Gene Information

Name : tktB (VF_A0686)
Accession : YP_206644.1
Strain :
Genome accession: NC_006841
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 758176 - 760167 bp
Length : 1992 bp
Strand : +
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
ATGAACCGTAAACATCTAGCAAATGCAATCCGTGCTCTAAGCATGGACGGCGTACAACAAGCAAACTCTGGCCACCCTGG
CGCACCTATGGGCATGGCTGATATCGCTGAAGTTCTTTGGCGTTCTCATTTAAATCACAACCCAGCAAACCCAGAGTGGG
CTGACCGCGACCGTTTTATTCTTTCAAACGGTCATGGCTCTATGCTGATTTACTCTCTGCTTCACCTTTCAGGTTACGAG
TTATCAATTGATGACCTTAAAAACTTCCGTCAACTTCACTCTAAAACTCCGGGTCACCCAGAGTATGGCTATGCGCCAGG
TGTTGAAACAACTACAGGTCCTCTAGGTCAAGGTATTACCAATGCTGTTGGTATGGCGATGGCTGAAAAAGCATTAGCGG
CACAATTCAACAAAGAAGGCCACGATATCGTTGACCACTTCACTTATACATTTATGGGTGATGGCTGTCTGATGGAAGGT
ATTTCTCACGAAGCGTGTTCACTTGCTGGTACGTTAGGCCTAGGCAAATTAATCGCATTCTGGGATGACAACGGTATCTC
TATCGATGGTGAAGTTGAAGGTTGGTTCTCTGATGACACACCTAAACGCTTTGAAGCGTACGGCTGGCACGTAATTCCTG
CTGTTGATGGTCATGATTCAGATGCTATCAATGCAGCAATTGAAGCGGCTAAAGCCGATCCTCGCCCTACTCTTATTTGT
ACGAAAACTATTATCGGTTTTGGTTCTCCTAACAAACAAGGTACACACGACTGTCACGGTGCTCCACTAGGCGCTGACGA
AATTAAAGCAGCAAAAGCACAATTAGGTTGGGAGCACGGCGCATTTGAAATTCCGCAAGAAGTTTACGCAGAATGGGACG
CGAAAGAAACAGGCGCAGCTAAGGAAGCGTCGTGGAACGAGAAATTTGCAGCTTATGAAGCAGCATACCCAGAACTTGCA
GCCGAATTTACTCGCCGCGTAAACGGTGATTTACCAAAAGAGTGGGAAGAAAAAGCATCAGCAATCATTGCTGATCTTCA
AGCTAACCCTGCAAACATCGCATCACGTAAAGCGTCTCAAAACGCATTAGAAGCATTTGGTGCTATGTTACCTGAATTCA
TGGGCGGCTCTGCTGATCTTGCACCTTCTAACCTAACAATGTGGTCTGGTTCTAAGTCTCTAGAAGCAAACGACTTCTCT
GGTAATTACATTCATTACGGTGTTCGTGAATTTGGTATGACAGCAATCATGAATGGTATTGCTCTGCACGGTGGTTTCGT
ACCATACGGCGCAACGTTCCTAATGTTCATGGAATACGCTCGTAACGCAATGCGTATGGCTGCACTAATGAAAGTGCAAA
ACATCCAAGTTTACACGCACGACTCTATCGGTCTTGGCGAAGATGGTCCAACTCACCAGCCAGTTGAGCAAATTGCTTCT
CTACGTCTAACTCCTAACATGAGCACATGGCGTCCATGTGACCAAGTTGAGTCAGCTGTAGCATGGAAACTAGCTATCGA
GCGTAAAGATGGTCCATCTGCACTTATCTTCTCTCGTCAAAACCTTGCACAACAAGAGCGTGATGCAAAGCAATTAGCGA
ACATCGCTAAAGGTGGCTATATCCTTAAAGATTGTGAAGGTCAACCAGAGTTAATCCTTATTGCAACGGGTTCAGAAGTT
GAACTAGCAATTGAAGCAGCAGCACAACTGACAGCAGAAGGTAAAGCGGTACGTGTTGTTTCAATGCCATCAACAGATGC
ATTTGATAAGCAAGACGAAGCATACCGTGAAGCAGTACTTCCATCAGCGGTAACTAAACGTATCGCAATTGAAGCGGGTA
TTGCTGATTTCTGGTACAAGTACGTAGGTTTCGGTGGCAAGATCATCGGCATGACAACATTTGGTGAGTCAGCACCTGCT
GATGAGCTATTCAAAATGTTTGGTTTCACTACTGAAAACGTAGTAAACACGGCAAAAGAATTGTTAGCTTAA

Protein sequence :
MNRKHLANAIRALSMDGVQQANSGHPGAPMGMADIAEVLWRSHLNHNPANPEWADRDRFILSNGHGSMLIYSLLHLSGYE
LSIDDLKNFRQLHSKTPGHPEYGYAPGVETTTGPLGQGITNAVGMAMAEKALAAQFNKEGHDIVDHFTYTFMGDGCLMEG
ISHEACSLAGTLGLGKLIAFWDDNGISIDGEVEGWFSDDTPKRFEAYGWHVIPAVDGHDSDAINAAIEAAKADPRPTLIC
TKTIIGFGSPNKQGTHDCHGAPLGADEIKAAKAQLGWEHGAFEIPQEVYAEWDAKETGAAKEASWNEKFAAYEAAYPELA
AEFTRRVNGDLPKEWEEKASAIIADLQANPANIASRKASQNALEAFGAMLPEFMGGSADLAPSNLTMWSGSKSLEANDFS
GNYIHYGVREFGMTAIMNGIALHGGFVPYGATFLMFMEYARNAMRMAALMKVQNIQVYTHDSIGLGEDGPTHQPVEQIAS
LRLTPNMSTWRPCDQVESAVAWKLAIERKDGPSALIFSRQNLAQQERDAKQLANIAKGGYILKDCEGQPELILIATGSEV
ELAIEAAAQLTAEGKAVRVVSMPSTDAFDKQDEAYREAVLPSAVTKRIAIEAGIADFWYKYVGFGGKIIGMTTFGESAPA
DELFKMFGFTTENVVNTAKELLA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 0.0 78
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 0.0 69