Gene Information

Name : purA (LBA1892)
Accession : YP_194721.1
Strain : Lactobacillus acidophilus NCFM
Genome accession: NC_006814
Putative virulence/resistance : Unknown
Product : adenylosuccinate synthetase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0104
EC number : 6.3.4.4
Position : 1902006 - 1903295 bp
Length : 1290 bp
Strand : -
Note : catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis

DNA sequence :
ATGACAGCAGTTGCAGTTGTAGGGAGCCAATGGGGCGATGAAGGTAAAGGAAAGATTACTGACTTTTTAAGTAAAGATGC
CGCAATGGCAGTTCGCTCAAACGGTGGTAATAACGCAGGTCACACCATTGATATTGATGGCAAGACTTTCAAGATGCGTT
TAATTCCTTCAGGAATTTTTGCAGCTAAGGATAACACAGTTATTGGTAATGGTGTTGTAATTAACCCAGAAGTTATGTTT
AGTGAACTTGAAAATCTTGAAAAGAACGGTATTGATACTAGTGGCTTGAGAATTTCTAACCGTGCTCACATTATTATGCC
TTACGACATTAAGCAAGATGAATACCAAGAAGAAGCTAAGGGTAAAAATAAGATTGGTACTACTAAGAATGGTATTGGTC
CAACTTACATGGATAAAGCTTCAAGAATAGGTATTCGCGTTTGTGATTTACTCGAAAAAGATACTTTTGAAGAAAAGCTT
CGTACTAATCTTGAAATTAAGAACGAATTATTTACTAAGGTTTATGGTAAACCAGCTCTTAAATTTGAAGATATTTTTGA
CAAGTACTATGAATATGGTCAAAGAATGAAGAAATACGTTACTGACACTTCAGTTTTAGTAAATGACGCGCTTGACCAAA
ATAAGAAGGTTTTATTTGAAGGGGCACAAGGTATCATGCTTGATATTGATGAAGGTACTTACCCATTTGTAACTTCTTCA
AACACTATTTCAGGTGGTATTGCTTCAGGTATCGGTATTGGTGCCAACCGTTTGGATACTGTAATTGGTGTCTGCAAAGC
TTACACTACTAGAGTAGGTGCAGGTCCATTCCCAACAGAACTTCTTGATGAGACTGGTGATCGTATTCGTGAAATTGCTC
ATGAATATGGTACTGTTACTGGTCGACCACGCCGTGTGGGTTGGTTTGACTCCGTTGCTCTTCGTCACTCAAAGCGTGTT
GCTGGTATCAATGGCCTTAGCTTAAACTTGCTTGATGTATTTTCAGGTTTTGACAAGATTAAGATTTGTACTGCTTATGA
ACTTGATGGTGAAAAGATTGATTACTATCCAGCAAGTTTAAAGGAACTTTACCGTTGTAAGCCAGTTTATGAAGAACTTC
CAGCATGGGAAGAAGATATTACTCAAGTTAAGACTTGGGATGAACTTCCAGAAAATGCTAAGAAATTCTTGAACCGTATT
TCTGAATTAGTGGGTGTTCCACTAGTGACTGTTTCAGTTGGACCTGACCGTGAACAAACTATCGTATTGAAGAATCCATG
GGAAATGTAA

Protein sequence :
MTAVAVVGSQWGDEGKGKITDFLSKDAAMAVRSNGGNNAGHTIDIDGKTFKMRLIPSGIFAAKDNTVIGNGVVINPEVMF
SELENLEKNGIDTSGLRISNRAHIIMPYDIKQDEYQEEAKGKNKIGTTKNGIGPTYMDKASRIGIRVCDLLEKDTFEEKL
RTNLEIKNELFTKVYGKPALKFEDIFDKYYEYGQRMKKYVTDTSVLVNDALDQNKKVLFEGAQGIMLDIDEGTYPFVTSS
NTISGGIASGIGIGANRLDTVIGVCKAYTTRVGAGPFPTELLDETGDRIREIAHEYGTVTGRPRRVGWFDSVALRHSKRV
AGINGLSLNLLDVFSGFDKIKICTAYELDGEKIDYYPASLKELYRCKPVYEELPAWEEDITQVKTWDELPENAKKFLNRI
SELVGVPLVTVSVGPDREQTIVLKNPWEM

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
purA YP_281500.1 adenylosuccinate synthetase Not tested Not named Protein 5e-135 65