Gene Information

Name : hemC (VF_0066)
Accession : YP_203449.1
Strain :
Genome accession: NC_006840
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 73741 - 74676 bp
Length : 936 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence : 
ATGTCACAGCAATTACCTGTTCGTATCGCCACTCGTAAAAGCCCTTTGGCTCTATGGCAAGCCCACTTTGTTAAAGATGC
ACTACAAGCCGCTCACCCAGGTTTGGAAGTTGAATTGGTTACTATGGTAACGAAAGGCGACATTATTCTTGATACGCCAT
TAGCAAAAGTTGGCGGAAAAGGCTTATTCGTTAAAGAACTTGAAGTTGCGATGCTAGAAGGCCGCGCAGACCTTGCTGTT
CACTCAATGAAAGACGTGCCAGTTGAATTTCCTGAAGGTCTAGGTCTTGTTACGATTTGTGAGCGTGAAGACCCACGTGA
CGCATTTGTATCGAACACTTACAACAATATTGATGAGTTACCTCAAGGCGCCGTTGTTGGTACTTGTAGCCTACGTCGTC
AATGCCAACTTAAAGAAGCTCGTCCTGATCTTATTATCAAAGAATTACGCGGTAATGTGGGAACTCGTCTACAAAAACTG
GATGATGGTAACTACGATGCGATCATTCTTGCTTGTGCTGGTTTAATTCGTTTAGGTCTAGAAGACCGAATCAAAAGTGC
AATCGAACCTGAGCAATCATTACCTGCTGTAGGTCAAGGTGCCGTTGGTATTGAAGCTCGCTTAGATGACGATCGCCTTC
GTGCTTTACTTGAACCTCTAAATCACCCAGAAACAGCAAACCGAGTTCTGTGTGAACGTGCGATGAATAATCGCCTAGAA
GGTGGTTGCCAAGTACCAATCGGTAGCTACTCACTAATTGATGGTGACCAAATTTGGTTACGTGCTCTTGTTGGCGAACC
TGATGGCTCAGTGATGATCCGTGGTGAAGTATCTGGACCGGTTTCTGACGCGGAAGCTTTAGGTACTCAACTTGCAGATC
AACTTTTAAACGATGGCGCGAAAGAAATTTTAGAACGCCTATACGCAGAAGCGTAA

Protein sequence : 
MSQQLPVRIATRKSPLALWQAHFVKDALQAAHPGLEVELVTMVTKGDIILDTPLAKVGGKGLFVKELEVAMLEGRADLAV
HSMKDVPVEFPEGLGLVTICEREDPRDAFVSNTYNNIDELPQGAVVGTCSLRRQCQLKEARPDLIIKELRGNVGTRLQKL
DDGNYDAIILACAGLIRLGLEDRIKSAIEPEQSLPAVGQGAVGIEARLDDDRLRALLEPLNHPETANRVLCERAMNNRLE
GGCQVPIGSYSLIDGDQIWLRALVGEPDGSVMIRGEVSGPVSDAEALGTQLADQLLNDGAKEILERLYAEA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 9e-81 61
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 9e-81 61