTTTACAGAATTAACTGATCCAATTGATCAACTAGAAAGATTTAAAGATCAGCA
AAATGAAAAGGATAATGGTAACGAAGAGGCAAATGAAATCGATTATGATTTTGTTGAAGCTCTTGAATATGGTTTACCTC
CAACAGGTGGATGTGGAATTGGTATTGATAGATTAGTGATGTTATTCACAAATAATGAATCAATTAGAGAAGTTTTATTA
TTCCCACACTTAAAAAATAAATAA

Protein sequence :
MNQKLSEQELIRRQKIEKLQKLGVEVFHETVKFDLNINKIIQKYNSFSKDELAKDEFSLSTTGRIITIRSSFLVLKSQGS
KFQIYLPIKELDKKYLELIDLLDIGDIIFVNGKLMKTQTGELTLRANELKLLSKSLKVLPDKFHGLNDIEERYRHRYVDL
IVNDDVRKTFLLRSRIISLIRKYFDNLEYLEVDTPVLQPILGGASAKPFITKFNALNSNFYLRIATELPLKKLVVGGFDR
VYEIGRIFRNEGVDTTHNPEFTSIEYYEAYSNNEGMMNRTEDLFKFIAKELNLKTIFFNGYEIDLNKPFRRLNMVEALNE
KLGIDLYKISFEDAKVLAKKHHIKVESYFKIGHIINELFELFIEKDLIQPTFVYGHPIEISPLANKNKKNPNFTDRAELF
IGTKEYANMFTELTDPIDQLERFKDQQNEKDNGNEEANEIDYDFVEALEYGLPPTGGCGIGIDRLVMLFTNNESIREVLL
FPHLKNK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 7e-87 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_015741.1 lysyl-tRNA synthetase VFG1668 Protein 4e-87 47