Gene Information

Name : argH (VF_2303)
Accession : YP_205686.1
Strain :
Genome accession: NC_006840
Putative virulence/resistance : Unknown
Product : bifunctional argininosuccinate lyase/N-acetylglutamate synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0165
EC number : 2.3.1.1
Position : 2586654 - 2588528 bp
Length : 1875 bp
Strand : -
Note : catalyzes the formation of arginine from (N-L-arginino)succinate and the formation of N-acetylglutamate from glutamate and acetyl-CoA

DNA sequence :
ATGGCATTATGGGGCGGACGTTTTAGTCAAGCAGCAGACACCAGATTCAAACAGTTTAACGATTCACTTCGTATTGATTA
CCGCCTTGCAGAACAAGATATTGTTGGTTCGATTGCATGGTCTAAAGCATTGCTTTCAGTAGGTGTAATTACCGAACTTG
AGCAGCAAAAGCTTGAATTAGCACTGAATGAATTAAAATTAGAAGTAATGGAAGATCCTGAACAGATCTTATTGTCTGAT
GCTGAAGATATTCACAGTTGGGTAGAAACTCAATTGATTGGTAAAGTCGGTGACTTAGGTAAAAAACTCCATACTGGCCG
TTCTCGTAATGATCAAGTAGCAACAGATTTAAAGCTTTGGTGTCGTCAACAAGGACATCAACTACTGCGTACACTTGATC
AACTTCTTAATCAATTAGTAAACGTAGCAAGTGAGCATCAAGCGACAGTACTTCCGGGTTATACGCACTTACAACGTGCA
CAGCCTGTGACTTTTGCTCATTGGTGTTTAGCTTATGTTGAGATGATTGAGCGTGATTATTCTCGTCTTGAAGATGCAAT
TAATCGTTTAGATACTTGTCCGTTAGGCTCTGGAGCTCTTGCTGGCACTGCTTATCCTATGGATCGTGAAAAGCTGGCTC
GTAACCTTGGATTCCAACGTGCAACACGTAATAGTTTAGATTCGGTATCTGATCGTGATCATGTCATGGAACTCATGTCG
ATCGCTTCCATTTCAATGTTGCACCTTTCTCGTCTTGCTGAAGACATGATTTTTTACAATTCAGGTGAATCGAATTTTAT
CGAATTGGCTGATACCGTGACTTCAGGCTCATCACTTATGCCGCAGAAGAAAAACCCAGATGCATTGGAGTTGATCCGTG
GTAAGTGTGGACGTGTATATGGTGCAATGGCTGGCATGATGATGACAGTAAAAGCATTGCCACTGGCTTACAACAAAGAC
ATGCAAGAAGACAAAGAAGGCTTATTTGATGCCTTGGATAGCTGGTCTGATTGTATTGAAATGGCTGCGTTGTGCTTTGA
AGGTATTAAGATTAATGGGGAACGTACGCTTGAAGCAGCAAAACAAGGGTATGCAAACTCAACAGAACTGGCTGATTACT
TGGTAGCGAAAGGCATTCCGTTCCGTGAAGCTCACCATATTGTTGGTGTTGCCGTTGTCGGTGCGATTGAAAAAGGCTGT
GCATTAGAAGAACTTTCTCTTGCTGAACTGAAAGCGTTCTCTGAAGTGATTGAAGACGATGTGTATGAAATCCTCACCAT
TGAATCTTGCCTTGCAAAACGTTGTGCATTAGGTGGCGTTGCTCCTGAGCAAGTTGCGTATGCCGTTGAGCAAGCAGGTA
AACGTCTACAAGAGCGTGATAATGCTGGTGTGAAGGTTCGTCCAGCTCGTTTAACTGATTTAGATGCACTGGAAGGTATG
GTTGCATACTGGGCTGGGCTTGGTGAAAACTTACCGCGTAATCGTAATGAATTAGTACGTGATATTGGCTCATTTGCTGT
GGCAGAGCATCATGGAGAAGTGACAGGCTGTGCCTCTTTGTATGTGTATGACTCAGGACTTGCAGAAATTCGTTCATTAG
GTGTTGAAGCTGGGTGGCAGAGTCAAGGTCAAGGTAAAGCCATTGTTCAGCATTTAGTTGAAAAAGCACGTGAGATGGCG
ATTAAGAAAGTTTTTGTATTAACTCGTGTTCCAGAGTTCTTTATGAAACAAGACTTTATTCCTACCTCTCGTTCATTGTT
GCCAGAAAAGGTGCTGAAAGACTGTGATCAATGTCCACGTCAACATGCGTGTGATGAGGTTGCACTAGAAGTGAATCTAC
AAGAGCAAGTGATCATTAAAAGCAGTGTAGCTTAG

Protein sequence :
MALWGGRFSQAADTRFKQFNDSLRIDYRLAEQDIVGSIAWSKALLSVGVITELEQQKLELALNELKLEVMEDPEQILLSD
AEDIHSWVETQLIGKVGDLGKKLHTGRSRNDQVATDLKLWCRQQGHQLLRTLDQLLNQLVNVASEHQATVLPGYTHLQRA
QPVTFAHWCLAYVEMIERDYSRLEDAINRLDTCPLGSGALAGTAYPMDREKLARNLGFQRATRNSLDSVSDRDHVMELMS
IASISMLHLSRLAEDMIFYNSGESNFIELADTVTSGSSLMPQKKNPDALELIRGKCGRVYGAMAGMMMTVKALPLAYNKD
MQEDKEGLFDALDSWSDCIEMAALCFEGIKINGERTLEAAKQGYANSTELADYLVAKGIPFREAHHIVGVAVVGAIEKGC
ALEELSLAELKAFSEVIEDDVYEILTIESCLAKRCALGGVAPEQVAYAVEQAGKRLQERDNAGVKVRPARLTDLDALEGM
VAYWAGLGENLPRNRNELVRDIGSFAVAEHHGEVTGCASLYVYDSGLAEIRSLGVEAGWQSQGQGKAIVQHLVEKAREMA
IKKVFVLTRVPEFFMKQDFIPTSRSLLPEKVLKDCDQCPRQHACDEVALEVNLQEQVIIKSSVA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00324 YP_008207789.1 Argininosuccinate lyase Not tested AbaR25 Protein 8e-70 46
BJAB0868_00328 YP_008211654.1 Argininosuccinate lyase Not tested AbaR26 Protein 8e-70 46