Gene Information

Name : leuS (SC0678)
Accession : YP_215665.1
Strain : Salmonella enterica SC-B67
Genome accession: NC_006905
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 751672 - 754347 bp
Length : 2676 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
TTGACGTGCGTGTTTGGGCTATGCTATGCGGATCTAAACACCACCTCTAAAGCTACATTTGTAGCTGTATCGAAAACAGG
ACTACTGGCTGCCATGCAAGAGCAATACCGCCCGGAAGAGATAGAATCCAAAGTACAGCTTCACTGGGATGAGAAGCGCA
CATTTGAAGTGACCGAAGACGAGAGCAAAGAGAAGTATTACTGCCTGTCGATGCTTCCCTATCCTTCTGGCCGACTACAC
ATGGGCCACGTACGTAACTACACCATCGGCGACGTGGTTGCCCGCTACCAGCGTATGCTGGGCAAAAACGTGCTGCAGCC
AATCGGCTGGGACGCCTTCGGCCTGCCGGCGGAAGGCGCGGCGGTGAAGAACAACACCGCGCCGGCACCGTGGACGTACG
ACAACATCGCGTATATGAAAAACCAGCTCAAAACGCTGGGTTTTGGCTATGACTGGAGCCGTGAAATCGCGACCTGCACC
CCGGAATACTACCGTTGGGAACAGAAGTTCTTCACCGAGCTGTATAAAAAAGGCCTGGTGTACAAGAAGACTTCTGCCGT
TAACTGGTGCCCGAACGATCAGACCGTTCTCGCCAACGAACAGGTGATCGACGGCTGCTGCTGGCGCTGCGACACCAAAG
TTGAGCGTAAAGAGATCCCACAGTGGTTTATCAAAATCACCGCTTACGCAGACGAGCTGTTGCGCGATCTGGATAAGCTG
GACCACTGGCCTGATACCGTAAAAACGATGCAGCGCAACTGGATTGGCCGCTCTGAAGGCGTGGAAATCACCTTCGATGT
GAAGGGTTACGATAACACCCTGACCGTCTATACCACCCGTCCGGATACCTTTATGGGCGCCACTTACCTGGCGGTGGCCG
CCGGTCATCCGCTGGCGCAAAAAGCGGCGGCGAACAACGCCGAGCTGGCGGCGTTCATCGACGAATGCCGTAACACCAAA
GTGGCCGAAGCCGAAATGGCGACCATGGAGAAAAAAGGCGTCGACACCGGCTATAAAGCGATTCATCCGTTAACTGGCGA
AGAGATCCCGGTCTGGGCGGCAAACTTTGTCCTGATGGAGTACGGCACTGGCGCGGTGATGGCCGTTCCGGGTCACGATC
AGCGCGACTACGAATTTGCCTCCAAATATGGTTTGACCATCAAGCCGGTAATTCTGGCCGCTGACAGTTCCGAGCCGGAT
CTTTCCGAACAGGCGCTGACCGAAAAAGGCGTGCTGTTTAACTCCGGCGAGTTCGACGGTCTGGCCTTTGAAGCGGCGTT
TAACGCCATTGCCGATAAACTGGCGGAAAAAGGCGTCGGCGAACGTAAAGTGAACTATCGTCTGCGTGACTGGGGCGTTT
CCCGTCAGCGTTACTGGGGCGCGCCGATCCCGATGGTCACCCTGGAAGACGGCACCGTGCTGCCGACGCCGGAAGATCAA
CTGCCGGTTATTTTGCCGGAAGACGTCGTCATGGACGGCATCACCAGCCCGATCAAGGCCGATCCTGAGTGGGCGAAAAC
CACCGTTAACGGTATGCCGGCGCTGCGTGAAACCGACACCTTCGACACCTTTATGGAATCGTCATGGTACTACGCGCGTT
ACACCTGCCCGCAGTATCAGGAAGGAATGCTGGATTCGAAAGCGGCAAACTACTGGCTGCCGGTCGACATCTACATCGGC
GGTATTGAACATGCCATCATGCACCTGCTCTACTTCCGCTTCTTCCATAAGCTGATGCGCGATGCGGGCATGGTCACCTC
