Gene Information

Name : LBA0746 (LBA0746)
Accession : YP_193645.1
Strain : Lactobacillus acidophilus NCFM
Genome accession: NC_006814
Putative virulence/resistance : Virulence
Product : response regulator
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 732616 - 733338 bp
Length : 723 bp
Strand : +
Note : COG0745 Response regulators conserved isting of a CheY-like receiver domain and a winged-helix DNA-binding domain

DNA sequence : 
ATGAGTTTAAATATATTAATGGTTGAAGATGACAACTCCGTTGCTGAAATGATGGGGATGTTTTTCAAAAAAGAAGGTTG
GCAACAAGATATTGCTGTTGACGGTGTCGAAGCCGTCGACATGTTTAGAAAAAATGCAGATAAGTATGATTTAATTACTT
TGGATTTGAATTTACCTAAAAAAGACGGTATTCAAGTTGCCAAAGAAGTGAGAGCAATTTCACCTACTGTACCAATTATT
ATGCTTACTGCTAGGGGAAGTGAATCAGATCAAGTACTAGGTCTTGGTATTGGAGCTGATGAATATGTCACTAAACCTTT
TAGTCCAATTGCTTTAATTGCTAGAATCAAGGCACTTCATCGTAGAGTTATGATGGAAGAAGAGCCGGATACTGCTAAAG
AAGATAAGCAAGATTATGAAATTACCACAAAACACCTAAAAATTTCTAAAAATAGACGAGAAGTATTGTTTGACAAGCAA
CCTGTAACTAATTTAACTCCAAAGGAATTTGACTTGCTTTATACGATGGCTCAAAAGCCTAAGCAAGTCTTTTCTCGTGA
ACAATTATTAGAGCTGGTTTGGGGATATGAATACTACGGAGAAGAAAGAACAGTAGATGCTCATATTAAGAAACTGCGCC
AAAAATTAGAGAAAGTTGGAGCTAAAGTTATCCAAACCGTTTGGGGAGTTGGATATAAGTTTGATGATTTGCAGGTAGAA
TAA

Protein sequence : 
MSLNILMVEDDNSVAEMMGMFFKKEGWQQDIAVDGVEAVDMFRKNADKYDLITLDLNLPKKDGIQVAKEVRAISPTVPII
MLTARGSESDQVLGLGIGADEYVTKPFSPIALIARIKALHRRVMMEEEPDTAKEDKQDYEITTKHLKISKNRREVLFDKQ
PVTNLTPKEFDLLYTMAQKPKQVFSREQLLELVWGYEYYGEERTVDAHIKKLRQKLEKVGAKVIQTVWGVGYKFDDLQVE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD42044.1 hypothetical protein Not tested PAI II 536 Protein 5e-35 42
c3565 NP_755440.1 response regulator Not tested PAI I CFT073 Protein 6e-35 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
LBA0746 YP_193645.1 response regulator CP001918.1.gene5135. Protein 1e-24 43
LBA0746 YP_193645.1 response regulator NC_002952.2859905.p0 Protein 1e-39 42
LBA0746 YP_193645.1 response regulator NC_013450.8614421.p0 Protein 7e-40 42
LBA0746 YP_193645.1 response regulator NC_007793.3914279.p0 Protein 7e-40 42
LBA0746 YP_193645.1 response regulator NC_007622.3794472.p0 Protein 9e-40 42
LBA0746 YP_193645.1 response regulator NC_002745.1124361.p0 Protein 7e-40 42
LBA0746 YP_193645.1 response regulator NC_009782.5559369.p0 Protein 7e-40 42
LBA0746 YP_193645.1 response regulator NC_002951.3237708.p0 Protein 7e-40 42
LBA0746 YP_193645.1 response regulator NC_003923.1003749.p0 Protein 6e-40 42
LBA0746 YP_193645.1 response regulator NC_002758.1121668.p0 Protein 7e-40 42
LBA0746 YP_193645.1 response regulator NC_009641.5332272.p0 Protein 7e-40 42
LBA0746 YP_193645.1 response regulator HE999704.1.gene2815. Protein 3e-38 42
LBA0746 YP_193645.1 response regulator AF155139.2.orf0.gene Protein 2e-41 41
LBA0746 YP_193645.1 response regulator FJ349556.1.orf0.gene Protein 3e-39 41
LBA0746 YP_193645.1 response regulator AE000516.2.gene3505. Protein 2e-34 41
LBA0746 YP_193645.1 response regulator NC_012469.1.7685629. Protein 3e-37 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
LBA0746 YP_193645.1 response regulator VFG1563 Protein 3e-35 42
LBA0746 YP_193645.1 response regulator VFG1702 Protein 3e-35 42