Gene Information

Name : thyA (MMOB0340)
Accession : YP_015731.1
Strain : Mycoplasma mobile 163K
Genome accession: NC_006908
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 49646 - 50512 bp
Length : 867 bp
Strand : +
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGGAACAATATTTATCTTTACTTAAAGAAATTTTAGAAAAAGGACAAAAAAAAGAAGATCGTACTAATACAGGCACAAT
TTCTTATTTTGGAACTCAAAGAAGATATGATCTATCTAAAGGATTTCCTTTAGTAACAACTAAAAAAGTTCATCTTAAAT
CAATTATTTTTGAACTATTATGATTTATTAAAGGCGATACAAATATTAAGTATCTAGTTGATAATGGAGTAAATATTTGA
AATGAATGGCCTTATGAAACTTTTAAAAAATCAAAAGATTTTAATGGTGAATCTTTAGCTGATTTTGTTTTAAAAATCAA
AAGTGATACTCTTTTTGCTAAAAAATATGGTGAATTAGGTCCTGTTTATGGAAAACAGTGAAGAAATTTTAATGGCACAG
ACCAACTTTTTGATGCAATTGAGACAATTAAAAAAAATCCTGATTCAAGGAGAATTATTGTTTCGGCTTGAGCTGCAAAT
GAAATTTCCAAAATGGCTCTTCCTCCTTGCCATGCTTTTTTTCAATTTTATGTAAATAATAATAAATTATCATTACAGTT
ATATCAAAGATCAGGAGATACATTTTTAGGTGTCCCTTTTAATATTGCTTCTTATTCAATTCTTCTTGCAATGGTTGCTC
AAATAACAAATTATGAAGTAGGTGAATTTATTCACACAATAGGTGATACTCACATTTATCTAAATCATTTAGAACAAGTA
GAAGAGCAATTATCAAGAAAACCTTTAAAATTACCAAAATTAGTTTTGAACAAAAAAATTAAAAATATTGATGATTTTAA
ATATGAAGATATTGAAATTATTGATTATGAATCTCATCCTGCAATTAAAGCAAAGGTGGCTGTATAA

Protein sequence :
MEQYLSLLKEILEKGQKKEDRTNTGTISYFGTQRRYDLSKGFPLVTTKKVHLKSIIFELLWFIKGDTNIKYLVDNGVNIW
NEWPYETFKKSKDFNGESLADFVLKIKSDTLFAKKYGELGPVYGKQWRNFNGTDQLFDAIETIKKNPDSRRIIVSAWAAN
EISKMALPPCHAFFQFYVNNNKLSLQLYQRSGDTFLGVPFNIASYSILLAMVAQITNYEVGEFIHTIGDTHIYLNHLEQV
EEQLSRKPLKLPKLVLNKKIKNIDDFKYEDIEIIDYESHPAIKAKVAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_189147.1 thymidylate synthase Not tested ¥ÕSP¥â Protein 2e-70 54
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 8e-60 53