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Name : guaA (ERWE_CDS_00680) Accession : YP_196944.1 Strain : Ehrlichia ruminantium Welgevonden Genome accession: NC_006832 Putative virulence/resistance : Unknown Product : GMP synthase Function : - COG functional category : F : Nucleotide transport and metabolism COG ID : COG0519 EC number : 6.3.5.2 Position : 105291 - 106877 bp Length : 1587 bp Strand : + Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway DNA sequence : ATGTCAAAGGTAGCTATTATTGATTTTGGGTCGCAATTTACACAATTGCTTGCTAGAAGAATAAGGGACTTAAATATTTA TTCTGAGATATTTCTACCTAATGTGGCATTTGATCTTATTAAAGGTGTTGATGCATTTATTCTGTCTGGTGGGCCTAGGT CAGTACCTAATTCAGATGGAATTCCTAAAATTGTACATGATATTCTTCAGTTTAATGAAAAGACGTCTATTCCAGTATTA GGTATATGCTATGGATTACAGATTCTCAGTAACTATTTTGAATCTGATGTTGTATCTAATTGTAATAAGGAATTTGGAAA AACCATTCTCAATATAATAAAAAATTCAAAGATAATAGAAAATATTTGGGAATCAGGGGACCAAGCTTGTGTGTGGATGA GTCATGCAGATAGTGTTTATAATATACCACGTGGTTTTGAGGTTATTGCATATAGTGTATTGAATAATTCCATTGCTATG GTAGCGAATGAACAGCGTAGGATTTATGGTATGCAATTTCATCCTGAGGTCTATCATACTCCAGATGGTATAAATTTACT TGCGAACTTTCTGGATATTGCAGGTTGCCAAAAGGATTGGACTGTAACATCTTTTATAGACGATCAGCAAGATGCTATTA AGAAACAAATTGGAAATAAAAAAGTAATAGCAGCACTTAGTGGAGGTGTTGATTCAAGTGTGGCTGCAGCGTTGACGTAT AAGGCGATAGGTGACCAACTTCATTGTGTATTTATTGACAATGGGTTATTGCGTTATAATGAAGTGGAAAAAGTAAAGCA GCTATTTATTAATGAGCTAAAAATTCCTGTAACAATTGTTGATAAATCAGCAGTGTTTCTAAATAGGTTGAAATCTATAA CTGATCCAGAACGGAAGCGTAAAATAATTGGGGAGACTTTTATTGAAATATTTGAAGAAGAGGCTAATAAGCTTGAAGGA GTAGAGTTTTTAATGCAGGGGACTATATATCCTGATGTTGTGGAATCTGGAGGTAGTGGTTCTATTGCGAAAGAAAGTGT GGTTATTAAGTCTCATCACAATGTTGGTGGCTTACCTAAAACCATGAAATTTAAGCTTGTTGAGCCATTAAAGTACTTAT TTAAAGATGAGGTAAGAATATTAGGTAGGAATCTTGGTATCTCAACTGAAATATTAATGCGTCATCCATTTCCTGGACCA GGTTTAGCAGTTAGGATAATAGGTGAAATTACTGAAGAGAAAGTAAAAATGTTACAAGCTGCTGATGATATATATATTAA TCTAATCAAAAAATACGAGTTATATGATGTTATGTGGCAAGCATTTGTAGTATTGTTGCCAGTGAAAACAGTAGGTGTGA TGGGTGACAGAAGGACATATGGTCATGCTTGTGTTTTAAGAGCAGTAAATTCACATGATGGTATGACAGCAGAAAGTTTC CCATTCTGTATGGATGAGGAAACTCAATGGAAATTTTTTAAATGTATACAGGAAGCTAGTAATGCTATCATTAATAGTGT TAATGGAATTAATAGAGTAGCGTATGATATTACATCTAAACCTCCTGCTACAATTGAATGGGAGTAA Protein sequence : MSKVAIIDFGSQFTQLLARRIRDLNIYSEIFLPNVAFDLIKGVDAFILSGGPRSVPNSDGIPKIVHDILQFNEKTSIPVL GICYGLQILSNYFESDVVSNCNKEFGKTILNIIKNSKIIENIWESGDQACVWMSHADSVYNIPRGFEVIAYSVLNNSIAM VANEQRRIYGMQFHPEVYHTPDGINLLANFLDIAGCQKDWTVTSFIDDQQDAIKKQIGNKKVIAALSGGVDSSVAAALTY KAIGDQLHCVFIDNGLLRYNEVEKVKQLFINELKIPVTIVDKSAVFLNRLKSITDPERKRKIIGETFIEIFEEEANKLEG VEFLMQGTIYPDVVESGGSGSIAKESVVIKSHHNVGGLPKTMKFKLVEPLKYLFKDEVRILGRNLGISTEILMRHPFPGP GLAVRIIGEITEEKVKMLQAADDIYINLIKKYELYDVMWQAFVVLLPVKTVGVMGDRRTYGHACVLRAVNSHDGMTAESF PFCMDEETQWKFFKCIQEASNAIINSVNGINRVAYDITSKPPATIEWE |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| SAPIG0468 | YP_005733278.1 | GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) | Not tested | SAPI-S0385 | Protein | 5e-102 | 46 |
| guaA | YP_001331415.1 | GMP synthase | Not tested | vSa¥á | Protein | 4e-102 | 46 |
| SAMSHR1132_03620 | YP_005324884.1 | GMP synthase | Not tested | vSa¥á | Protein | 4e-102 | 46 |
| guaA | NP_938969.1 | GMP synthase | Not tested | Not named | Protein | 6e-97 | 44 |