TGACGAGCCGGCTAAACAGTTGCTGTGCCAGGGCATGGTACTGGCGGATGCGTTCTATTATGTCGGCGAGAACGGCGAAC
GTAACTGGGTTTCGCCAGTTGACGCTATCGTCGAGCGCGATGAAAAAGGCCGCATTGTCAAAGCAAAAGACGCAGCGGGT
CATGAGCTGGTCTACACTGGCATGAGTAAAATGTCCAAGTCGAAAAATAACGGTATCGACCCGCAGGTAATGGTTGAACG
TTATGGCGCGGACACGGTACGCCTGTTTATGATGTTCGCTTCTCCGGCGGATATGACTCTGGAATGGCAGGAGTCCGGCG
TAGAAGGCGCAAACCGCTTTATTAAACGCGTCTGGAAGCTGGTTTACGAACACACCGCTAAAGGTCCTGTCGCGGCGCTG
AACGTCGATGCGCTGAGCGAAGATCAAAAAGCGCTGCGTCGCGATGTGCATAAAACCATTGCCAAAGTGACCGATGATAT
CGGCCGCCGTCAGACCTTCAACACCGCCATTGCGGCGATCATGGAGTTGATGAACAAACTGGCGAAAGCCCCGCAGGAAG
GCGAACAAGACCGCGCACTGCTTCAGGAAGCGCTGCAGGCCGTCGTGCGTATGCTTAATCCGTTCACCCCGCACGTCTGC
TTTACCTTGTGGCAGGAACTGGGTGGCGAAGGCGATATCGACAACGCGCCGTGGCCGGTTGCCGACGAGCAGGCAATGGT
GGAAAACACCACGCTGGTTGTCGTGCAGGTTAACGGTAAAGTTCGCGGTAAGATCACCGTTGCGGTGGATGCCACCGAAG
AACAGGTGCGTGAACGTGCAGGCCAGGAACATCTGGTGGCAAAATATCTTGATGGCGTTACCGTGCGTAAAGTGATTTAC
GTTCCAGGTAAACTCCTCAATCTGGTTGTTGGCTAA

Protein sequence :
MTCVFGLCYADLNTTSKATFVAVSKTGLLAAMQEQYRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGRLH
MGHVRNYTIGDVVARYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKTLGFGYDWSREIATCT
PEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVIDGCCWRCDTKVERKEIPQWFIKITAYADELLRDLDKL
DHWPDTVKTMQRNWIGRSEGVEITFDVKGYDNTLTVYTTRPDTFMGATYLAVAAGHPLAQKAAANNAELAAFIDECRNTK
VAEAEMATMEKKGVDTGYKAIHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLTIKPVILAADSSEPD
LSEQALTEKGVLFNSGEFDGLAFEAAFNAIADKLAEKGVGERKVNYRLRDWGVSRQRYWGAPIPMVTLEDGTVLPTPEDQ
LPVILPEDVVMDGITSPIKADPEWAKTTVNGMPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSKAANYWLPVDIYIG
GIEHAIMHLLYFRFFHKLMRDAGMVTSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVERDEKGRIVKAKDAAG
HELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMTLEWQESGVEGANRFIKRVWKLVYEHTAKGPVAAL
NVDALSEDQKALRRDVHKTIAKVTDDIGRRQTFNTAIAAIMELMNKLAKAPQEGEQDRALLQEALQAVVRMLNPFTPHVC
FTLWQELGGEGDIDNAPWPVADEQAMVENTTLVVVQVNGKVRGKITVAVDATEEQVRERAGQEHLVAKYLDGVTVRKVIY
VPGKLLNLVVG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 6e-152 42