Gene Information

Name : spaS (SC2819)
Accession : YP_217806.1
Strain : Salmonella enterica SC-B67
Genome accession: NC_006905
Putative virulence/resistance : Virulence
Product : surface presentation of antigens protein SpaS
Function : -
COG functional category : N : Cell motility
COG ID : COG1377
EC number : -
Position : 2985061 - 2986131 bp
Length : 1071 bp
Strand : -
Note : Required for surface presentation of invasion plasmid antigens; required for invasion and for secretion of the three ipa proteins

DNA sequence :
ATGTCCTCGAATAAAACAGAAAAACCGACTAAAAAACGGCTGGAAGACTCTGCTAAAAAAGGCCAGTCATTTAAAAGTAA
AGATCTCATTATCGCCTGCCTGACGCTGGGAGGAATTGCCTATCTGGTGTCGTATGGCTCATTTAATGAGTTTATGGGGA
TAATTAAGATCATTATTGCGGATAATTTTGATCAGAGCATGGCTGATTACAGTTTGGCCGTTTTTGGGATAGGATTAAAA
TATCTGATTCCATTTATGCTGCTCTGTTTAGTGTGTTCCGCATTACCGGCGTTATTACAGGCCGGTTTCGTGCTGGCGAC
AGAAGCATTAAAACCTAATTTATCGGCGTTAAACCCGGTAGAAGGGGCGAAAAAACTTTTTAGTATGCGCACGGTTAAAG
ATACGGTCAAAACCCTACTGTATCTCTCATCCTTTGTGGTGGCCGCCATCATTTGCTGGAAGAAATATAAGGTTGAAATC
TTTTCTCAGTTAAATGGCAATGTTGTGGATATTGCCGTCATTTGGCGTGAACTTCTCCTCGCATTGGTATTAACTTGCCT
TGCTTGCGCATTGATTGTCTTATTATTGGATGCTGTTGCGGAATATTTCCGGACCATGAAAGATATGAAAATGGATAAGG
AAGAAGTGAAGCGTGAAATGAAGGAGCAGGAAGGGAACCCAGAGGTTAAATCTAAAAGACGTGAAGTTCATATGGAAATT
CTGTCTGAACAGGTGAAATCCGATATTGAAAACTCACGCCTGATTGTTGCCAACCCCACGCATATTACGATCGGGATTTA
TTTTAAACCCGAATTGATGCCGATTCCGATGATCTCGGTGTATGAAACGAATCAGCGCGCGCTGGCCGTCCGCGCCTATG
CGGAGAAGGTTGGCGTACCTGTGATCGTCGATATCAAACTGGCGCGCAGTCTTTTCAAAACCCATCGCCGTTATGATCTG
GTGAGTCTGGAAGAAATTGATGAAGTTTTACGTCTTCTGGTTTGGCTGGAAGAGGTAGAAAACGCGGGCAAAGACGTTAT
TCAGCCACAAGAAAACGAGGTACGGCATTGA

Protein sequence :
MSSNKTEKPTKKRLEDSAKKGQSFKSKDLIIACLTLGGIAYLVSYGSFNEFMGIIKIIIADNFDQSMADYSLAVFGIGLK
YLIPFMLLCLVCSALPALLQAGFVLATEALKPNLSALNPVEGAKKLFSMRTVKDTVKTLLYLSSFVVAAIICWKKYKVEI
FSQLNGNVVDIAVIWRELLLALVLTCLACALIVLLLDAVAEYFRTMKDMKMDKEEVKREMKEQEGNPEVKSKRREVHMEI
LSEQVKSDIENSRLIVANPTHITIGIYFKPELMPIPMISVYETNQRALAVRAYAEKVGVPVIVDIKLARSLFKTHRRYDL
VSLEEIDEVLRLLVWLEEVENAGKDVIQPQENEVRH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
spaS YP_217806.1 surface presentation of antigens protein SpaS Virulence SPI-1 Protein 1e-133 100
spaS NP_457281.1 secretory protein (associated with virulence) Virulence SPI-1 Protein 2e-132 99
spaS NP_806490.1 surface presentation of antigens protein SpaS Virulence SPI-1 Protein 2e-132 99
spaS NP_461808.1 surface presentation of antigens protein SpaS Virulence SPI-1 Protein 4e-132 99
spaS AAS66868.1 SpaS Not tested SSR-2 Protein 2e-66 55
ECs3721 NP_311748.1 surface presentation of antigens protein SpaS Not tested LIM Protein 5e-58 53
ysaU AAS66849.1 YsaU Not tested SSR-1 Protein 2e-42 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
spaS YP_217806.1 surface presentation of antigens protein SpaS VFG0548 Protein 2e-132 99
spaS YP_217806.1 surface presentation of antigens protein SpaS VFG1015 Protein 2e-50 49
spaS YP_217806.1 surface presentation of antigens protein SpaS VFG2452 Protein 4e-47 45