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Name : hsdM (MMOB2840) Accession : YP_015981.1 Strain : Mycoplasma mobile 163K Genome accession: NC_006908 Putative virulence/resistance : Unknown Product : type I restriction enzyme m protein Function : - COG functional category : V : Defense mechanisms COG ID : COG0286 EC number : 2.1.1.72 Position : 348172 - 349752 bp Length : 1581 bp Strand : + Note : COG0286; expression validated by proteogenomic mapping: 10 unique peptides covering 26.2% of sequence DNA sequence : ATGAATAAAAATAATGAAATTGAAAAAAACACGTTAAATAAAACAATTTGAAAAAATGTAAGTGAATTGAAAAAAAGTAT TTGAAATGCTGATGAATGAGATTTTAAGGAATACGTTTTTGGAATAATATTCTATCGATACATTTCAGAAAATTTAGCTG ATTATATTAATCAAGATGAATGGAAAGCAAATAAAAATACAAATTTTCGTTATGAAAATATTGAGGATAATTATATTTTA TCTAGAAAAGAAGAAATTAAAGAACTTATTAAGGATAAAGGTTTTTTTATAAAACCAAGTCATTTGTTTATAAATATTCT AAAAAAATCTCTAAATGATAAAGATCTTAATGTCACATTAGGAGAAGTATTTGAAGAAATAGAATCATCTACAAATGGAA CAACAAGCGAAAAAAGTTTTAAAGGATTATTTGCTGATATTAATCTTAACAATTCTAAATTAGGTTCTACAGTAAATGAG CGTAATGAAAATTTAGCAAAATTAATTAAAGTTATTGGTGAAATGGAATTGGGAAATTTTCAAGATAATTCAATTGAATC TTTTGGAGATGTTTATGAATATCTTATGAGCATGTATGCTTCTAATGCAGGTAAAAGTGGCGGAGAATATTATACACCAC AAGAAGTTAGTGAATTATTAGCAAAAATTACTTTAGTTGGTAAAAAAGAAATTAATAAAGTTTATGATCCAGCTTGTGGT TCAGGTTCTTTATTATTAAATTTTGCCAAAATTTTAGGAAAAGAAAAAGTAAGGAATGGTTTTTTTGGTCAAGAAACTAA TCAAACAACTTATAATCTTTGTCGTATTAATATGTTTTTACATGATATTAATTACAATAAATTTAATATAAGTCAAGGAG ATACTTTAACAAATCCACTTCATAATAAATTTGAGCCATTTGAAGCTATTGTTTCAAATCCGCCATATTCAATTAAATGA GCAGGTAAAAGTAATCCTTTACTAATAAATGATCCAAGATTTTCTCCGGCCGGAGTTTTAGCTCCTGAATCTAAAGCTGA TTTAGCGTTTATTATGCACTCGCTTTCATATCTTGCAGTTAATGGAACGGCAGCAATTGTTACTTTTCCAGGGGTTATGT ATCGTGGAGGAGCTGAGCAAAAAATTAGAAAATACCTTGTTGACAATAATTTTATTGATGCCATAATTCAATTGCCTGAA AACTTATTTTTTGGAACAAGTATAGCAACTTGTATTTTAGTATTGAAAAAAAATAAATTAGTAAATGATATTCTTTTTAT CGATGCTTCAAAGGAGTTTCAAAAAATAACAAATAGCAATAAATTGTCAAAAGAAAATATTAGTAAAATTTTAAATACAT ATGAAAAAAGAATTGATTTAGAGCATTTCACAAATAAAGTTTCAAACAATAAAATTTCTGAAGAAAATTACAACTTATCA GTTTCCACTTATATAGGTCAAAAATCTGAAAAAGAAATAATTGATATTAATCTTCTTAATGAAGAAATAAAAACAATTGT AACTAAAGGAAAAGTTTTGAGAGAAGAAATAGATAAAATTATTAAGGAAATTGAAAATTAA Protein sequence : MNKNNEIEKNTLNKTIWKNVSELKKSIWNADEWDFKEYVFGIIFYRYISENLADYINQDEWKANKNTNFRYENIEDNYIL SRKEEIKELIKDKGFFIKPSHLFINILKKSLNDKDLNVTLGEVFEEIESSTNGTTSEKSFKGLFADINLNNSKLGSTVNE RNENLAKLIKVIGEMELGNFQDNSIESFGDVYEYLMSMYASNAGKSGGEYYTPQEVSELLAKITLVGKKEINKVYDPACG SGSLLLNFAKILGKEKVRNGFFGQETNQTTYNLCRINMFLHDINYNKFNISQGDTLTNPLHNKFEPFEAIVSNPPYSIKW AGKSNPLLINDPRFSPAGVLAPESKADLAFIMHSLSYLAVNGTAAIVTFPGVMYRGGAEQKIRKYLVDNNFIDAIIQLPE NLFFGTSIATCILVLKKNKLVNDILFIDASKEFQKITNSNKLSKENISKILNTYEKRIDLEHFTNKVSNNKISEENYNLS VSTYIGQKSEKEIIDINLLNEEIKTIVTKGKVLREEIDKIIKEIEN |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| SSP0053 | YP_300143.1 | type I restriction-modification system methyltransferase subunit | Not tested | SCC15305cap | Protein | 1e-91 | 42 |
