Gene Information

Name : invA (SC2828)
Accession : YP_217815.1
Strain : Salmonella enterica SC-B67
Genome accession: NC_006905
Putative virulence/resistance : Virulence
Product : invasion protein
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG4789
EC number : -
Position : 2991928 - 2993985 bp
Length : 2058 bp
Strand : -
Note : IPR001712: Bacterial type III secretion FHIPEP; IPR006302: Type III secretion protein HrcV

DNA sequence :
GTGCTGCTTTCTCTACTTAACAGTGCTCGTTTACGACCTGAATTACTGATTCTGGTACTAATGGTGATGATCATTTCTAT
GTTCGTCATTCCATTACCTACCTATCTGGTTGATTTCCTGATCGCACTGAATATCGTACTGGCGATATTGGTGTTTATGG
GGTCGTTCTATATTGACAGAATCCTCAGTTTTTCAACGTTTCCTGCGGTACTGTTAATTACCACGCTCTTTCGTCTGGCA
TTATCGATCAGTACCAGCCGTCTTATCTTGATTGAAGCCGATGCCGGTGAAATTATCGCCACGTTCGGGCAATTCGTTAT
TGGCGATAGCCTGGCGGTGGGTTTTGTTGTCTTCTCTATTGTCACCGTGGTTCAGTTTATCGTTATTACCAAAGGTTCAG
AACGCGTCGCGGAAGTCGCGGCCCGATTTTCTCTGGATGGTATGCCCGGTAAACAGATGAGTATTGATGCCGATTTGAAG
GCCGGTATTATTGATGCGGATGCCGCGCGCGAACGGCGAAGCGTACTGGAAAGGGAAAGCCAGCTTTACGGTTCCTTTGA
CGGTGCGATGAAGTTTATCAAAGGTGACGCTATTGCCGGCATCATTATCATCTTTGTGAACTTTATTGGCGGTATTTCGG
TGGGGATGACCCGCCATGGTATGGATTTGTCCTCCGCTCTGTCTACTTATACCATGCTGACCATTGGTGATGGTCTTGTC
GCCCAGATCCCCGCATTGTTGATTGCGATTAGTGCCGGTTTTATCGTGACCCGCGTAAATGGCGATAGCGATAATATGGG
GCGGAATATCATGACGCAGCTGTTGAACAACCCATTTGTATTGGTTGTTACGGCTATTTTGACCATTTCAATGGGAACTC
TGCCGGGATTCCCGCTGCCGGTATTTGTTATTTTATCGGTGGTTTTAAGCGTACTCTTCTATTTTAAATTCCGTGAAGCA
AAACGTAGCGCCGCCAAACCTAAAACCAGTAAAGGCGAGCAGCCGCTCAGTATTGAGGAAAAAGAAGGGTCGTCGTTAGG
ACTGATTGGCGATCTCGATAAAGTCTCTACAGAGACCGTACCGTTGATATTACTTGTGCCGAAGAGCCGGCGTGAAGATC
TGGAAAAAGCTCAACTTGCGGAGCGTCTACGTAGTCAGTTCTTTATTGATTATGGCGTGCGCCTGCCGGAAGTATTGTTA
CGCGATGGAGAGGGCCTGGACGATAACAGCATCGTATTGTTGATTAATGAGATCCGTGTTGAACAATTTACGGTCTATTT
TGATTTGATGCGAGTGGTAAATTATTCCGATGAAGTCGTGTCCTTTGGTATTAATCCAACAATCCATCAGCAAGGTAGCA
GCCAGTATTTCTGGGTAACGCATGAAGAGGGGGAGAAACTCCGGGAGCTTGGCTATGTGTTGCGGAACGCGCTTGATGAG
CTTTACCACTGTCTGGCGGTGACGCTGGCGCGCAACGTCAATGAATATTTCGGTATTCAGGAAACAAAACATATGTTGGA
CCAACTGGAAGCGAAATTTCCTGATTTACTTAAAGAAGTGCTCAGACATGCCACGGTACAACGTATATCTGAAGTTTTGC
AGCGTTTGTTAAGTGAACGTGTTTCCGTGCGTAATATGAAATTAATTATGGAAGCGCTCGCATTGTGGGCGCCAAGAGAA
AAAGATGTCATTAACCTTGTGGAGCATATTCGTGGGGCAATGGCGCGTTATATTTGCCATAAATTCGCCAATGGCGGCGA
ATTACGAGCAGTAATGGTATCTGCTGAAGTTGAGGATGTTATTCGCAAAGGGATCCGTCAGACCTCTGGCAGTACCTTCC
TCAGCCTTGACCCGGAAGCCTCCGCTAATTTGATGGATCTCATTACACTTAAGTTGGATGATTTATTGATTGCACATAAA
GATCTTGTCCTCCTTACGTCTGTCGATGTCCGTCGATTTATTAAGAAAATGATTGAAGGTCGTTTTCCGGATCTGGAGGT
TTTATCTTTCGGTGAGATAGCTGATAGCAAGTCAGTGAATGTTATAAAAACAATATAA

