Gene Information

Name : alr (VF_0302)
Accession : YP_203685.1
Strain :
Genome accession: NC_006840
Putative virulence/resistance : Unknown
Product : alanine racemase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0787
EC number : 5.1.1.1
Position : 310875 - 311957 bp
Length : 1083 bp
Strand : +
Note : converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer

DNA sequence :
ATGAGTTATATGAAAGCGGCCACAGCGCAGATTGATATGTCTGCACTTGCCCACAATTTGCAAAAGATTAAACAACAAGC
TCCGAGTAGTAAATTACTGGCTGTTGTAAAAGCAAATGGGTATGGCCATGGATTGCTGAATATCGCTAAAGGAGCTCAAG
GAGCTGATGCATTTGGTGTCGCTCGTATTGAAGAGGCGCTGCAGCTTCGAGCTGGCGGTATTGTAAAACCTATTTTATTA
CTTGAAGGGTTCTACTCAGCAGGTGACTTGCCTATTTTGGTGACTAATAACATTCAAACGGCGATTCATTGTAAAGAGCA
GTTAGAAGCATTAGAAAGTACAGACTTAGAATTTCCAGTCGTTGCTTGGTTAAAAGTAGATTCAGGTATGCACCGTTTAG
GTATTCGTCCTGAAGAGTTTCAAGAATATGTTGATAGACTACATGCTTGTAAGAATGTCGCTAAACCTTTGCGTTATATG
AGCCACTTTGGCTGTGCGGATGAACTTGATAGTTCAACGACAACAGAGCAAATCGATACCTTTATGTCGCTAACAAAAGG
GTGTCAGGGAGAGCGTTCTCTTGCTGCATCTGCAGGCTTATTAGCTTGGCCTGATAGTCGTTTAGATTGGGTTCGTCCTG
GCATTATTATGTATGGCGTTTCTCCATTTGCAGAACAATCAGCACAAGAGTTGGGTTATTTGCCTACGATGACTCTTACC
TCTCACTTGATCGCAGTTCGTGATGTAAAAGCGGGTGAAAGTGTTGGTTATGGTGCCATTTGGACCAGTGAGCGTGATAC
TAAAATTGGTGTTATTGCGATTGGCTATGGTGATGGGTACCCTCGAACGGCTCCAAATGGTACGCCTGTGTTAGTTAATG
GTCGTAAAGTCCCTATTGCGGGTCGAGTGTCTATGGACATGTTGACCGTTGATTTAGGTCCAGATGCTCAAGATAAAGTG
GGAGATGAAGCCATTTTATGGGGACGAGATCTGCCTTCTGAAGAAGTCGCAGAGCATATTGGAACTATTGCCTACGAGTT
AGTGACTAAATTAACATCACGTGTGCAAATGCAATACACCTAA

Protein sequence :
MSYMKAATAQIDMSALAHNLQKIKQQAPSSKLLAVVKANGYGHGLLNIAKGAQGADAFGVARIEEALQLRAGGIVKPILL
LEGFYSAGDLPILVTNNIQTAIHCKEQLEALESTDLEFPVVAWLKVDSGMHRLGIRPEEFQEYVDRLHACKNVAKPLRYM
SHFGCADELDSSTTTEQIDTFMSLTKGCQGERSLAASAGLLAWPDSRLDWVRPGIIMYGVSPFAEQSAQELGYLPTMTLT
SHLIAVRDVKAGESVGYGAIWTSERDTKIGVIAIGYGDGYPRTAPNGTPVLVNGRKVPIAGRVSMDMLTVDLGPDAQDKV
GDEAILWGRDLPSEEVAEHIGTIAYELVTKLTSRVQMQYT

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
dadX AAC61705.1 alanine racemase Not tested PAI I CFT073 Protein 8e-58 42