Gene Information

Name : fliI (GOX1694)
Accession : YP_192090.1
Strain : Gluconobacter oxydans 621H
Genome accession: NC_006677
Putative virulence/resistance : Virulence
Product : flagellum-specific ATP synthase
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : 3.6.3.14
Position : 1852667 - 1854025 bp
Length : 1359 bp
Strand : +
Note : involved in type III protein export during flagellum assembly

DNA sequence :
ATGGACGACTACGACAGACTGCTCGAAAGGCTTTCGAACCTCACCTGCGACTGGGTTGTAGGAAGCGTTAAAGACGTTAT
CGGTCTCTGTCTGACCGTTATCGGACTCGAAGGTTTCATTACGATTGGAGACCGAGTCGCGGTGAAAGCGCTTGACGGAC
GGGTTGTGCAATCCGAGGTTGTGGGCTTTCAGGGTGATGTCGCGCGGCTCATGTCCTTCGGGCCTCTGGACGGAATTGGT
CCGGGCTGCGAGGCTAGGATTCCGCTGAACCGTCATGATGGTGGCCTTGGCGTTAATGAAAGCTGGCTGGGGCGCGTGCT
GGATCCGCTGGGACAGCCGATCGACGGGAAGGGGCCTCTGTTTCCGTCGTTTGAGCGGCAGCCGGTCCAGTGTCCTCCGC
CCAATGCTGCAAGCCGGGCGCGGCTTGGCGAGCGTATCGACCTCGGGGTCCGCGCCCTTGATACCTTCACGACCTGCCGG
CGCGGACAGAGGCTCGGGCTTTTCGCAGGGTCGGGTGTCGGGAAATCCACATTGCTGTCCATGCTCGCCCGCGGCGCGGA
CTGTGATGTCGCCGTGATCTCGCTTGTGGGTGAGCGTGGGCGCGAGGTGCGGGAGTTCATCGAGGATGATCTCGGGCCGG
AAGGGCTGGCGCGGAGTGTGCTGGTGATTGCGACTTCTGATTCACCGCCACTGATGCGTCGCGAAGCCGCCCTGTCCGCC
ATGGCCATCGCGGAATATTTCCGGAACCAGGGCAAATCGGTCCTGCTGCTGATGGACAGCGTGACGCGGTTCTGCATGGC
GCTGCGTGAAATCGGTCTGTCAGCCGGAGAGCCGCCTGCGACGCGGGGTTATCCGCCTTCGGTTTTTGCCGAACTGCCGC
GTCTTCTGGAGCGGGCGGGGCCTGGCTATGCCGATCAGGGCATGATCACGGCGCTCTTCACGGTTCTTGTGGAGGGGGAT
GACCAGAATGAGCCGGTTGCGGATGCCGTGCGTGGCATTCTGGACGGGCATATCATTCTTGACCGCAAGATCGGCGAGCA
GGGGCGGTATCCTGCCATTGATGTTCTGCGTTCCCTGTCGCGTGCGGTGCCGGGATGTAATTCGCCTGAGGAAAATGCTC
TGACGCAACGCGCGCGGGCAGCGATGGCGACCTATCAGCGGATGGCAGATATGATCCGGCTGGGAGCCTACAAACCCGGA
ACGGATCGTGAGGTGGATGAAGCCATCGCCCTCATGCCGAAGCTAAACGAGTTCCTGTCTCAGGGGCGGAACGAACGCAC
CACGCGCGCCGAGGCCTTTGAACAGCTGGCGCAGATCATGCAGATGCCGCTGAAAAACCTCCCCCCGAATGAATCGTAA

Protein sequence :
MDDYDRLLERLSNLTCDWVVGSVKDVIGLCLTVIGLEGFITIGDRVAVKALDGRVVQSEVVGFQGDVARLMSFGPLDGIG
PGCEARIPLNRHDGGLGVNESWLGRVLDPLGQPIDGKGPLFPSFERQPVQCPPPNAASRARLGERIDLGVRALDTFTTCR
RGQRLGLFAGSGVGKSTLLSMLARGADCDVAVISLVGERGREVREFIEDDLGPEGLARSVLVIATSDSPPLMRREAALSA
MAIAEYFRNQGKSVLLLMDSVTRFCMALREIGLSAGEPPATRGYPPSVFAELPRLLERAGPGYADQGMITALFTVLVEGD
DQNEPVADAVRGILDGHIILDRKIGEQGRYPAIDVLRSLSRAVPGCNSPEENALTQRARAAMATYQRMADMIRLGAYKPG
TDREVDEAIALMPKLNEFLSQGRNERTTRAEAFEQLAQIMQMPLKNLPPNES

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lscN AAO18044.1 LscN Virulence TTSS locus Protein 6e-83 53
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 2e-82 48
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 2e-82 48
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-81 48
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 4e-82 48
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 4e-82 48
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-82 48
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 1e-81 48
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 6e-81 47
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 5e-81 47
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 6e-76 47
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 9e-72 47
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 9e-72 47
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 7e-73 47
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 2e-72 47
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 9e-73 47
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 2e-58 46
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 3e-62 45
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 6e-60 45
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 6e-60 45
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 6e-64 44
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 6e-64 44
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 2e-66 44
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 6e-70 44
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 5e-70 44
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 1e-69 44
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 9e-72 44
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 4e-62 43
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 9e-66 43
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 9e-66 43
escN YP_003236088.1 translocator EscN Virulence LEE Protein 8e-70 43
escN NP_290268.1 hypothetical protein Virulence LEE Protein 6e-70 43
escN AAC31513.1 L0034 Virulence LEE Protein 4e-70 43
ECs4568 NP_312595.1 EscN Virulence LEE Protein 6e-70 43
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 4e-70 43
unnamed AAL06369.1 EscN Virulence LEE Protein 2e-69 43
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 3e-69 43
escN AAC38383.1 EscN Virulence LEE Protein 7e-70 43
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 1e-61 42
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 1e-61 42
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 1e-61 42
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 1e-61 42
escN YP_003223475.1 translocator EscN Virulence LEE Protein 3e-69 42
escN AAK26715.1 EscN Virulence LEE Protein 8e-69 42
escN AAL57542.1 EscN Virulence LEE Protein 8e-69 42
escN CAC81862.1 EscN protein Virulence LEE II Protein 3e-69 42
escN CAI43874.1 EscN protein Virulence LEE Protein 2e-69 42
invC AAS66861.1 InvC Not tested SSR-2 Protein 1e-61 41
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 2e-59 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fliI YP_192090.1 flagellum-specific ATP synthase VFG0390 Protein 6e-83 52
fliI YP_192090.1 flagellum-specific ATP synthase VFG0192 Protein 2e-80 52
fliI YP_192090.1 flagellum-specific ATP synthase VFG2144 Protein 6e-88 48
fliI YP_192090.1 flagellum-specific ATP synthase VFG0048 Protein 3e-84 48
fliI YP_192090.1 flagellum-specific ATP synthase VFG1254 Protein 9e-83 48
fliI YP_192090.1 flagellum-specific ATP synthase VFG2499 Protein 1e-79 48
fliI YP_192090.1 flagellum-specific ATP synthase VFG0515 Protein 4e-73 47
fliI YP_192090.1 flagellum-specific ATP synthase VFG2331 Protein 2e-78 46
fliI YP_192090.1 flagellum-specific ATP synthase VFG0812 Protein 3e-70 43
fliI YP_192090.1 flagellum-specific ATP synthase VFG0730 Protein 4e-70 43
fliI YP_192090.1 flagellum-specific ATP synthase VFG0555 Protein 4e-62 42