Gene Information

Name : LBA1626 (LBA1626)
Accession : YP_194470.1
Strain : Lactobacillus acidophilus NCFM
Genome accession: NC_006814
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 1634900 - 1636207 bp
Length : 1308 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGCTTGATATTAAAGTGATTCGCGAGAATCTTGATTGGTCAAAGAAAAAGTTAGCTACACGTGGCATTAAGCCAGAAGA
ATTGGACGAATTAGTTGAAATTGATACTAAACGTCGTAAAGATTTGACTATGAGTGAACAATTGAAGGCTAAGCGTAACG
ATGTTTCTAAGCAAATTGCTGAAAAAAAGCGTAATAAAGAAGACGCAAGCGATGCAATTGCTGAAATGCGTGAAGTAGGT
AAAGAAATTAAGAAATTGGATAAAGAAGTTGACGAATTAACTGAAAAGCAAAATTACATTTTGCTTAGATTGCCTAACTT
CCCAGCAGATTCAGATCCAATTGGTCCAGATGACAGCTACAATGAAGAAGTTCGTAAGTGGGAAGAACCAACTAAGTTTG
ACTTCAAGCCAAAGGCTCACTGGGATCTTGGTACTGATCTTGGTATCTTAGACTGGGATCGTGCTTCTAAAGTTTCAGGT
GCACGTTTTGTTTACTACATTGGTGCAGGTGCCCTTTTGGAACGTGCTGTATTTAACTTCTTCCTTGATGAAAACACTAA
GGATGGTTATACAGAAATTATTCCACCATATTTGGTAAATGATGCTTCAATGCAAGGAACTGGTCAATTCCCTAAGTTCC
ATGAAGACGTTTATACTATTGTAGATAACGATGATCCAGATAAGCCTCGTGATTTGACTTTAATTCCAACTGCTGAAGTT
CCTTTGGTAAACTACTTTAGAAATGAAATTATTCACGAAAACAAATTACCAATTAATGTAACTGCTATGTCACCAGCATT
CAGAAGTGAAGCAGGTTCTGCTGGTCGTGATACTCGTGGTTTAATTAGAATGCACGAATTTCGTAAGGTAGAAATGGTTA
AGATTTGTAAACCTGATGAATCATGGGATGAACTTGAAAAGTTAACTCATAATGCAGAACATTTATTGCAAAAGCTTGGT
TTACCATATCACGTAGTTGCTTTGTCAACTGGGGATGCAAGTTTCACTAGTGCTAAGACATACGACCTTGAAGTTTGGAT
GCCAGCACAAGACAAGTACCGTGAAATCTCAAGTTGTTCAAACTGTACCGACTTCCAAGCTCGTCGTGCACAAATTCGTT
ACCGTGATGAAGATGGTAAACTTCACTTAGCACATACTTTGAACGGTTCAGGTTTAGCAGTAGGCCGTTGTGTAGCTGCA
ATTTTGGAAAACTACCAAAATGAAGATGGCTCAGTAACTGTTCCGGATGTTCTTGTACCTTACATGAATGGTATGAAGAA
GATTACTAAGGAATCTGGTTTGATTTAG

Protein sequence :
MLDIKVIRENLDWSKKKLATRGIKPEELDELVEIDTKRRKDLTMSEQLKAKRNDVSKQIAEKKRNKEDASDAIAEMREVG
KEIKKLDKEVDELTEKQNYILLRLPNFPADSDPIGPDDSYNEEVRKWEEPTKFDFKPKAHWDLGTDLGILDWDRASKVSG
ARFVYYIGAGALLERAVFNFFLDENTKDGYTEIIPPYLVNDASMQGTGQFPKFHEDVYTIVDNDDPDKPRDLTLIPTAEV
PLVNYFRNEIIHENKLPINVTAMSPAFRSEAGSAGRDTRGLIRMHEFRKVEMVKICKPDESWDELEKLTHNAEHLLQKLG
LPYHVVALSTGDASFTSAKTYDLEVWMPAQDKYREISSCSNCTDFQARRAQIRYRDEDGKLHLAHTLNGSGLAVGRCVAA
ILENYQNEDGSVTVPDVLVPYMNGMKKITKESGLI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 1e-130 65