Gene Information

Name : Wbm0464 (Wbm0464)
Accession : YP_198294.1
Strain : Wolbachia endosymbiont strain TRS of Brugia malayi
Genome accession: NC_006833
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 605187 - 606464 bp
Length : 1278 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGCATGATATAGAATATATACGCCAAAATTCTGAAGAATTCGAAAAAGCAATGGAAAGTAGGGGAATGAAAGAGTTTTC
TGCAGAAGAGATACTAAAAGTTGATCACAAGAAAAGGTTGTTGACCACTAAATTGCAAGATTTAAATAGGCAACGCAACG
AAATCACAAAAAAAATAAAAGAGCTTAAAATGAGCAAGAGCCCTTGTGAGAAGCAAATAAAGTCATCAAAAAATATCACA
AATGAGATAGAAGCAATCAGCTTAAAAGAGCAAATGGAAAAGGATAAATTAGTTAATATCTTATCTAATTTACCGAATAT
CCCTGTGCAGGGTGTACCAATAGGTGCAGGCGAGAACTCTAATTTAGAGGTGAGAAGATATCGAGAAAAGAGGCAATTTG
ATTTCGTGCCAAAGTCTCATTATGAACTCGGAGAAAGGTTAGGTTTAATGGATTTCGAGCAAGCAGCAAAAATTTCTGGG
TCAAGATTTGCGATATTAAAAGGGCAGCTAGCTAAGCTTGGACGAGCACTAATAAATTTTATGCTTGAAATGCATGTTAA
TGAATTTGGCTATACTGAGGTATATCACCCAGTCTTGGTAAAAAATGAGGCTATGTATAATGTTGGTCAGCTACCGAAAT
TTTCTGATGATTCATATCTAACTACCGACGAATTAAGATTAATCCCCACAGGTGAGGTGGTTTTAACAAATTCGGTTGCT
GATAAAATAGTAGAAGAAAAGAAACTGCCTATTCGTTTTACTGCATATTCAGAATGTTTTCGTAAAGAGGCTGGTAGTGC
AGGACAAAGCACGAGAGGCATGATAAGGCAACACCAATTTGGTAAAGTAGAGTTGGTAAGTATCACAACTGAAGATCAAT
CAAATGATGAACTTGAGCGTATGACAGGTGTTGCTGAAGAGATATTAAAAAGATTAGAACTGCCATATAGAGTAATACTA
TTATGCAGCGGCGATATGGGCTTTGCTGCACAAAAGACCTATGATATAGAGGTGTGGTTACCTGAGCAAAATAGGTATAG
AGAAATATCGAGCTGTTCAAATTGTGGTAATTTTCAGGCAAGGAGGATGAACGCTAAATACTCTTTAGAAGCTAATAAAA
AGGTAAAAAAATATGTTCACACTTTAAATGGCTCGGCTTTAGCTATAGGAAGAACGATTATTGCCGTAATGGAAAATTAT
CAAAATCCTGACGGGTCGATTACAATACCAAATGTGTTGCAAAAATACATCAGTAATGGTACTGTTATAAGCAAATAA

Protein sequence :
MHDIEYIRQNSEEFEKAMESRGMKEFSAEEILKVDHKKRLLTTKLQDLNRQRNEITKKIKELKMSKSPCEKQIKSSKNIT
NEIEAISLKEQMEKDKLVNILSNLPNIPVQGVPIGAGENSNLEVRRYREKRQFDFVPKSHYELGERLGLMDFEQAAKISG
SRFAILKGQLAKLGRALINFMLEMHVNEFGYTEVYHPVLVKNEAMYNVGQLPKFSDDSYLTTDELRLIPTGEVVLTNSVA
DKIVEEKKLPIRFTAYSECFRKEAGSAGQSTRGMIRQHQFGKVELVSITTEDQSNDELERMTGVAEEILKRLELPYRVIL
LCSGDMGFAAQKTYDIEVWLPEQNRYREISSCSNCGNFQARRMNAKYSLEANKKVKKYVHTLNGSALAIGRTIIAVMENY
QNPDGSITIPNVLQKYISNGTVISK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 2e-97 48