| hsdM | NP_646568.1 | hypothetical protein | Not tested | vSa¥â | Protein | 2e-92 | 41 |
| hsdM | YP_001331432.1 | type I restriction-modification system, methyltransferase subunit | Not tested | vSa¥á | Protein | 3e-92 | 41 |
| SAMSHR1132_03780 | YP_005324900.1 | putative type I restriction enzyme modification protein | Not tested | vSa¥á | Protein | 1e-91 | 41 |
| SAV1808 | NP_372332.1 | type I restriction enzyme EcoR124II M protein | Not tested | vSa¥â | Protein | 2e-92 | 41 |
| hsdM | YP_493119.1 | type I restriction-modification system, M subunit | Not tested | vSa¥á | Protein | 3e-92 | 41 |
| SA1626 | NP_374915.1 | hypothetical protein | Not tested | vSa¥â | Protein | 2e-92 | 41 |
| SAR0433 | YP_039884.1 | type I restriction enzyme modification protein | Not tested | vSa¥á | Protein | 7e-92 | 41 |
| hsdM | NP_373642.1 | type I site-specific deoxyribonuclease LldI subunit HsdM | Not tested | vSa¥á | Protein | 6e-92 | 41 |
| hsdM | NP_645209.1 | type I site-specific deoxyribonuclease LldI chain hsdM | Not tested | vSa¥á | Protein | 6e-92 | 41 |
| SAS0394 | YP_042520.1 | restriction enzyme modification protein | Not tested | vSa¥á | Protein | 5e-92 | 41 |
| SAMSHR1132_16570 | YP_005326167.1 | restriction-modification system, M subunit | Not tested | vSa¥â | Protein | 2e-92 | 41 |
| hsdM2 | YP_186690.1 | type I restriction-modification system, M subunit | Not tested | vSa¥â | Protein | 3e-92 | 41 |
| SAS1732 | YP_043848.1 | type I restriction enzyme modification protein | Not tested | vSa¥â | Protein | 2e-92 | 41 |
| hsdM1 | YP_185366.1 | type I restriction-modification system, M subunit | Not tested | vSa¥á | Protein | 3e-92 | 41 |
| SAKOR_00415 | YP_008490599.1 | Type I restriction-modification system methylation subunit | Not tested | vSa¥á | Protein | 2e-92 | 41 |
| hsdM | YP_001332734.1 | type I restriction-modification system, methyltransferase subunit | Not tested | vSa¥â | Protein | 2e-92 | 41 |
| hsdM | YP_494443.1 | type I restriction-modification system, M subunit | Not tested | vSa¥â | Protein | 2e-92 | 41 |
| SAKOR_01757 | YP_008491945.1 | Type I restriction-modification system methylation subunit | Not tested | vSa¥â | Protein | 2e-92 | 41 |