Protein sequence :
MLLSLLNSARLRPELLILVLMVMIISMFVIPLPTYLVDFLIALNIVLAILVFMGSFYIDRILSFSTFPAVLLITTLFRLA
LSISTSRLILIEADAGEIIATFGQFVIGDSLAVGFVVFSIVTVVQFIVITKGSERVAEVAARFSLDGMPGKQMSIDADLK
AGIIDADAARERRSVLERESQLYGSFDGAMKFIKGDAIAGIIIIFVNFIGGISVGMTRHGMDLSSALSTYTMLTIGDGLV
AQIPALLIAISAGFIVTRVNGDSDNMGRNIMTQLLNNPFVLVVTAILTISMGTLPGFPLPVFVILSVVLSVLFYFKFREA
KRSAAKPKTSKGEQPLSIEEKEGSSLGLIGDLDKVSTETVPLILLVPKSRREDLEKAQLAERLRSQFFIDYGVRLPEVLL
RDGEGLDDNSIVLLINEIRVEQFTVYFDLMRVVNYSDEVVSFGINPTIHQQGSSQYFWVTHEEGEKLRELGYVLRNALDE
LYHCLAVTLARNVNEYFGIQETKHMLDQLEAKFPDLLKEVLRHATVQRISEVLQRLLSERVSVRNMKLIMEALALWAPRE
KDVINLVEHIRGAMARYICHKFANGGELRAVMVSAEVEDVIRKGIRQTSGSTFLSLDPEASANLMDLITLKLDDLLIAHK
DLVLLTSVDVRRFIKKMIEGRFPDLEVLSFGEIADSKSVNVIKTI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
invA YP_217815.1 invasion protein Virulence SPI-1 Protein 0.0 100
invA NP_457290.1 possible secretory protein (associated with virulence) Virulence SPI-1 Protein 0.0 100
invA NP_806499.1 virulence-associated secretory protein Virulence SPI-1 Protein 0.0 100
invA NP_461817.1 needle complex export protein Virulence SPI-1 Protein 0.0 100
ECs3731 NP_311758.1 EivA Not tested LIM Protein 3e-179 65
invA AAS66860.1 InvA Not tested SSR-2 Protein 3e-166 64
ysaV AAS66840.1 YsaV Not tested SSR-1 Protein 7e-144 55
lssD AAO18050.1 LssD Virulence TTSS locus Protein 1e-95 42
YPO0266 YP_002345347.1 secretion system apparatus protein SsaV Virulence Not named Protein 4e-88 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
invA YP_217815.1 invasion protein VFG0557 Protein 0.0 100
invA YP_217815.1 invasion protein VFG1006 Protein 4e-171 65
invA YP_217815.1 invasion protein VFG1780 Protein 6e-144 54
invA YP_217815.1 invasion protein VFG0064 Protein 1e-97 43
invA YP_217815.1 invasion protein VFG0384 Protein 4e-99 43
invA YP_217815.1 invasion protein VFG0198 Protein 2e-93 42