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Name : secA (LBA0673) Accession : YP_193580.1 Strain : Lactobacillus acidophilus NCFM Genome accession: NC_006814 Putative virulence/resistance : Unknown Product : preprotein translocase subunit SecA Function : - COG functional category : U : Intracellular trafficking, secretion and vesicular transport COG ID : COG0653 EC number : - Position : 659172 - 661571 bp Length : 2400 bp Strand : + Note : functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis ap DNA sequence : ATGGCAAATATTTTAAAGAAACTATATAACACTGATAAAAGAGAACTTAAAAAATTTGAAAAATATGCAACTAAAGTAGA AGAACACGCTGATGAAATGAGTAAATTGTCAGATGAACAATTGCAAGCTAAGACACCAGAATTTCGTGAGCGCATTAAAA ATGGTGAAAGCTTAGATGATCTTTTGCCAGAAGCATTTGCAGTTGCTCGTGAAGGTGCAAAGCGTGTATTAGGGCTTTAC CCATTCCACGTTCAAATTTTGGGTGGTATTGCATTACACTTTGGTAATATCGCTGAAATGATGACTGGTGAAGGTAAGAC TTTAACCGCAACAATGCCCGTTTATTTAAACGCCTTGGAAGGCAAGGGTGTGCACGTTGTTACTGTTAATGAATACCTTT CTAGTCGTGACGAAGAAGAAATGGGACAGCTTTATAGATGGCTCGGCTTAACTGTTGGTTTGAACATTAACTCAATGTCA CCAGATGAAAAGCGTGAAGCATATAACTGTGACGTTACTTATTCAACTAACTCAGAACTGGGTTTTGACTATTTACGTGA CAACATGGTTGTCTATAAAGAGCAAATGGTTCAACGTCCATTGAACTATGCTATTATCGATGAAGTTGACTCCATCTTAA TTGATGAAGCTAGAACTCCTTTGATTATTTCTGGTGAAGCTGAACAAGCAAATAGTGATTATATTCGTGCTGATCGTTTT GTTAAGACTTTGACTGAAGATAAGAGCGATGACGATGCAGATGATGATGAAGATCACGGCGATTACAAGATTGACTGGCC AACTAAGACTATTTCACTTACCAGAACTGGTATTGAAAAGGCTTGTGAACACTTCGGCTTAAAGAACTTATACGATGTTG AAAACCAAAAATTGGTTCACCATATTGATCAAGCACTTCGTGCAAATTATATTATGTTGAAAGATATTGATTATGTCGTT CAAGATGGTGAAGTTTTAATCGTTGATTCCTTTACTGGTCGTGTAATGGAAGGTCGTCGTTATTCAGATGGTTTACACCA GGCTATTGAAGCTAAGGAAGGCGTCAAGATTCAAGAAGAATCTAGAACGCAAGCTACTATTACGTATCAGAACTTCTTTA GAATGTACAAGAAATTATCAGGTATGACTGGTACCGGTAAAACTGAAGAAGAAGAATTCCGTGAAATTTACAACATGCAA GTAATTACGATTCCAACCAATCGTCCAATTGCTAGAAAAGATATGCCAGATATTTTGTATCCAACTTTAGATTCAAAATT CCATGCTGTAATTGAAGAAATTAAGAAGCGTCATGCAAAGGGACAACCTGTTTTGGTTGGTACTGTTGCTATCGAAAGTT CAGAACGACTTAGTCATTTGCTTGATGAAGCAAATATTCCACACGCTGTGTTAAATGCTAAGAATCACGCTAAAGAAGCA CAAATTATTATGAATGCAGGTCAGCGTGGAGCAGTAACTATTGCGACTAATATGGCTGGACGTGGTACTGATATTAAACT AGGGCCTGGAGTTAAAGAACTTGGTGGTTTAGCAGTTATTGGTACTGAACGTCATGAATCACGTCGTATTGATAACCAGC TTCGTGGTCGTTCTGGTCGTCAGGGAGATCCAGGTTACACTAGATTTTACCTATCACTTGAAGATGACTTGATGAAGCGT TTCGGTGGAGACCGCGTAAAAGACTTCTTAGATCGTCTTTCAGATAATGATGATGAAAAGGTAATTGAAAGTCGTTTGAT TACCCGTCAAGTTGAATCTGCTCAAAAGCGTGTTGAAGGTAATAACTACGATACTCGTAAGCAAACTTTGCAATATGATG ATGTTATGCGTATCCAACGTGAAATTATCTATGGTGAAAGAATGCAAGTGATCGAAGCAGATAAGTCATTGAAGAACGTT TTGATTCCAATGATTCACCGTACTATTAATAGTCAAGTGGATATGTTTACTCAAGGCGATAGAAGTCAATGGCGTTTAGA TTCATTACGGGATTTCATTTCTTCAAGTCTAGCTTCAGAACAAGTCACTGATTCAATTGACTTTAAGACAATTAGTGTTG AAGATTTGAAGAAGAAATTATATGACATCGTTGAAAAGAACTTTGAAGACAAAGAGAAAGCTTTAGGCGATCCAAGTCAA ATGCTTGAGTTTGAAAAAGTTGTTATTTTGCGTGTTGTTGATGACCGCTGGACTGATCATATTGATGCAATGGATCAATT ACGTCAATCAATCGGACTTCGTGGGTATGGACAACTTAATCCACTTGTCGAATATCAAGATTCTGGTTATAGAATGTTTG AAGAAATGATTTCAAATATTGAATTTGATGTAACTCGTTTGTTCATGAAGGCTGAAATTAGACAAAATCTTAGTCGTTAA Protein sequence : MANILKKLYNTDKRELKKFEKYATKVEEHADEMSKLSDEQLQAKTPEFRERIKNGESLDDLLPEAFAVAREGAKRVLGLY PFHVQILGGIALHFGNIAEMMTGEGKTLTATMPVYLNALEGKGVHVVTVNEYLSSRDEEEMGQLYRWLGLTVGLNINSMS PDEKREAYNCDVTYSTNSELGFDYLRDNMVVYKEQMVQRPLNYAIIDEVDSILIDEARTPLIISGEAEQANSDYIRADRF VKTLTEDKSDDDADDDEDHGDYKIDWPTKTISLTRTGIEKACEHFGLKNLYDVENQKLVHHIDQALRANYIMLKDIDYVV QDGEVLIVDSFTGRVMEGRRYSDGLHQAIEAKEGVKIQEESRTQATITYQNFFRMYKKLSGMTGTGKTEEEEFREIYNMQ VITIPTNRPIARKDMPDILYPTLDSKFHAVIEEIKKRHAKGQPVLVGTVAIESSERLSHLLDEANIPHAVLNAKNHAKEA QIIMNAGQRGAVTIATNMAGRGTDIKLGPGVKELGGLAVIGTERHESRRIDNQLRGRSGRQGDPGYTRFYLSLEDDLMKR FGGDRVKDFLDRLSDNDDEKVIESRLITRQVESAQKRVEGNNYDTRKQTLQYDDVMRIQREIIYGERMQVIEADKSLKNV LIPMIHRTINSQVDMFTQGDRSQWRLDSLRDFISSSLASEQVTDSIDFKTISVEDLKKKLYDIVEKNFEDKEKALGDPSQ MLEFEKVVILRVVDDRWTDHIDAMDQLRQSIGLRGYGQLNPLVEYQDSGYRMFEEMISNIEFDVTRLFMKAEIRQNLSR |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| secA2 | YP_006310687.1 | preprotein translocase subunit SecA2 | Not tested | FWisland_3 | Protein | 6e-137 | 42 |
