Gene Information

Name : Wbm0181 (Wbm0181)
Accession : YP_198014.1
Strain : Wolbachia endosymbiont strain TRS of Brugia malayi
Genome accession: NC_006833
Putative virulence/resistance : Virulence
Product : ATP-binding subunit of Clp protease and DnaK/DnaJ chaperones
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 230606 - 233167 bp
Length : 2562 bp
Strand : +
Note : -

DNA sequence :
ATGGACTTAAATAAATTTACCGAAAAAGCAAAAAGCCTAATTCAAAGTGCCCAAATGAAAGCATTGGGAACTGGGCATCA
GGTTTTTATGCCTGAGCATTTACTAAAGGTGATGCTTGAGGATGAATCAGGTTTAGTTCAAGATTTAATAGGCGCTTGTG
GTGGAAATGCGCAAAGTATTTCTGACGCTGTGAATAATGCAATAAAAAAGTTTCCAATAGTCAAAGGTCCAGGAAGCAAT
AGCCTTCAACTCTCAAGAGAAGTAGCAAAAGTCTTTGAAGATTCAATTGGTATGGCTAGAAGGAACAAAGATTCATTTGT
CACCGTTGAGCGTTTACTGCAGGGATTGACTGCACAAAAAAATGATACTGTAGGTAAAATTCTGGCAGAGAACGGCATCA
CACCACAAAAATTAAATTCAGTTATTACAGAAATGAGAAAAGGTAGCAGTGCAGATTCGCCTAACAGTGAGGAAAATTTA
AACGCAGCGAAGAAATATACAAAAGATGTTACGGAGCTTGCTATGCAAGGCAAGCTTGATCCCGTGATTGGTCGTGATGA
AGAGATCAGAAGAACCATGCAAGTATCACTGAGGCGAACAAAGAATAACCCAGTGCTGATAGGTGAACCTGGTGTTGGAA
AAACCGCGATAGTTGAAGGGCTTGCAAATAGAATTGTTGCAAATGACGTGCCACTTGGTTTACATGACGCAAAAGTTTTA
GCCTTAGATCTTGGTGCATTAATTGCTGGGACAAAATTTAGAGGAGAGTTCGAGGAAAGACTAAAAGCTGTTATCAATGA
GCTTGCAAAAGCAGAGGGAAAAATTATCTTGTTCATAGATGAGCTTCATACTTTAGTTGGAGCAGGAGCAACAAGTGGTG
CAATGGATGCTTCAAATCTGTTGAAGCCTGCTCTTGCACGCGGAGAAATTCGCTGCATAGGAGCCACAACTTTAGATGAG
TATCGTGAACATATAGAAAAAGATCCTGCACTTGCAAGGCGTTTCCAACCTGTGTTTATTTCTCAACCAACTGAAACTGA
TACCGTCTCTATACTAAGAGGTTTGAAGGAAAGGTATGAAGTACATCATGGTATCAGAATCACAGATGGTGCAATAATCG
CTGCCGCAATGTTATCCAATAGGTATATAACAGATAGATTTTTACCTGATAAAGCAATTGACTTGATTGATGAGGCGGCA
AGCAGGGTGAGAATTGAAATGGATAGCAAACCTGAGATTATTGATGAACTTGAAAGAAAGATTGTACAGCTAAAAATTGA
GTCAGAAGTTCTGAAAAAAGAACGTGATGAAAATTCTAAGCAGCGCCTAAAGAAGATAAATGAGGAAATCGAAAACCTAA
ACAGTAAATTTACTGACTTAAACAGTAAATGGCAAATGGAAAAGAATAAAATAGCTAGAATACAAGAAACAGCTGAAAAA
CTAGATAATGCGAGAAAAGAGCTGGAGTTAGCTCAGCGCAGTGGAAAATTAGAAAAAGCAGGAGAACTGATGTATGGTGT
AATTCCTCATCTTGAAAATGAATTAATGAATCAGGAGAAAGTTACCGATAGCTTCTTAAAAAAAGAAGTTACTGAAGATG
ATATTGCAAATATTGTTTCAAAGTGGACAGGAATTCCAGTTGATAATATGATGCACAGTGAAAAGGAAAAACTCCTTAGC
ATGGAAAATGAGATAGGAAAAAGGGTGATAGGACAAAAGGATGCAATAGAAGCAATAAGTAATGCAGTTAGACGCTCCCG
CTCTGGTGTTCAGGATACTAATCGACCTTTTGGTTCATTCTTATTTTTGGGCCCAACCGGAGTTGGAAAAACGGAACTTG
CGAAAGCCCTTGCTGAATTTCTGTTTGATGATCAATCAGCACTTCTGCGCTTTGATATGTCAGAGTACATGGAAAAACAT
TCCGTTTCAAAGTTAATTGGTGCACCCCCAGGATATGTTGGCTATGAGCAAGGTGGAAGATTAACTGAAGCAGTAAGAAG
AAGGCCATATCAGGTAATCTTGTTTGATGAAATAGAGAAAGCGAATCCAGATATATTTAATCTATTGCTGCAGATTTTGG
ATGAAGGCAGGCTCACCGATAGCCATGGAAAATTAATTGATTTCCGTAATACTATACTAATTTTAACTTCCAACCTTGGC
GCTGAGATAATGCTTAAAGGAGTTGCTGACTTTGTAAAAAGCGAAGTGATGCAAATAGTTAAATCAGCATTTCGTCCTGA
ATTTTTAAACAGACTTGACGAAATTATTATATTCCATAGTTTAACCAAGGACGACATTTATAAAATAATAGATGTTCAAT
TCCTCTATTTACAAAAAATAATTGTTAAGCGTAAGCTAAGTATAAGTTTATCGCAGGAAGCCAAAGAACTAATAGCACAA
GCTGGCTACGATCCCGAATATGGGGTAAGACCACTAAAAAGGGTAATACAAGAATGCATTCAAAATAATCTAGCTAAGTT
AGTTTTATCGGGAGAAGTAGCAGAAGGTGATAAATTAATAGTGTACGCTTTTAATAATGAAATCTTAGTTAAAAAGGTTT
AA

