Gene Information

Name : safC (SC0294)
Accession : YP_215281.1
Strain : Salmonella enterica SC-B67
Genome accession: NC_006905
Putative virulence/resistance : Virulence
Product : fimbriae usher
Function : -
COG functional category : N : Cell motility
COG ID : COG3188
EC number : -
Position : 338208 - 340718 bp
Length : 2511 bp
Strand : +
Note : IPR000015: Fimbrial biogenesis outer membrane usher protein

DNA sequence :
ATGAAGCTCAAACAACCTGCCTTGCTACTGTTTATCGCGGGAGTGGTTCATTGCGCAAATGCGCACGCTTACACATTCGA
TGCATCAATGTTGGGCGATGCAGCGAAAGGGGTTGATATGTCGCTCTTTAACCAGGGGGTACAACAGCCAGGGACTTATC
GAGTGGACGTGATGGTGAATGGTAAACGTATCGACACCCGTGATGTGGTGTTCAAATTGGAAAAGGATGGGCAAGGAACG
CCTTTTCTGGCTCCTTGTTTGACGGTCAGTCAGCTTTCACGCTACGGCGTAAAAACGGAAGATTACCCTCAGTTGTGGAA
AGCAGCAAAGACCCCAGATGAGTGTGCGGATCTGACCGCCATTCCACAGGCTAAAGCGGTACTGGATATCAATAATCAGC
AACTGCAACTGAGTATTCCGCAGTTGGCATTGCGTACGAAATTTAAGGGGATCGCTCCTGAAGATCTCTGGGATGATGGT
ATTCCGGCGTTTCTGATGAACTACAGTGCGAGGACAATGCAGACGGATTACAAAATGGATATGGGGAGGCGTGACAACTC
TTCCTGGGTACAACTGCAACCGGGAATCAATATAGGTGCGTGGCGTGTCCGCAATGCGACCAGTTGGCAGCGGAGTAGTC
AACTGTCGGGGAAGTGGCAGGCAGCATATACCTATGCTGAGCGTGGACTGTACTCACTAAAAAGTCGTCTGACTCTGGGG
CAAAAGACTTCGCAGGGGGAGATATTTGATAGTGTGCCATTTACCGGTGTGATGTTGGCATCGGATGACAACATGGTGCC
CTACAGTGAGCGGCAGTTTGCTCCGGTAGTGCGTGGGATTGCCCGCACGCAGGCTCGGGTGGAGGTCAAACAGAATGGTT
ACACCATTTACAACACCACTGTGGCGCCCGGACCGTTTGCACTGCGGGATCTGTCGGTAACAGACAGTAGTGGTGATCTG
CATGTCACCGTGTGGGAGGCCGATGGCAGTACACAAATGTTTGTGGTGCCGTATCAGACCCCGGCGATAGCACTGCACCA
GGGATATTTGAAGTACAGCCTGTTGGCGGGCCGATACCGATCGTCAGACTCTGCAACAGATAAGGCGCAGATCGCGCAGG
CTACGTTGATGTATGGTCTGCCGTGGAATCTCACTGCATATGGCGGTATACAGAGTGCAACGCACTATCAAGCTGCATCG
CTTGGTTTGGGGGTATCTCTCGGGCGGTGGGGGAGTTTATCTGTCGATGGAAGCGACACACACAGTCAGCGTCAGGGGGA
AGCGGTACAGCAAGGAGCCTCCTGGCGACTGCGTTACAGCAACCAGCTGACTGCGACGGGAACAAATTTTTCTCTGACGA
GATGGCAGTATGCCTCGCAGGGCTATAACACCTTATCCGATGTGCTCGACAGTTATCGACATGATGGCAACCGTCTATGG
TCGTGGCGGGAAAATTTGCAGCCGAGCTCGCGTACCACCCTGATGTTGAGTCAGTCATGGGGGAGGCATTTGGGCAATCT
GAGTTTAACCGGTTCCCGTACCGACTGGCGTAATCGCCCCGGTCATGATGACAGCTACGGACTGAGTTGGGGAACCTCTA
TCGGAGGGGGCTCGCTGTCATTGAACTGGAATCAAAACAGAACGCTGTGGCGCAATGGCGCGCACCGTAAAGAGAACATA
ACCAGCCTGTGGTTCAGTATGTCATTAAGCCGCTGGACGGGGAATAATGTAAGTGCCAGTTGGCAGATGACTTCACCATC
ACACGGTGGTCAGACGCAACAAGTGGGGGTCAACGGAGAGGCATTCAGTCAGCAACTGGATTGGGAGGTGCGTCAGAGTT
ACCGTGCCGATGCCCCGCCAGGTGGTGGTAATAACAGCGCATTGCACTTGGCATGGAATGGGGGTTACGGCCTGTTAGGT
GGTGACTATAGCTACAGCCGGGCGATGCGCCAGATGGGAGTCAATATCGCGGGAGGTATAGTTATCCACCATCATGGTGT
GACGCTGGGGCAACCTTTGCAAGGCTCAGTGGCGCTGGTTGAAGCGCCAGGGGCCTCGGGGGTGCCAGTTGGCGGCTGGC
CTGGCGTTAAGACGGATTTTCGTGGCGACACCACAGTGGGCAACCTGAGCGTCTATCAGGAGAATACAGTCAGCCTCGAT
CCGTCGCGACTACCGGATGACGCAGAGGTCACACAAACCGATGTGCGCGTGGTGCCAACCGAAGGGGCGGTGGTGGAAGC
GAAGTTTCACACTCGCATCGGGGCCAGGGCACTGATGACGCTGAAACGGGAGGATGGTAGCGCCATTCCTTTCGGGGCGC
AGGTTACAGTCAATGGGCAGGATGGCAGTGCTGATCTGGTGGATACTGATAGCCAGGTTTATCTCACTGGTCTGGCGGAT
AAGGGCGAACTGACGGTGAAATGGGGAGCACAGCAATGTCGGGTTAACTACCACCTACCTGCCCATAAGGGAATCGCGGG
CTTGTATCAAATGAGCGGTCTCTGCAGATAG

