Gene Information

Name : thiC (ERGA_CDS_02970)
Accession : YP_196223.1
Strain : Ehrlichia ruminantium Gardel
Genome accession: NC_006831
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 495756 - 497423 bp
Length : 1668 bp
Strand : -
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGAAAATTGACCTTAATACTATATTCCCATCTTCATGTAAAGAATACATACCAGGTAAAATCTATAAAAATATTAAAAT
AGGTATGCGCAAAGTCTCTTTCAACAATGATACTGAATCAATCTTAATATATGATACCGGAGGACCACATTCTGATCAAG
ATATACAAACCAATATAAACAATGGTATTAAAAAATTACGGGTTAATTGGATAACAGATAGGCAAGATGTAGAATATTAT
GATAGACATACAATCAATACAAATTCCAGTACAGCATTTCCTTTACAAAATAACAAAGCTTTAAAATCCAAAAATGATAA
ACCTGTAACTCAGATGTTTTACGCAAAAAATAATATTATTACTCCAGAAATGGAATATGTTGCAATACGAGAAAACTCTT
TAATACAAAAACTTCTATCACACACACCAAATACCATAATTCCAGAAATAACTCCAGAACTTGTGAGACAAGAAGTAGCT
GCTGGTCGAGCAATTATTCCTGCAAATATTAATCATCCAGAATCAGAACCTATGATTATTGGTAAGAACTTCCTAGTAAA
AATCAATGCCAATATTGGAAACTCAGCAGTAAGTTCAGACATAAATAATGAAGTATATAAAATGATATATGCAATCATAT
ATGGTGCAGATACAGTAATGGATTTATCAACAGGAAGTCATATACATAATACTAGAGAATGGATTATTAGGAACAGCCCT
GTACCAATAGGTACAGTACCTATATACCAAGCATTGAATAAAGTAAATGGAATAGTAGGAGAACTTAATTTTAATATTTT
TAAAGAAACACTAATTGAACAAGCAGAACAAGGAGTGGATTATTTTACTATACATGCTGGTGTATTAAAAAAATACATTC
AATACACAACCAACCGGCTAACTGGCATTGTATCTAGAGGTGGAGCTATTATTGCACAATGGTGTTCTATACATAATAAA
GAGAACTTTCTCTATACAAATTTTGAGGAAATATGTGATATAATGAAAAGTTACGATATTGCTTTCTCTTTAGGAGATGG
TCTAAGACCAGGTTCTATAGCGGATGCAAACGATAAAGCACAGTTTTTAGAATTAAAGACACTAGGAGAACTTACAGATA
TTGCATGGAAACATGATTGTCAAGTTATGATAGAAGGTCCAGGACATGTACCAATGCATTTAATAAAAGAAAATGTAGAA
AAACAGATGTACTTTTGTAAAGAAGCCCCATTTTATACTTTAGGACCACTCACTACAGACATTGCTCCTGGATATGATCA
CATAACTAGTGCCATAGGTGCAGCAATGATAGGATGGTATGGTACTTCTATGTTATGTTATGTCACACCAAAAGAACACC
TTGGATTACCAAATCTCAATGATGTAAAAAATGGAGTAATTACATATAAAATCGCAGCACATGCTGCTGATCTAGCAAAA
GGTAATCCTTCCGCTTATATAAGAGATTATGCATTAAGTTATGCAAGATTTAATTTTAGATGGTACGATCAATTCAACTT
ATCACTTGATCCAGAAACAGCAAAATCTTTTCACGATGAATCTCTACCTTCTGAACATGCAAAATCTGCACATTTTTGTT
CAATGTGCGGACCAAAATTTTGCTCAATGAAATTAACACATCAACTACAACTTAACTCTACTGAATAA

Protein sequence :
MKIDLNTIFPSSCKEYIPGKIYKNIKIGMRKVSFNNDTESILIYDTGGPHSDQDIQTNINNGIKKLRVNWITDRQDVEYY
DRHTINTNSSTAFPLQNNKALKSKNDKPVTQMFYAKNNIITPEMEYVAIRENSLIQKLLSHTPNTIIPEITPELVRQEVA
AGRAIIPANINHPESEPMIIGKNFLVKINANIGNSAVSSDINNEVYKMIYAIIYGADTVMDLSTGSHIHNTREWIIRNSP
VPIGTVPIYQALNKVNGIVGELNFNIFKETLIEQAEQGVDYFTIHAGVLKKYIQYTTNRLTGIVSRGGAIIAQWCSIHNK
ENFLYTNFEEICDIMKSYDIAFSLGDGLRPGSIADANDKAQFLELKTLGELTDIAWKHDCQVMIEGPGHVPMHLIKENVE
KQMYFCKEAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWYGTSMLCYVTPKEHLGLPNLNDVKNGVITYKIAAHAADLAK
GNPSAYIRDYALSYARFNFRWYDQFNLSLDPETAKSFHDESLPSEHAKSAHFCSMCGPKFCSMKLTHQLQLNSTE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 7e-179 65
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 7e-179 65
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 3e-166 59