Protein sequence :
MDLNKFTEKAKSLIQSAQMKALGTGHQVFMPEHLLKVMLEDESGLVQDLIGACGGNAQSISDAVNNAIKKFPIVKGPGSN
SLQLSREVAKVFEDSIGMARRNKDSFVTVERLLQGLTAQKNDTVGKILAENGITPQKLNSVITEMRKGSSADSPNSEENL
NAAKKYTKDVTELAMQGKLDPVIGRDEEIRRTMQVSLRRTKNNPVLIGEPGVGKTAIVEGLANRIVANDVPLGLHDAKVL
ALDLGALIAGTKFRGEFEERLKAVINELAKAEGKIILFIDELHTLVGAGATSGAMDASNLLKPALARGEIRCIGATTLDE
YREHIEKDPALARRFQPVFISQPTETDTVSILRGLKERYEVHHGIRITDGAIIAAAMLSNRYITDRFLPDKAIDLIDEAA
SRVRIEMDSKPEIIDELERKIVQLKIESEVLKKERDENSKQRLKKINEEIENLNSKFTDLNSKWQMEKNKIARIQETAEK
LDNARKELELAQRSGKLEKAGELMYGVIPHLENELMNQEKVTDSFLKKEVTEDDIANIVSKWTGIPVDNMMHSEKEKLLS
MENEIGKRVIGQKDAIEAISNAVRRSRSGVQDTNRPFGSFLFLGPTGVGKTELAKALAEFLFDDQSALLRFDMSEYMEKH
SVSKLIGAPPGYVGYEQGGRLTEAVRRRPYQVILFDEIEKANPDIFNLLLQILDEGRLTDSHGKLIDFRNTILILTSNLG
AEIMLKGVADFVKSEVMQIVKSAFRPEFLNRLDEIIIFHSLTKDDIYKIIDVQFLYLQKIIVKRKLSISLSQEAKELIAQ
AGYDPEYGVRPLKRVIQECIQNNLAKLVLSGEVAEGDKLIVYAFNNEILVKKV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 4e-164 42
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 7e-103 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Wbm0181 YP_198014.1 ATP-binding subunit of Clp protease and DnaK/DnaJ chaperones VFG0079 Protein 7e-158 44