Gene Information

Name : clpE (LBA1910)
Accession : YP_194739.1
Strain : Lactobacillus acidophilus NCFM
Genome accession: NC_006814
Putative virulence/resistance : Virulence
Product : ATP-dependent protease
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 1919088 - 1921217 bp
Length : 2130 bp
Strand : -
Note : ClpE

DNA sequence :
ATGGCATACTTTGATAATGATTTTGACAATTTATTTAACGAATTAAATAGCTCATTCTTTAACGATGATTTTGGAAGCAG
AAGAAGCGATAATAACGGCAATTCTGGTTCTATTCCTATGAACTACTCAAGTAACATGAGTTCTTCACCACGTACTATTC
AACAAAATCCACAACAACCAAATGAAAAGCCAATTGGTGTAGATTTAGTTGAAGAAGCTAAGAACAACAAGTTTGACCCA
GTTATTGGTCGTGATGAACAAATTGATAACGTAATTGAAATTTTATCAAGACGTAAGAAGAATAATCCTGTTTTAATTGG
ACCTGCTGGTGTTGGTAAGACTTCTATCGTAGAAGGTTTGGCTGAAAGAATTGCCGCTGGTAATGTTCCAGCTAAGATGG
CTAACATGCACATCATTTCAGTAAACATTAATGATATGGTTGCTGGCTCAAGTCTTCGTGGTAGCTTTGAAGAAAGATTA
AAGAAAGTTATCGACAAGGCTAAGAGTGACCCTAACATTGTTTTATTCATTGATGAATTACACAACATTGTTGGTGCAGG
TTCTACTGATTCTGAAAATAACAACGGTGACGCTGCTAACATTTTGAAACCAGCTCTTGCAAGCGGTGAATTAAAGTTAA
TCGGTGCTACTACTACAAGTGAATTCCAAAGAATTGAAAAGGACCCAGCTCTTTCACGTAGATTCCAAGCTGTTCAAGTT
CCAGAACCTTCAACTGATGTAGCTATCAAGATTTTGGAAGGCTTGAAGAAGAAATACGAAGACTACCACCACGTAAAATA
CACTGATGACAGTCTTAAATTAGCTGTAGAATTATCAGAAAGATACATTCAAGGTCGTTACTTACCAGATAAAGCTATCG
ATTTGATGGATGAAGCTGGTGCTAAGAAGGCTTTGCTTGTACAACCAACTGATGAAAAGAGTCTTAAGAACCAAATTAGT
GCTCTTGAAGCTAAGAAGGCAGAAGCTGCTAAGGCAGAAGACTATGACAAGGCTGCTGAAATCAAAGAAAAGATTGCTAG
CCTTGAATCACAATTAAAGAGCGTAGATAGCAAGAATACTCCAGAAGTAACTGCAAAAGATATCTACCAAATTATTGAAC
AAAAGACTAAGATTCCTATGAGTGAACTTCACGCTGATGAAGCTCAAAAGAACTTAGACTTGGCTAAGAAATTAAAGAAG
AACGTTATTGACCAAGATAGAGCAATTGACGTAATTACTGACGCTATCGCTCGTAAGCAAATCTTCAAAGACAGCGATCG
TCCTACTGGTTCATTCTTACTTACTGGTCCTACAGGTGTTGGTAAGACTGAACTTGCTAAGCAATTAGCTATTCAATTAT
TTGGTAACAAGGAACACTTAATCCGTTTGGATATGAGTGAATACCAAGATGAAATGGCAGTTAACAAGTTGATTGGTTCT
GCACCAGGTTACGTAGGCTATGGTGAAGGTGGTCAATTAACTGAAAAAGTTCGTCACCAACCATACTCATTGATTTTGTT
TGACGAAATTGAAAAGGCTAACCCACAAGTTTTCAACGCACTTCTTCAAATTATGGATGACGGTCGTTTGACTGATGCAC
AAGGTAGAACTGTATCATTCAAGGATACTATCTTAATTATGACTTCAAACGCTGGATTCTCAGACAAGTTGCTTGAAGAC
GGTAAAGTTGATCAAGACAAGTTAATCTCAGCTCTTGAAAACTACTTCAGACCTGAATTCTTAAACCGTTTGGACGCAAT
CGTACCATTCAACTCACTTACTGAACAAGACATGGGTAAGATTATCAACATTTACTTGAAGAAGATGTCACATGTACTTG
CTAAGAAGGGTGTAACTGTTGAAGTTTCAGATGAAGCTAAAGAATTCTTGGCAGAAAAAGGTTATGACAAGAAGTTCGGT
GCTCGTCCACTTAGAAGAGTTGTTGAACAAAACCTTGAAACTCCAGCTGCTAAGTTAATCTTAAGAGAACCTGACACTAA
GAAGATTGAATTCACTGCTGACGACAAGCACTTATACTTGAACGGCAAGGCAATCTTTGACATTTCTCCAAAGGTTGAAG
AAAAAGTTAAGGAAGACGAAGCTAAAGCTGAAGGCAAAAAAGAAGACTAA

Protein sequence :
MAYFDNDFDNLFNELNSSFFNDDFGSRRSDNNGNSGSIPMNYSSNMSSSPRTIQQNPQQPNEKPIGVDLVEEAKNNKFDP
VIGRDEQIDNVIEILSRRKKNNPVLIGPAGVGKTSIVEGLAERIAAGNVPAKMANMHIISVNINDMVAGSSLRGSFEERL
KKVIDKAKSDPNIVLFIDELHNIVGAGSTDSENNNGDAANILKPALASGELKLIGATTTSEFQRIEKDPALSRRFQAVQV
PEPSTDVAIKILEGLKKKYEDYHHVKYTDDSLKLAVELSERYIQGRYLPDKAIDLMDEAGAKKALLVQPTDEKSLKNQIS
ALEAKKAEAAKAEDYDKAAEIKEKIASLESQLKSVDSKNTPEVTAKDIYQIIEQKTKIPMSELHADEAQKNLDLAKKLKK
NVIDQDRAIDVITDAIARKQIFKDSDRPTGSFLLTGPTGVGKTELAKQLAIQLFGNKEHLIRLDMSEYQDEMAVNKLIGS
APGYVGYGEGGQLTEKVRHQPYSLILFDEIEKANPQVFNALLQIMDDGRLTDAQGRTVSFKDTILIMTSNAGFSDKLLED
GKVDQDKLISALENYFRPEFLNRLDAIVPFNSLTEQDMGKIINIYLKKMSHVLAKKGVTVEVSDEAKEFLAEKGYDKKFG
ARPLRRVVEQNLETPAAKLILREPDTKKIEFTADDKHLYLNGKAIFDISPKVEEKVKEDEAKAEGKKED

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 2e-127 45

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpE YP_194739.1 ATP-dependent protease VFG0080 Protein 5e-146 52
clpE YP_194739.1 ATP-dependent protease VFG0079 Protein 4e-125 45