Protein sequence :
MKLKQPALLLFIAGVVHCANAHAYTFDASMLGDAAKGVDMSLFNQGVQQPGTYRVDVMVNGKRIDTRDVVFKLEKDGQGT
PFLAPCLTVSQLSRYGVKTEDYPQLWKAAKTPDECADLTAIPQAKAVLDINNQQLQLSIPQLALRTKFKGIAPEDLWDDG
IPAFLMNYSARTMQTDYKMDMGRRDNSSWVQLQPGINIGAWRVRNATSWQRSSQLSGKWQAAYTYAERGLYSLKSRLTLG
QKTSQGEIFDSVPFTGVMLASDDNMVPYSERQFAPVVRGIARTQARVEVKQNGYTIYNTTVAPGPFALRDLSVTDSSGDL
HVTVWEADGSTQMFVVPYQTPAIALHQGYLKYSLLAGRYRSSDSATDKAQIAQATLMYGLPWNLTAYGGIQSATHYQAAS
LGLGVSLGRWGSLSVDGSDTHSQRQGEAVQQGASWRLRYSNQLTATGTNFSLTRWQYASQGYNTLSDVLDSYRHDGNRLW
SWRENLQPSSRTTLMLSQSWGRHLGNLSLTGSRTDWRNRPGHDDSYGLSWGTSIGGGSLSLNWNQNRTLWRNGAHRKENI
TSLWFSMSLSRWTGNNVSASWQMTSPSHGGQTQQVGVNGEAFSQQLDWEVRQSYRADAPPGGGNNSALHLAWNGGYGLLG
GDYSYSRAMRQMGVNIAGGIVIHHHGVTLGQPLQGSVALVEAPGASGVPVGGWPGVKTDFRGDTTVGNLSVYQENTVSLD
PSRLPDDAEVTQTDVRVVPTEGAVVEAKFHTRIGARALMTLKREDGSAIPFGAQVTVNGQDGSADLVDTDSQVYLTGLAD
KGELTVKWGAQQCRVNYHLPAHKGIAGLYQMSGLCR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
safC NP_454907.1 outer-membrane fimbrial usher protein Not tested SPI-6 Protein 0.0 98
afaC AAD44022.2 AfaC Virulence PAI-I AL862 Protein 0.0 49
afaC ADD91743.1 putative AfaC-VIII usher protein Not tested PAI-I AL862 Protein 0.0 49

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
safC YP_215281.1 fimbriae usher VFG0853 Protein 0.0 50
safC YP_215281.1 fimbriae usher VFG0944 Protein 0.0 49
safC YP_215281.1 fimbriae usher VFG0849 Protein 4e-173 46
safC YP_215281.1 fimbriae usher VFG0857 Protein 1e-174 45
safC YP_215281.1 fimbriae usher VFG0419 Protein 7e-171 44