Gene Information

Name : topB (SC1320)
Accession : YP_216307.1
Strain : Salmonella enterica SC-B67
Genome accession: NC_006905
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0550
EC number : -
Position : 1417586 - 1419592 bp
Length : 2007 bp
Strand : +
Note : decatenates replicating daughter chromosomes

DNA sequence :
TTGGCGAACTGGTCGAGGCCCGCGGCGGTCGCGCTATGGTTGAGATTCGTTAACCTGATGCGGTTGTTTATTGCCGAAAA
ACCGAGTCTGGGGCGCGCCATTGCGGATGTGCTGCCAAAACCGCACCGTAAAGGCGATGGTTTTATTGAGTGCGGAAACG
GGCAGGTCGTCACCTGGTGTATTGGTCATTTGCTGGAACAGGCGCAGCCGGATGCGTATGACAGCCGTTATGCGCGCTGG
AATCTGGCTGACCTGCCTATCGTGCCGGAAAAATGGCAGCTTCAGCCTCGTCCTTCCGTCACCAAACAGCTCAATGTGAT
TAAGCGCTTTTTGCATCAAGCCGGTGAAATTATTCACGCTGGCGACCCGGATCGCGAAGGGCAGCTTCTGGTTGATGAAG
TGCTGGATTATCTCCAGCTTCCTGCCGAAAAGCGCCAACAGGTGCGGCGTTGTCTGATAAACGACCTTAACCCGCAGGCG
GTCGAGCGTGCTATCGACAGGCTGCGAGCGAACAGCGACTTCGTGCCGCTGTGCGTCTCCGCGCTGGCGCGAGCGCGAGC
GGACTGGCTGTATGGCATTAATATGACCCGCGCTTACACGATCCTGGGCCGTAATGCTGGCTATCAGGGCGTGTTATCCG
TGGGACGCGTACAGACGCCGGTACTGGGGCTGGTGGTGCGGCGAGACGAAGAGATTGAGAACTTCGTCGCCAAAGACTTC
TTTGAAGTGAAGGCGCACATCGTTACGCCTGCCGACGAGCGTTTTACCGCTATCTGGCAGCCGAGCGAGGCGTGCGAACC
TTATCAGGATGAAGAAGGGCGCTTGCTGCATCGTCCGCTGGCGGAGCATGTGGTGAACCGAATCAACGGTCAGCCCGCGC
TGGTAACCAGTTATAATGATAAACGGGAATCAGAATCCGCGCCGCTGCCGTTTTCGCTCTCGACGCTACAGATTGAAGCC
GCTAAACGCTTTGGCCTGAGCGCGCAAAACGTGCTTGATATTTGTCAGAAGCTATATGAAACCCACAAACTGATTACCTA
TCCGCGTTCCGACTGCCGTTATCTGCCGGAAGAACACTTTGCCGGACGGCAGGCGGTCATGAACGCGATTAGCGTCCACG
CCCCGGATTTACTGCCGCAGCCTGTGGTTAATCCTGATACGCGCAATCGCTGCTGGGATGACAAAAAAGTGGATGCGCAC
CACGCGATTATCCCGACGGCGCGCAGTTCTTCTGTCCATCTGACGGAAAACGAAGCGAAAGTGTACACCCTGATTGCGCG
TCAGTATCTGATGCAGTTCTGCCCGGACGCGGTGTTTCGTAAATGCGTTATTGAACTGGAAATCGCCAAAGGGAAATTTG
TCGCCAAAGCGCGTTTTCTGGCGGAGGCCGGTTGGCGGACGTTACTGGGCAGTAAAGAGCGCGACGAGGAAAACGACGGT
ACGCCGCTGCCGGTTGTCGCCAAAGGTGATGAGTTGCTGTGTGAAAAGGGGGAAGTGGTCGAGCGCCAAACCCAGCCGCC
GCGTCATTTCACTGATGCGACATTGCTTTCCGCGATGACCGGAATTGCCCGCTTCGTGCAGGATAAAGATCTGAAAAAGA
TCCTGCGCGCGACCGATGGGCTGGGGACGGAAGCCACGCGCGCCGGGATTATCGAGCTGCTGTTCAAACGTAGCTTTCTG
ACCAAAAAAGGGCGCTACATTCATTCTACCGATGCTGGCAAAGCGTTAATACATTCGCTGCCGGAAATGGCGGCCCGTCC
AGATATGACCGCGCACTGGGAATCTGTTTTGACGCAAATCAGCGAAAAGCAGTGCCGTTACCAGGATTTCATGCAACCGC
TGGTCGGCACGTTATATCAGCTGATCGAGCAGGCTAAGCGCACGCCGGTGAAGCGCTTCAGAGGGATAGTCGCGCCAGGC
GGTGGAGACAAGAAAAAGAGCGCGCCGCGTAAGCGAGCGGGCAAAAAAAGCCCGCCTGCTAAGGAGACAGGCCGTCAGAC
CGAATAA

Protein sequence :
MANWSRPAAVALWLRFVNLMRLFIAEKPSLGRAIADVLPKPHRKGDGFIECGNGQVVTWCIGHLLEQAQPDAYDSRYARW
NLADLPIVPEKWQLQPRPSVTKQLNVIKRFLHQAGEIIHAGDPDREGQLLVDEVLDYLQLPAEKRQQVRRCLINDLNPQA
VERAIDRLRANSDFVPLCVSALARARADWLYGINMTRAYTILGRNAGYQGVLSVGRVQTPVLGLVVRRDEEIENFVAKDF
FEVKAHIVTPADERFTAIWQPSEACEPYQDEEGRLLHRPLAEHVVNRINGQPALVTSYNDKRESESAPLPFSLSTLQIEA
AKRFGLSAQNVLDICQKLYETHKLITYPRSDCRYLPEEHFAGRQAVMNAISVHAPDLLPQPVVNPDTRNRCWDDKKVDAH
HAIIPTARSSSVHLTENEAKVYTLIARQYLMQFCPDAVFRKCVIELEIAKGKFVAKARFLAEAGWRTLLGSKERDEENDG
TPLPVVAKGDELLCEKGEVVERQTQPPRHFTDATLLSAMTGIARFVQDKDLKKILRATDGLGTEATRAGIIELLFKRSFL
TKKGRYIHSTDAGKALIHSLPEMAARPDMTAHWESVLTQISEKQCRYQDFMQPLVGTLYQLIEQAKRTPVKRFRGIVAPG
GGDKKKSAPRKRAGKKSPPAKETGRQTE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pph56 CAI36097.1 Topoisomerase IA Not tested PPHGI-1 Protein 1e-102 41
topB1 YP_005176228.1 DNA topoisomerase III Not tested ICEPmu1 Protein 6e-110 41