Gene Information

Name : hemC (Wbm0777)
Accession : YP_198607.1
Strain : Wolbachia endosymbiont strain TRS of Brugia malayi
Genome accession: NC_006833
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : -
Position : 1026192 - 1027070 bp
Length : 879 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGTTAATCAGAATAGGTACCAGAGGAAGCAGTCTTGCAATTGCTCAAGCTTTGGAAGCAAAACAAAAGCTGTTGGACCT
TTTTTCTAGTTTATCTGTTGAGATCATTAAAATAAAAACTTCTGGTGACAAATATGCAAATGCGAACCTCGCTGAAATAG
GAGGTAAGGGATTGTTTATTAAAGAAATTGAGACTGAATTGATTAAGAGTAATATAGATATGGCAGTTCATTCGCTAAAG
GATGTTCCTGCATTTTTTTCAAAAGACTTAACAATTCCTTGTATTCTAGAGAGGTTAAGTCCATACGATACATTTATTTC
TAATAAGTATAAGAGCCTTAAGTCTTTGCCACAGCAGGCCATAATTGCAACTTCCTCAATAAGAAGAAAAGTCCAGTTGC
TAAATTTTAGACCAGATTTAAATATAGTACCACTGCGTGGAAATGTGACAACTAGACTGCAGAATCAAAGCTTTGATGGA
ATAATTCTAGCTGAAGCAGGATTAATAAGATTAAAAAAAGATTACTTGATCACAGAGGTACTGTCACCGAAAACTATGTT
AAGTGCAGTGGGACAGGGAGCAATTTGCATTCAATGTAGAAAAAATGATATAAAAATTATCGATCTTTTAGAGAAAATTA
ATAATAATAAGTCTTTTATAAGGGTGAAATCAGAACGCAGCTTTATGAAGACAGTAAATGGTTCATGCTTTACACCACTT
GCGGCTCTGGCAAAATATGTGAGTGAAAACGTGCTACATCTTTATTGTATGTTAGCAGACAAGAAAAATATATATTTTAC
TGAGCGCACTTCGTTTGTAGAAGATGCAGAAAAAATGGGTATGGATGCAGGATTAGAATTGAAATCAAAATGCCTATAA

Protein sequence :
MLIRIGTRGSSLAIAQALEAKQKLLDLFSSLSVEIIKIKTSGDKYANANLAEIGGKGLFIKEIETELIKSNIDMAVHSLK
DVPAFFSKDLTIPCILERLSPYDTFISNKYKSLKSLPQQAIIATSSIRRKVQLLNFRPDLNIVPLRGNVTTRLQNQSFDG
IILAEAGLIRLKKDYLITEVLSPKTMLSAVGQGAICIQCRKNDIKIIDLLEKINNNKSFIRVKSERSFMKTVNGSCFTPL
AALAKYVSENVLHLYCMLADKKNIYFTERTSFVEDAEKMGMDAGLELKSKCL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 6e-44 44
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 6e-44 44