Gene Information

Name : GOX2225 (GOX2225)
Accession : YP_192616.1
Strain : Gluconobacter oxydans 621H
Genome accession: NC_006677
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 2443597 - 2445390 bp
Length : 1794 bp
Strand : +
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGAACGCTTCCATTCCGGCCATTACGACAGGCCCTCTGCCGGCTTCCAGCAAGGTCCATGTCCAGGGCACGCTCCATGA
TATCAAAGTGCCCATGCGGCAGATTGAGATTTCGGACGAATGCCCGCTGAACGTCTATGACAGTTCCGGGCCCTATACCG
ACACCGCCATCAGCATCGACATTGCGAAAGGTCTTGCGGACAGTCGCGGCATCTGGCTTCGCAGTCGTGGCGATGTGGAG
GAGTATGACGGTCGCACGATTACGGCGGTCGATAACGGTTTTGCGGAGGGAGAACGGCTGACGCCTGCATTCCCGAACCA
GCGCCGCCCCCTGCGGGCGGTAGGGGATCGTGCGGTGACCCAGATGGCGTATGCCCGCGCTGGAATCATCACACCTGAAA
TGGAATTCGTCGCTATCCGGGAAAATATCGGCCGGACGCAGGCCCTGAAGGAAGAGCGGGATGGCGAGGATTTCGGAGCC
AGCATTCCGGACTTCGTAACGCCGGAATTCGTGCGGCAGGAAATTGCTTCAGGACGAGCGATCATTCCCGCCAATATCAA
TCACCGTGAGCTTGAGCCGATGATCATCGGACGCAATTTTCTGGTAAAGATCAATGCCAATATCGGCAATTCGGCTGTCA
CGTCTTCCATGGAAGAGGAAGTCGAAAAAATGGTGTGGTCCATCCGCTGGGGCGCGGATACCGTCATGGATCTCTCAACA
GGTCGCAATATTCATAACATCCGGGACTGGATCATCCGCAATGCTCCTGTGCCGATTGGGACGGTTCCACTGTATCAGGC
GCTGGAAAAGGTCGGCGGTATTGCGGAAGACCTGACATGGGAGATTTTCCGCGACACGCTGATCGAGCAGGCGGAGCAGG
GCGTGGATTACTTCACCATCCATGCCGGTGTCCGGCTGCACATGATCCCGCTGACGGCCCGACGGGTGACGGGCATCGTG
TCGCGCGGTGGGTCCATCATGGCGAAATGGTGCCTGCATCATCACCGCGAGAGCTTCCTGTATGAGCATTTCGAGGAGAT
CTGCGATATCTGCCGCCGCTATGACGTGTCGTTCTCGCTCGGGGACGGTCTGCGTCCGGGCTCAATTGCCGACGCTAACG
ATGCGGCGCAGTTTGCGGAGCTGGAAACGCTCGGTGAACTGACGAAAATTGCCTGGGCCAAGGACTGTCAGGTCATGATC
GAAGGTCCGGGTCATGTGCCGATGCACAAGATCAAGACCAACATGGACAAGCAGCTTGAGCACTGCCATGAAGCGCCGTT
TTATACGCTTGGCCCGCTGACGACCGATATCGCGCCCGGTTACGATCACATCACTTCGGCCATTGGTGCTGCCATGATCG
GCTGGTTCGGCACGGCCATGCTCTGCTACGTCACACCAAAGGAACATCTGGGCCTGCCGGACCGGAATGACGTCAAGACG
GGTGTCATCACCTACAAGCTTGCAGCCCATGCGGCGGATCTCGCGAAAGGCCATCCGGGCGCGCAGATGCGGGATGACGC
CCTGTCGCGGGCGCGGTTCGAGTTCCGGTGGGAAGATCAGTTCAATCTGGGGCTCGATCCCGATACCGCTCGTGCCATGC
ATGATGAAACGTTGCCCAAGCAGGCGCACAAGGTGTCCCATTTCTGCTCGATGTGTGGGCCGAAATTCTGCTCGATGAAG
ATTTCGCATGACATCCGTGCCGCGGCGGAAAAGCAGGACGGCATGGAGCAGATGGCGGAGAAATTCCGTGAAGGCGGGCA
GCTCTATGTGCCTGTGACGGAACCGGCGGAATGA

Protein sequence :
MNASIPAITTGPLPASSKVHVQGTLHDIKVPMRQIEISDECPLNVYDSSGPYTDTAISIDIAKGLADSRGIWLRSRGDVE
EYDGRTITAVDNGFAEGERLTPAFPNQRRPLRAVGDRAVTQMAYARAGIITPEMEFVAIRENIGRTQALKEERDGEDFGA
SIPDFVTPEFVRQEIASGRAIIPANINHRELEPMIIGRNFLVKINANIGNSAVTSSMEEEVEKMVWSIRWGADTVMDLST
GRNIHNIRDWIIRNAPVPIGTVPLYQALEKVGGIAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVRLHMIPLTARRVTGIV
SRGGSIMAKWCLHHHRESFLYEHFEEICDICRRYDVSFSLGDGLRPGSIADANDAAQFAELETLGELTKIAWAKDCQVMI
EGPGHVPMHKIKTNMDKQLEHCHEAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWFGTAMLCYVTPKEHLGLPDRNDVKT
GVITYKLAAHAADLAKGHPGAQMRDDALSRARFEFRWEDQFNLGLDPDTARAMHDETLPKQAHKVSHFCSMCGPKFCSMK
ISHDIRAAAEKQDGMEQMAEKFREGGQLYVPVTEPAE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 0.0 67
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 0.0 67
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 0.0 66