Gene Information

Name : serS (ERWE_CDS_04760)
Accession : YP_197352.1
Strain : Ehrlichia ruminantium Welgevonden
Genome accession: NC_006832
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 759470 - 760753 bp
Length : 1284 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGCATGATATAGATTTTATAAAAAATAATCCAGAACTATTTGATGAAGCAATGCAAAATAGAAATTTTGGAAAAATCGC
CCACAAAATTATAGAATTATCTGCCAATAAAAAACACACACTAACACAATTGTACTCTTTACAAAAAGAACGAAACAATA
TAACACAAGAAATTGAAAAATTAAAAAAAGACAATATCCAATGTGATACACAAATAGAACTTTCAAAAGAAATAACAAAA
AAAATAAATCATATTAACAATATGATAAAGACAGATTCTGAATTAATTGATTTACTTAATATATTGCCAAATATACCTGA
TAAAAAGGTACCTATTGGTAAAGACGAAAATGACAATATTGAAATCAGAAGATATGGAAAAAAAGTAGATTTCAAATTTC
CACCAAAAACTCACTATGAATTAGGTGAAAACTTAAACTTAATGGATTTTAAACAAGCTGCAAAACTTTCTGGATCAAGG
TTCGTAATACTAAAAAGTCAGCTAGCACAATTAGATCGTGCTTTAGCAAATTTTATGTTAGATGTTCACACCCAAGAATT
TGGATATTCAGAAATCTCTCATCCTGTATTAGTACATGAATCTGCTATGTACGGAGTTGGACAATTACCTAAATTCGCTG
ATGATTCTTTTAAAACAACAGATAACTTTAGGCTTATTCCTACAAGTGAAGTAGCACTAACTAATTTAGTATCAAATACA
AACACTAATGCAAATGAACTACCAATAAGGTTAACTGCATGTTCTCAATGTTTCAGATCAGAAGCAGGAAGTGCTGGTAA
GGATGTACGTGGTATGATGAGACAACATCAATTCAACAAAGTAGAATTAGTAAGTATTGTTACTGAAGAACAATCAGAAT
TGGAATTAGAAAGAATGACACAAGTTGCTGAAGAAATTTTAAAAAAATTGGAACTACCATATAGAGTAATGATGCTATGT
ACAGGAGATTTAGGTTTTTCAGCAAGTATAACATATGATATTGAAGTATGGATACCAAGTCAAAATCAATATAGAGAGAT
TTCAAGTTGCTCAAATTGTAAAGCTTTTCAAGCACGGAGAATGAATGCTAAATATCATACAATAAGCAATGGTAATAAAG
TAAATAAATTTGTACATACTTTAAATGGCTCTGCGTTAGCAATAGGAAGAACTATAATTGCAATTTTAGAAAATTATCAA
AATCAAGATGGCTCTATAACTATACCACATGTACTGAGAAAATATATGAATAACCAGGATATAATAAAAAACAATAATTA
TTAG

Protein sequence :
MHDIDFIKNNPELFDEAMQNRNFGKIAHKIIELSANKKHTLTQLYSLQKERNNITQEIEKLKKDNIQCDTQIELSKEITK
KINHINNMIKTDSELIDLLNILPNIPDKKVPIGKDENDNIEIRRYGKKVDFKFPPKTHYELGENLNLMDFKQAAKLSGSR
FVILKSQLAQLDRALANFMLDVHTQEFGYSEISHPVLVHESAMYGVGQLPKFADDSFKTTDNFRLIPTSEVALTNLVSNT
NTNANELPIRLTACSQCFRSEAGSAGKDVRGMMRQHQFNKVELVSIVTEEQSELELERMTQVAEEILKKLELPYRVMMLC
TGDLGFSASITYDIEVWIPSQNQYREISSCSNCKAFQARRMNAKYHTISNGNKVNKFVHTLNGSALAIGRTIIAILENYQ
NQDGSITIPHVLRKYMNNQDIIKNNNY

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 6e-91 47