Gene Information

Name : smpB (SC2688)
Accession : YP_217675.1
Strain : Salmonella enterica SC-B67
Genome accession: NC_006905
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 2843616 - 2844143 bp
Length : 528 bp
Strand : +
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
ATGGGGTGTTTTCGATATCAGATTACCTATGAATTCACGACACTTATGACGAAGAAAAAAGCACATAAACCGGGCTCAGC
CACCATCGCGCTGAATAAGCGCGCCCGGCACGAATACTTTATCGAAGAAGAGTTCGAGGCTGGTCTCGCCCTGCAAGGCT
GGGAAGTAAAATCTCTGCGCGCAGGAAAAGCCAATATCGGCGACAGTTACGTTATCCTCAAAGATGGCGAGGCCTGGCTG
TTTGGCGCAAACTTTACGCCGATGGCGGTCGCCTCGACACATGTCGTATGCGACCCAACCCGAACCCGCAAACTGTTGTT
AAATCAGCGTGAGCTTGATTCACTGTATGGCCGTATTAATCGTGAAGGTTATACTGTCGTCGCGCTTTCTCTGTACTGGA
AAAATGCCTGGTGCAAAGTGAAGATCGGCGTGGCGAAAGGTAAAAAACAACATGATAAACGTTCCGATCTTAAAGAACGT
GAGTGGCAACTGGATAAAGCACGCATTATGAAAAATGCAGGCCGATAA

Protein sequence :
MGCFRYQITYEFTTLMTKKKAHKPGSATIALNKRARHEYFIEEEFEAGLALQGWEVKSLRAGKANIGDSYVILKDGEAWL
FGANFTPMAVASTHVVCDPTRTRKLLLNQRELDSLYGRINREGYTVVALSLYWKNAWCKVKIGVAKGKKQHDKRSDLKER
EWQLDKARIMKNAGR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
smpB NP_230495.1 SsrA-binding protein Not tested VPI-1 Protein 6e-51 71
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 7e-25 47
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 7e-21 43