Gene Information

Name : leuS (LBA1617)
Accession : YP_194462.1
Strain : Lactobacillus acidophilus NCFM
Genome accession: NC_006814
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 1618587 - 1621001 bp
Length : 2415 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
TTGTATAACCACAAAGTAGTTGAAAAGAAATGGCAAGATTATTGGGCAAAACACGATACCTTTAAGACAGGTACTGATTC
CAATAAGAAGAATTATTACGCATTAGATATGTTTCCGTTCCCATCTGGTAAAGGACTTCATGTGGGTCACCCAGAGGGAT
ATACTGCAACTGATATTGTGTCTAGAATGAAGCGTGCTCAAGGTTACAATGTACTTCACCCAATGGGTTGGGATGCTTTT
GGTTTACCAACTGAACAATACGCTTTAAAGACTGGTGAAGATCCTGAAGTTGTTACTAAAAATAATATTGCTAACTTCAA
GCGTCAATTAAATAAGTTAGGCTTCTCATATGATTGGGATCGTGAAGTTACTACTTCAGATCCTAATTACTACAAGTGGA
CTCAATGGGTCTTTGAACAAATGTACAAGAAGGGCTTAGCATATGAAGCAGAAGTGCCAGTTAACTGGTCTCCAGATTTA
GGTACTGTTGTCGCAAACGAAGAAATTGTGGATGGTAAGACTGAACGTGGTGGGTACCCAGTATATCGTCGTAACATGCG
TCAATGGATGCTTAAGATGACTGCTTATGCTGATCGTTTGCTTGAAGATTTAGATGATTTAGATTGGCCAGAACCAGTTA
AGGAAATGCAAAGAAACTGGATTGGACGTTCACTTGGTGCACAAGTAACTTTTAAGATTAAGGATAGCGATAAGACTTTT
GACATCTTTACTACCCGTCCAGATACTTTGTTTGGCTGTTCATACACTGTTCTTGCTCCAGAAAACAAATTAGTGCAAGA
AATTACTACTGATGCACAGCGTGATGAAGTTAATGCTTACATTAAAAAGATTGAATCAAAATCAGATCTTGAAAGAACCG
ATTTAAACAAAGATAAGACTGGTGTATTTACTGGTGCTTACGCAATTAATCCAGTAAACGGCAAGGAAGTTCCAATTTGG
ATTTCAGATTATGTTTTGGCAAGTTACGGTACAGGTGCAGTGATGGCCGTTCCTGCTCATGATGAACGTGACTATGCTTT
TGCTACTAAATTTGGTTTGCCAATTAATCCAGTACTTGAAGGTGGAGATATTACTAAGGAAGCTTTCACTGAAGATGGTC
CACACATTAATTCTGAATTCTTAAATGGCTTGAACATTAAGGATGCCAAGAAGAAGATGGTTGAATGGCTTGAAGAGCAT
AACTGCGGTGAAAAGAAGGTTAACTATAAGCTTCGTGACTGGGACTTCAGTCGTCAACGTTACTGGGGCGAACCAATTCC
AGTTATCCACTGGGAAGATGGGGAAACTACTCTTGTTCCTGAAGATCAATTACCACTTCGCTTACCACATGCAACTGATA
TTAAGCCATCAGGTACTCCAGAAAGTCCATTAGCTAACTTGACCGATTGGGTTAATGTGGTTGATGAAAATGGTAGAAAA
GGTAAGCGTGAAACCAATACTATGCCTAACTGGGCAGGCTCAAGTTGGTACTACCTTCGTTATGTTGACCCACATAATGA
TAAAGAATTAGCTGATTACGATCTTCTTAAGAAATGGCTTCCAGTTGATCTTTACATTGGTGGTGCAGAACACGCTGTTC
GTCACCTTCTTTATGCAAGATTCTGGCACAAGGTTCTTTACGATTTAGGTGTTGTTCCAACTAAGGAACCATTCCAACGT
TTATACAATCAAGGTTTAATTTTGAAGAACCATGAGAAGATGTCTAAATCAAAGGGGAATGTTGTTAACCCTGATGATGT
TATTGACGAATATGGTGCAGACTCACTTAGAATGTATGAAATGTTCATGGGTCCACTTGATGCCTCAATTGACTGGGATG
ATAATGGCCCAGCCTCAACTAAGAAGTTCTTAGATCGTGTATGGCGTTTATTCGTTAATGATCTTGATCTTAAAGCAATT
CCACAAGAACGTATTGTTGATGAAAACGATGGTGAACTTGACAAGGTTTATGCAGAAACTGTTAAGAAGGTAACTGAAGA
CTTTGATGCTCTTCACTTCAACACTGCTATCTCTCAAATGATGGTTTTCATGAATGCAGCTCAAAAGGCTAAAACAATTC
CACGCGAATATGCAGAAGGCTTTGTTAAGCTTTTGGCACCGGTGGCTCCACACATGATGGAAGAAATCTGGCAAGTGTTT
GGTCATGATGAATCAATTAGCTATGCAGAATGGTCAACTTATGATCCAGCTAAGTTAGTTGAATCAACTGTTGAAATTAT
GGTTCAAGTAAATGGGAAACTTCGTGGTAAGTTCCAAGCTGCTAAGGATGCTGATAGAGACGAAGTTCAAAAACAAGCTA
TGGAACTTCCACACGTACAAAAATTCTTAGAAGGTAAGGACGTCAAGAAAGTTATCGTTGTACCAAATAAGATTGTTAAT
ATCGTAGCTAAATAA

Protein sequence :
MYNHKVVEKKWQDYWAKHDTFKTGTDSNKKNYYALDMFPFPSGKGLHVGHPEGYTATDIVSRMKRAQGYNVLHPMGWDAF
GLPTEQYALKTGEDPEVVTKNNIANFKRQLNKLGFSYDWDREVTTSDPNYYKWTQWVFEQMYKKGLAYEAEVPVNWSPDL
GTVVANEEIVDGKTERGGYPVYRRNMRQWMLKMTAYADRLLEDLDDLDWPEPVKEMQRNWIGRSLGAQVTFKIKDSDKTF
DIFTTRPDTLFGCSYTVLAPENKLVQEITTDAQRDEVNAYIKKIESKSDLERTDLNKDKTGVFTGAYAINPVNGKEVPIW
ISDYVLASYGTGAVMAVPAHDERDYAFATKFGLPINPVLEGGDITKEAFTEDGPHINSEFLNGLNIKDAKKKMVEWLEEH
NCGEKKVNYKLRDWDFSRQRYWGEPIPVIHWEDGETTLVPEDQLPLRLPHATDIKPSGTPESPLANLTDWVNVVDENGRK
GKRETNTMPNWAGSSWYYLRYVDPHNDKELADYDLLKKWLPVDLYIGGAEHAVRHLLYARFWHKVLYDLGVVPTKEPFQR
LYNQGLILKNHEKMSKSKGNVVNPDDVIDEYGADSLRMYEMFMGPLDASIDWDDNGPASTKKFLDRVWRLFVNDLDLKAI
PQERIVDENDGELDKVYAETVKKVTEDFDALHFNTAISQMMVFMNAAQKAKTIPREYAEGFVKLLAPVAPHMMEEIWQVF
GHDESISYAEWSTYDPAKLVESTVEIMVQVNGKLRGKFQAAKDADRDEVQKQAMELPHVQKFLEGKDVKKVIVVPNKIVN
IVAK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 0.0 64