Gene Information

Name : hemC (ERGA_CDS_03750)
Accession : YP_196301.1
Strain : Ehrlichia ruminantium Gardel
Genome accession: NC_006831
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : -
Position : 621282 - 622181 bp
Length : 900 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGAATAGTATGAATGTATATCTTGGAACAAGAGGAAGTATTTTAGCTATTGCACAAGCAATGAAAGTTAAGAAGTTATT
GTATAATTATTTTCCTGATATTAATGTTCAGATTGTTCATATTGTAACTTCTGGAGATATTAATGATAAAATTTCTCTGA
GTGAGATAGGTGGAAAGGGATTATTTTTAAAAGAGTTAGAAGAAGCATTATTAACTGGTACTATAGATTTAGCTGTGCAT
TCAATGAAAGATGTACCAGCTTTTTATTGTGATAGTTTAGTTATCCCGTGTATACTGAAACGTAGTAGTCCTTATGATGT
ATTTATTTCCTCTAAATATCAAAGTTTAAGGTCATTACCTGATAATGCAGTTATAGGTACATCGTCTATTAGAAGAAAAG
TACAATTAATGAGATTGCTTTCTAGTGTACAAGTTGTTCCTATTAGAGGTAATGTAGATACTAGGATATTGAAATTGGAA
GCAGGGCAATATGATGGAATAATATTGGCTAAAGCTGGTTTAATGCGAATAAATAAAACTCATGTGATAAAAGAAGTATT
AGATCCTCAAGTGATGCTAAGTGCAGTAGGACAAGGAGCTATTGGTATTCAATGTCGAGCTAATGATTACAAGATGATAG
ATATGATAAAAATTTTAAATTGTAAAAAATCCTATATTAGTGTTGCAGCTGAAAGAAGTTTTATGAAGACTGTTAATGGT
TCATGTGATACACCATTAGCTGCACTTGCTAAATATGTTAATTCTGATACTTTGTACATGTCATGTATGCTTTCAAATGA
AGAAAAGACAGTATTTTCAGATTGTTACTTTAATGAATGTGATGCGGAAATATCAGGTATTAATATGGGAAATGACTTAA
TGGATCAGTTAAATAACTAA

Protein sequence :
MNSMNVYLGTRGSILAIAQAMKVKKLLYNYFPDINVQIVHIVTSGDINDKISLSEIGGKGLFLKELEEALLTGTIDLAVH
SMKDVPAFYCDSLVIPCILKRSSPYDVFISSKYQSLRSLPDNAVIGTSSIRRKVQLMRLLSSVQVVPIRGNVDTRILKLE
AGQYDGIILAKAGLMRINKTHVIKEVLDPQVMLSAVGQGAIGIQCRANDYKMIDMIKILNCKKSYISVAAERSFMKTVNG
SCDTPLAALAKYVNSDTLYMSCMLSNEEKTVFSDCYFNECDAEISGINMGNDLMDQLNN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 3e-47 41
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 3e-47 41